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Keyword: ldn

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  • The 10 Deadliest Cancers—and How to Stop Them (includes free downloadable PDF guide)

    07/27/2025 5:57:49 PM PDT · by ransomnote · 77 replies
    Substack.com ^ | Jul 19, 2025 | Dr. Paul Marik, Independent Medical Alliance and Justus R. Hope
    [H/T CheshireTheCat]The 10 deadliest cancers share one thing: a common metabolic driver. Learn how repurposed drugs can help stop them, and download the free guide by Dr. Paul Marik and Dr. Justus R. Hope.Each year, cancer takes more than 600,000 lives in the United States and 10 million globally. It’s the second-leading cause of death in America, and the rates are not going down. Despite massive fundraising campaigns and billion-dollar research budgets, meaningful innovation in cancer treatment has stalled.In fact, most patients today are still offered the same three options they would have been decades ago: surgery, chemotherapy, and radiation.But...
  • Low-dose naltrexone (LDN): Tricking the body to heal itself

    09/04/2011 8:21:54 PM PDT · by decimon · 23 replies
    Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) to treat cancer and autoimmune diseases, exerts a profound inhibitory effect on cell proliferation. It has been postulated that opioid receptor blockade by LDN provokes a compensatory elevation in endogenous opioids and opioid receptors that can function after LDN is no longer available. Using a novel tissue culture model of LDN action, the mechanism of LDN has been found to target the opioid growth factor (OGF, [Met5]-enkephalin) and OGF...