Research from has uncovered a critical mechanism by which mutations in the p53 protein—a key tumor suppressor known as the "guardian of the genome"—turn other proteins into cancer-promoting agents. The study, led by Dr. Jerson Lima Silva, offers fresh insights into a process that plays a pivotal role in the development and progression of many cancers. p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged cells before they can become malignant. However, in more than 50% of all tumors, mutations in p53 undermine its protective role, converting it...