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Posts by WmShirerAdmirer

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  • Supreme Courts Rejects Bid to Restrict Access To Abortion Pill

    06/13/2024 11:29:44 AM PDT · 20 of 55
    WmShirerAdmirer to Coronal

    TTT # 2022-2468
    NDA 020687
    ANDA 091178

    Mifepristone U.S. Post-Marketing Adverse Events Summary through 12/31/2022

    The following information is from United States (U.S.) post-marketing reports received by FDA of adverse events that occurred among patients who had taken mifepristone for medical termination of pregnancy

    https://www.fda.gov/media/164331/download

    (SEE LINK ABOVE FOR DATES RANGES OF ADVERSE EVENTS FOR TABLE 1 AND 2 LISTED BELOW)

    Table 1. Cumulative Post-Marketing Fatal and Ectopic Pregnancy Reports in U.S. Women Who Used Mifepristone for Medical Termination of Pregnancy

    Date range of cumulative reports 09/28/00† - 12/31/22

    Died ‡ 32

    *Ectopic pregnancies || 97
    † U.S. approval date

    Table 2. Post-Marketing Adverse Events in U.S. Women Who Used Mifepristone for Medical Termination of Pregnancy

    Date ranges of reports
    received

    09/28/00† - 10/31/12 and

    11/01/12 - 12/31/22‡

    Cases with any adverse event 2740 1478

    Hospitalized, excluding deaths 768 281

    *Experienced blood loss requiring

    transfusions § 416 188

    Infections || 308 110
    *Severe infections 57 18

  • Supreme Courts Rejects Bid to Restrict Access To Abortion Pill

    06/13/2024 10:57:56 AM PDT · 18 of 55
    WmShirerAdmirer to Coronal

    You’re right! Look at this and other reports listed here.

    Deaths and Severe Adverse Events after the use of Mifepristone as an Abortifacient from September 2000 to February 2019

    https://pubmed.ncbi.nlm.nih.gov/33939340/

    Kathi Aultman 1, Christina A Cirucci, Donna J Harrison 2, Benjamin D Beran 3, Michael D Lockwood 4, Sigmund Seiler 5
    Affiliations expand
    PMID: 33939340
    Abstract
    Objectives: Primary: Analyze the Adverse Events (AEs) reported to the Food and Drug Administration (FDA) after use of mifepristone as an abortifacient. Secondary: Analyze maternal intent after ongoing pregnancy and investigate hemorrhage after mifepristone alone.

    Methods: Adverse Event Reports (AERs) for mifepristone used as an abortifacient, submitted to the FDA from September 2000 to February 2019, were analyzed using the National Cancer Institute’s Common Terminology Criteria for Adverse Events (CTCAEv3).

    Results: The FDA provided 6158 pages of AERs. Duplicates, non-US, or AERs previously published (Gary, 2006) were excluded. Of the remaining, there were 3197 unique, US-only AERs of which there were 537 (16.80%) with insufficient information to determine clinical severity, leaving 2660 (83.20%) Codable US AERs. (Figure 1). Of these, 20 were Deaths, 529 were Life-threatening, 1957 were Severe, 151 were Moderate, and 3 were Mild.

    The deaths included: 9 (45.00%) sepsis, 4 (20.00%) drug toxicity/overdose, 1 (5.00%) ruptured ectopic pregnancy, 1 (5.00%) hemorrhage, 3 (15.00%) possible homicides, 1 (5.00%) suicide, 1 (5.00%) unknown. (Table 1).

    Retained products of conception and hemorrhage caused most morbidity. There were 75 ectopic pregnancies, including 26 ruptured ectopics (includes one death).

    There were 2243 surgeries including 2146 (95.68%) D&Cs of which only 853 (39.75%) were performed by abortion providers.

    Of 452 patients with ongoing pregnancies, 102 (22.57%) chose to keep their baby, 148 (32.74%) had terminations, 1 (0.22%) miscarried, and 201 (44.47%) had unknown outcomes.

    Hemorrhage occurred more often in those who took mifepristone and misoprostol (51.44%) than in those who took mifepristone alone (22.41%).

    Conclusions: Significant morbidity and mortality have occurred following the use of mifepristone as an abortifacient. A pre-abortion ultrasound should be required to rule out ectopic pregnancy and confirm gestational age. The FDA AER system is inadequate and significantly underestimates the adverse events from mifepristone.

    A mandatory registry of ongoing pregnancies is essential considering the number of ongoing pregnancies especially considering the known teratogenicity of misoprostol.

    The decision to prevent the FDA from enforcing REMS during the COVID-19 pandemic needs to be reversed and REMS must be strengthened.

    Keywords: Abortifacient; Abortion Pill; Adverse Event Reports; Adverse Events; DIY Abortion; Drug Safety; Emergency Medicine; FAERS; FDA; Medical Abortion; Medical Abortion Complications; Mifeprex; Mifepristone; Misoprostol; No touch abortion; Post-marketing Surveillance; REMS; RU-486; Risk Evaluation Mitigation Strategy; Self-Administered Abortion.

    Copyright © 2021 by the National Legal Center for the Medically Dependent and Disabled, Inc.

    PubMed Disclaimer

    Similar articles
    Mifepristone Adverse Events Identified by Planned Parenthood in 2009 and 2010 Compared to Those in the FDA Adverse Event Reporting System and Those Obtained Through the Freedom of Information Act.
    Cirucci CA, Aultman KA, Harrison DJ.
    Health Serv Res Manag Epidemiol. 2021 Dec 21;8:23333928211068919. doi: 10.1177/23333928211068919. eCollection 2021 Jan-Dec.
    PMID: 34993274 Free PMC article.

    Mifepristone With Buccal Misoprostol for Medical Abortion: A Systematic Review.
    Chen MJ, Creinin MD.
    Obstet Gynecol. 2015 Jul;126(1):12-21. doi: 10.1097/AOG.0000000000000897.
    PMID: 26241251 Review.

    First-trimester medical abortion with mifepristone 200 mg and misoprostol: a systematic review.
    Raymond EG, Shannon C, Weaver MA, Winikoff B.
    Contraception. 2013 Jan;87(1):26-37. doi: 10.1016/j.contraception.2012.06.011. Epub 2012 Aug 13.
    PMID: 22898359 Review.

    Analysis of severe adverse events related to the use of mifepristone as an abortifacient.
    Gary MM, Harrison DJ.
    Ann Pharmacother. 2006 Feb;40(2):191-7. doi: 10.1345/aph.1G481. Epub 2005 Dec 27.
    PMID: 16380436

    Low-dose mifepristone 200 mg and vaginal misoprostol for abortion.
    Schaff EA, Eisinger SH, Stadalius LS, Franks P, Gore BZ, Poppema S.
    Contraception. 1999 Jan;59(1):1-6. doi: 10.1016/s0010-7824(98)00150-4.
    PMID: 10342079 Clinical Trial.
    See all similar articles
    Cited by
    Mifepristone Antagonization with Progesterone to Avert Medication Abortion: A Scoping Review.
    DeBeasi PLC.
    Linacre Q. 2023 Nov;90(4):395-407. doi: 10.1177/00243639231176592. Epub 2023 May 29.
    PMID: 37969420 Free PMC article.
    Self-Managed Medication Abortion: Implications for Clinical Practice.
    Cirucci CA.
    Linacre Q. 2023 Aug;90(3):273-289. doi: 10.1177/00243639221128389. Epub 2022 Dec 12.
    PMID: 37841380

    Comparison of outpatient with inpatient mifepristone usage for cervical ripening: A randomised controlled trial.
    Baev O, Karapetian A, Babich D, Sukhikh G.
    Eur J Obstet Gynecol Reprod Biol X. 2023 May 16;18:100198. doi: 10.1016/j.eurox.2023.100198. eCollection 2023 Jun.
    PMID: 37234794 Free PMC article.

    Mifepristone Adverse Events Identified by Planned Parenthood in 2009 and 2010 Compared to Those in the FDA Adverse Event Reporting System and Those Obtained Through the Freedom of Information Act.
    Cirucci CA, Aultman KA, Harrison DJ.
    Health Serv Res Manag Epidemiol. 2021 Dec 21;8:23333928211068919. doi: 10.1177/23333928211068919. eCollection 2021 Jan-Dec.
    PMID: 34993274 Free PMC article.

    A Longitudinal Cohort Study of Emergency Room Utilization Following Mifepristone Chemical and Surgical Abortions, 1999-2015.
    Studnicki J, Harrison DJ, Longbons T, Skop I, Reardon DC, Fisher JW, Tsulukidze M, Craver C.
    Health Serv Res Manag Epidemiol. 2021 Nov 9;8:23333928211053965. doi: 10.1177/23333928211053965. eCollection 2021 Jan-Dec.
    Retraction in: Health Serv Res Manag Epidemiol. 2024 Feb 5;11:23333928231216699. doi: 10.1177/23333928231216699.
    PMID: 34778493 Free PMC article.

    MeSH terms
    Abortifacient Agents* / adverse effects
    Abortifacient Agents, Steroidal / adverse effects
    Abortion, Induced / adverse effects
    COVID-19
    Female
    Humans
    Mifepristone / adverse effects*
    Misoprostol
    Pandemics
    Pregnancy
    SARS-CoV-2
    Substances
    Abortifacient Agents
    Abortifacient Agents, Steroidal
    Misoprostol
    Mifepristone
    Related information
    MedGen
    PubChem Compound (MeSH Keyword)

  • X: DiedSuddenly @ DiedSuddenly Live now

    06/07/2024 5:26:37 PM PDT · 12 of 16
    WmShirerAdmirer to Dogbert41

    Thanks for posting this video!

  • X: DiedSuddenly @ DiedSuddenly Live now

    06/07/2024 4:03:14 PM PDT · 2 of 16
    WmShirerAdmirer to WmShirerAdmirer

    Also: James O’Keefe @JamesOKeefeIII

    We’re all going to be tested over the next few years with a terrible choice.

    Preserve your livelihood and lose your soul.

    Or preserve your soul and lose your livelihood.

    Will you live a lie in order to survive?

    Or will you live the truth and face ruin
    https://x.com/JamesOKeefeIII/status/1798975900593389609

  • X: DiedSuddenly @ DiedSuddenly Live now

    06/07/2024 3:58:32 PM PDT · 1 of 16
    WmShirerAdmirer
    Comment: Josette caruso @josettecaruso

    Mexican Health Secretary Jorge Alcocer on Thursday denied an announcement by the World Health Organization (WHO) that a man’s death in Mexico was caused by a strain of bird flu that had never before been found in a human.

    During a morning briefing, Alcocer rebuffed the WHO’s announcement and assured that the 59-year-old man, who was reported to have died from the A(H5N2) strain of avian influenza, “died from other causes, mainly kidney and respiratory failure.”

    Alcocer urged people to remain calm and to take the WHO’s announcement with caution because it is "not accurate."

    "I can point out that the statement made by the World Health Organization is pretty bad, since it speaks of a fatal case (of bird flu), which was not the case," he said.

    On Wednesday, the WHO announced that a resident of Mexico became the world’s first person to die from a bird flu strain not previously detected in humans

  • AUDIO: Justice Neil Gorsuch Blows Up Department of Injustice’s Case Against J6 Protesters

  • Secretaries Of State Won’t Explain ‘Coordinated’ Effort To Fight ‘Common Adversary’ In 2024

    03/22/2024 2:09:19 PM PDT · 28 of 44
    WmShirerAdmirer to Triple

    Ditto!!!

  • Secretaries Of State Won’t Explain ‘Coordinated’ Effort To Fight ‘Common Adversary’ In 2024

    03/22/2024 2:06:25 PM PDT · 27 of 44
    WmShirerAdmirer to Twotone

    RICO any one?

  • Please lift my beloved husband up in prayer, he is very ill.

    02/25/2024 2:13:56 PM PST · 17 of 116
    WmShirerAdmirer to Patriot777

    Prayers

  • The "Salt & Pepper Michigan Republican Party," 2 Dueling State Conventions on March 2, 2024

    02/23/2024 4:15:28 AM PST · 8 of 9
    WmShirerAdmirer to WmShirerAdmirer

    All: Thank you all, I will be taking these ideas here back to the Macomb County Republican Party Headquarters (the grass root Michigan county that gave Trump the win in 2016 and close to a win with 263,863 votes in 2020) for insight and debate.

    2016 Macomb

    224,665. Trump*

    176,317. Clinton

    2020 Macomb

    263,863 Trump*

    223,952 Biden

    * Winner

  • The "Salt & Pepper Michigan Republican Party," 2 Dueling State Conventions on March 2, 2024

    02/22/2024 7:07:57 PM PST · 1 of 9
    WmShirerAdmirer
    Civil War within the "Salt and Pepper Michigan Republican Party", what a sickening mess the principals have cooked up and are serving Trump!
  • Kamala Harris Thinks It’s “Cruel” to Protect Babies From Abortions

    01/09/2024 5:44:15 PM PST · 10 of 14
    WmShirerAdmirer to All

    Why don’t we Americans face it and call it as it is, the Vice President isn’t human,she is brainless and as thoughtless and senseless as our President. They are another specie Democratoids in physical skin and bones. Unbelievable that they are in their positions of the government which was the greatest and most compassionate nation on earth throughout its history.

  • World’s first tampons for men are an ‘insult’ to women

    12/03/2023 5:38:54 PM PST · 54 of 65
    WmShirerAdmirer to Harmless Teddy Bear

    Love your reply, it is priceless!

  • ‘Hate Speech Police Are Coming For You’ – Lawyer Speaks Out About Impending House Legislation

    06/10/2023 12:17:17 PM PDT · 21 of 51
    WmShirerAdmirer to digger48

    you’re right, just as GrandJediMasterYoda wrote “a hate crime if that person intimidates or harasses another individual”
    Good God, there are so many ways that can be interpreted. “

  • ‘Hate Speech Police Are Coming For You’ – Lawyer Speaks Out About Impending House Legislation

    06/10/2023 12:10:43 PM PDT · 18 of 51
    WmShirerAdmirer to Antihero101607

    Thanks!

  • ‘Hate Speech Police Are Coming For You’ – Lawyer Speaks Out About Impending House Legislation

    06/10/2023 12:05:14 PM PDT · 14 of 51
    WmShirerAdmirer to Worldtraveler once upon a time

    “Class action law suit against the state and legislature!”
    Good idea!

  • ‘Hate Speech Police Are Coming For You’ – Lawyer Speaks Out About Impending House Legislation

    06/10/2023 11:59:37 AM PDT · 13 of 51
    WmShirerAdmirer to frank ballenger

    kudos to fellow Michigander, telling it like it is.

  • ‘Hate Speech Police Are Coming For You’ – Lawyer Speaks Out About Impending House Legislation

    06/10/2023 11:36:34 AM PDT · 1 of 51
    WmShirerAdmirer
    Unconstitutional but will probably pass, Michiganders, both Republicans and Conservative Democrats are braindead!

    https://slaynews.com/news/facebook-cracks-down-christian-content-labels-hate-speech/

    https://www.libertynation.com/democrats-look-to-kill-online-free-speech-with-new-federal-agency/

  • Dentists: Unexplained Pain, Tooth Loss and Bone Problems May Be Linked to COVID-19 Vaccine

    05/07/2023 3:19:56 PM PDT · 34 of 43
    WmShirerAdmirer to WmShirerAdmirer

    All:
    Just read the 286 Comments on the original Epoch Times article and they were frightening and extremely sad how people are suffering...

    https://www.theepochtimes.com/health/dentists-unexplained-pain-tooth-loss-and-bone-problems-may-be-linked-to-covid-19-vaccine_5201385.html?ea_src=open&ea_med=search

    Steve Hawes 1 week ago
    “I’m an Infectious Diseases MD who drove 14 hours for each of my first two doses of vaccine. At age 72 I have had only one cavity life long. Within a month of the second dose painful ulcers developed along my gum lines. Ultimately, I lost a canine tooth on the upper right mandible. After 6 months and no more vaccines these have resolved.

    I tried to report the reaction to the VAERS system. At first the notice was rejected. Only after I registered as an MD was the possible adverse reaction accepted.
    No more jabs at our house after my wife, daughter have had side affects possibly related to the vaccine.”

    drlafrom 1 day ago
    “My wife got the vaxx despite my opinions. She had rapid decay in eight of her teeth needing crowns in the last 18 months! ridiculous.”

    Beth 6 Days ago
    “My beloved and irreplaceable mother is dead from this. She got all the fake-vaccines and all the boosters, no matter what I told her.
    She began to suffer with many horrible illnesses immediately after the first shot. Before, she was an athlete, swimmer, runner, extreme healthy eater. All the conditions combined and the tooth pain was beyond what she could stand. She couldn’t eat, then couldn’t drink, then died in my arms, her face wet with my tears. Thanks Doctor Fauci. May God have mercy on your evil soul.”

    Rose2021 1 week ago
    “A hell of a lot of people seem to be having swallowing issues. I have a friend who has had 5 operations where botox was injected into her throat. It obviously hasn’t worked too well.
    I’ve had the pleasure of having lunch with her and watching her gag all the way through. Coincidentally it started right after she had the jab but she can’t see it.
    Another fellow of 55 can’t speak any more as he reckons his mouth is full of ulcers. He has to hold his head up with his hands.”

  • Dentists: Unexplained Pain, Tooth Loss and Bone Problems May Be Linked to COVID-19 Vaccine

    05/07/2023 12:38:45 PM PDT · 5 of 43
    WmShirerAdmirer to Jane Long

    Thanks. “These maladies would typically be seen in older individuals rather than in a younger, healthy population.”