Free Republic

https://www.sciencedirect.com/science/article/pii/S0166354220302011 The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro Highlights • Ivermectin is an inhibitor of the COVID-19 causative virus (SARS-CoV-2) in vitro. • A single treatment able to effect ∼5000-fold reduction in virus at 48h in cell culture. • Ivermectin is FDA-approved for parasitic infections, and therefore has a potential for repurposing. • Ivermectin is widely available, due to its inclusion on the WHO model list of essential medicines. Abstract Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report...

Amid a barrage of research on finding treatment for new coronavirus, Australian scientists have found that a common anti-parasitic drug killed SARS-CoV-2 virus, growing in cell culture, within 48 hours in lab settings. Ivermectin is an FDA-approved anti-parasitic drug that has also been shown to be effective in vitro against a broad range of viruses including HIV, dengue, influenza and Zika virus. Published in the journal Antiviral Research, the study from Monash University showed that a single dose of Ivermectin could stop the coronavirus growing in cell culture -- effectively eradicating all genetic material of the virus within two days....

Researchers in Australia report that Ivermectin, an FDA-approved drug commonly used to treat parasites, appears to be effective in treating the SARS-COV-2 coronavirus (COVID-19). The drug is widely available and can be “repurposed” for this application, doctors said. The ScienceDirect journal, Antiviral Research, published an article by a group of Australian researchers from Monash University in Melbourne reporting that Ivermectin appears to be effective at inhibiting the coronavirus that causes COVID-19. The article states: Ivermectin is an inhibitor of the COVID-19 causative virus (SARS-CoV-2) in vitro. A single treatment able to effect ∼5000-fold reduction in virus at 48h in cell...

An anti-parasitic head lice drug available around the world has been found to kill COVID-19 in the lab within 48 hours. A Monash University-led study has shown a single dose of the drug Ivermectin could stop the SARS-CoV-2 virus growing in cell culture. 'We found that even a single dose could essentially remove all viral RNA (effectively removed all genetic material of the virus) by 48 hours and that even at 24 hours there was a really significant reduction in it,' Monash Biomedicine Discovery Institute's Dr Kylie Wagstaff said on Friday. While it's not known how Ivermectin works on the...

Gripe as we might, consumers understand that price increases do happen. What’s not as easily understood is how the price for something can go from $13.50 one day to $750 the next — especially when it’s a generic drug used to save lives. For decades, Daraprim (pyrimethamine), an anti-parasitic used to treat malaria and toxoplasmosis, had been made by GlaxoSmithKline and sold for as little as $1/tablet until not that long ago. Then in 2010 GSK sold the drug to CorePharma, which began to raise the price. Within a year, revenue from Daraprim jumped nearly ten times even though the...