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Neanderthals boosted our immune system
Max-Planck-Gesellschaft ^ | January 07, 2016 | SJ/HR

Posted on 01/07/2016 10:51:53 PM PST by SunkenCiv

When modern humans met Neanderthals in Europe and the two species began interbreeding many thousands of years ago, the exchange left humans with gene variations that have increased the ability of those who carry them to ward off infection. This inheritance from Neanderthals may have also left some people more prone to allergies. Researchers of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, and the Institut Pasteur and the CNRS in Paris, France, report about the discoveries in two independent studies, adding to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection. "We found that interbreeding with archaic humans, the Neanderthals and Denisovans, has influenced the genetic diversity in present-day genomes at three innate immunity genes belonging to the human Toll-like-receptor family," says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. "These, and other, innate immunity genes present higher levels of Neanderthal ancestry than the remainder of the coding genome," adds Lluis Quintana-Murci of the Institut Pasteur and the CNRS in Paris. "This highlights how important introgression events, the movement of genes across species, may have been in the evolution of the innate immunity system in humans."

Earlier studies have shown that one to six percent of modern Eurasian genomes were inherited from ancient hominins, such as Neanderthal or Denisovans. Both new studies highlight the functional importance of this inheritance on Toll-like receptor (TLR) genes TLR1, TLR6, and TLR10. These TLR genes are expressed on the cell surface, where they detect and respond to components of bacteria, fungi, and parasites. These immune receptors are essential for eliciting inflammatory and anti-microbial responses and for activating an adaptive immune response.

(Excerpt) Read more at mpg.de ...


TOPICS: History; Science; Travel
KEYWORDS: denisovans; godsgravesglyphs; helixmakemineadouble; neandertal; neandertals; neanderthal; neanderthals
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To: RedHeeler
Only in the suburbs Hugh ...

JACKSON BROWNE - STAY - LIVE (1978)

Rosemary Butler

21 posted on 01/08/2016 1:20:22 AM PST by Liberty Valance (Keep a Simple Manner for a Happy Life :o)
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To: Liberty Valance

Jackson Browne? May have played poker with him once, in LA. Lower Alabama- around ‘72. Venice beach. Don’t know the broad.


22 posted on 01/08/2016 1:28:43 AM PST by RedHeeler
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To: RedHeeler

https://www.youtube.com/watch?v=2oEsWi88Qv0
The Third Man - Anton Karas

;o)


23 posted on 01/08/2016 1:33:52 AM PST by Liberty Valance (Keep a Simple Manner for a Happy Life :o)
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To: Liberty Valance

Thanks.


24 posted on 01/08/2016 1:48:40 AM PST by RedHeeler
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To: StayAt HomeMother; Ernest_at_the_Beach; decimon; 1010RD; 21twelve; 24Karet; 2ndDivisionVet; ...
KEYWORDS: neandertal; neandertals; neanderthal; neanderthals
The Neandertal Enigma
by James Shreeve

in local libraries
"Frayer's own reading of the record reveals a number of overlooked traits that clearly and specifically link the Neandertals to the Cro-Magnons. One such trait is the shape of the opening of the nerve canal in the lower jaw, a spot where dentists often give a pain-blocking injection. In many Neandertal, the upper portion of the opening is covered by a broad bony ridge, a curious feature also carried by a significant number of Cro-Magnons. But none of the alleged 'ancestors of us all' fossils from Africa have it, and it is extremely rare in modern people outside Europe." [pp 126-127]

25 posted on 01/08/2016 4:26:50 AM PST by SunkenCiv (Here's to the day the forensics people scrape what's left of Putin off the ceiling of his limo.)
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To: imardmd1

There are no Neandertal mitrochondreal examples found in genetic testing, nor Y chromosomes.

The best explanation for this is human women giving birth to the hybrid children, but never the other way around, and that none of the male hybrids lived.

A short story on that concept plus mocking post-human genetic engineering

A Step Back in Time, a short story
http://hubpages.com/literature/When-Time-Should-Have-Stood-Still


26 posted on 01/08/2016 10:44:38 AM PST by tbw2
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The Iceman’s Stomach Bugs Offer Clues to Ancient Human Migration
smithsonianmag | 01/07/2016 | Brian Handwerk
Posted on 01/07/2016 7:00:24 PM PST by BenLurkin
http://www.freerepublic.com/focus/chat/3381071/posts


27 posted on 01/08/2016 12:41:13 PM PST by SunkenCiv (Here's to the day the forensics people scrape what's left of Putin off the ceiling of his limo.)
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To: tbw2

Thanks for your insight! I’ll try to check your thesis, because it is very interesting as possibly applying to Genesis 6:1-2, a thorny issue to a lot of speculation.


28 posted on 01/08/2016 10:48:02 PM PST by imardmd1 (Fiat Lux)
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