Posted on 01/30/2003 9:33:28 AM PST by matthew_the_brain
Letters of Recommendation
Before you ask me to write you a letter of recommendation for graduate or professional school in the biomedical sciences, there are several criteria that must be met. The request for a letter is best made by making an appointment to discuss the matter with me after considering these three criteria:
Criterion 1
You should have earned an "A" from me in at least one semester that you were taught by me.
Criterion 2
I should know you fairly well. Merely earning an "A" in a lower-division class that enrolls 500 students does not guarantee that I know you. In such a situation, all I would be able to provide is a very generic letter that would not be of much help in getting you into the school of your choice. You should allow me to become better acquainted with you. This can be done in several ways:
1) by meeting with me regularly during my office hours to discuss biological questions. 2) by enrolling in an Honors section taught by me. 3) by enrolling in my section of BIOL 4301 and serving as an undergraduate TA (enrollment is by invitation only). 4) by serving as the chairman or secretary of the Biology Advisory Committee.
Criterion 3
If you set up an appointment to discuss the writing of a letter of recommendation, I will ask you: "How do you think the human species originated?" If you cannot truthfully and forthrightly affirm a scientific answer to this question, then you should not seek my recommendation for admittance to further education in the biomedical sciences.
Why do I ask this question? Lets consider the situation of one wishing to enter medical school. Whereas medicine is historically rooted first in the practice of magic and later in religion, modern medicine is an endeavor that springs from the sciences, biology first among these. The central, unifying principle of biology is the theory of evolution, which includes both micro- and macro-evolution, and which extends to ALL species. How can someone who does not accept the most important theory in biology expect to properly practice in a field that is so heavily based on biology? It is hard to imagine how this can be so, but it is easy to imagine how physicians who ignore or neglect the Darwinian aspects of medicine or the evolutionary origin of humans can make bad clinical decisions. The current crisis in antibiotic resistance is the result of such decisions. For others, please read the citations below.
Good medicine, like good biology, is based on the collection and evaluation of physical evidence. So much physical evidence supports the evolution of humans from non-human ancestors that one can validly refer to the "fact" of human evolution, even if all of the details are not yet known. One can deny this evidence only at the risk of calling into question ones understanding of science and of the method of science. Such an individual has committed malpractice regarding the method of science, for good scientists would never throw out data that do not conform to their expectations or beliefs. This is the situation of those who deny the evolution of humans; such a one is throwing out information because it seems to contradict his/her cherished beliefs. Can a physician ignore data that s/he does not like and remain a physician for long? No. If modern medicine is based on the method of science, then how can someone who denies the theory of evolution -- the very pinnacle of modern biological science -- ask to be recommended into a scientific profession by a professional scientist?
If you still want to make an appointment, you can do so in person during office hours (M-Th, 3:30-4:00), or by phoning my office at 742-2729, or by e-mailing me at michael.dini@ttacs.ttu.edu
Citations
Ewald, P.W. 1993. Evolution of infectious disease. Oxford University Press, New York, pp. 298.
Ewald, P.W. 1993. The evolution of virulence. Scientific American 268:86-98.
Morgan, E. 1990. The scars of evolution. Oxford University Press, New York, pp. 196.
Myers, J.H. and L.E. Rothman. 1995. Virulence and transmission of infectious diseases in humans and insects: evolutionary and demographic patterns. Trends in Ecology and Evolution 10(5):194-198.
Nesse, R.M. and G.C. Williams. 1994. Why we get sick. Times Books, New York, pp. 291.
_____1997. Evolutionary biology in the medical curriculum -- what every physician should know. BioScience 47(10):664-666.
Rose, Michael. 1998. Darwin's Spectre. Princeton University Press, Princteon, NJ. pp. 233.
Seachrist, L. 1996. Only the strong survive: the evolution of a tumor favors the meanest, most aggressive cells. Science News 49:216-217.
Stearns, S.C. (ed.) 1999. Evolution in Health and Disease. Oxford University Press. pp. 328.
Trevathan, W.R., Smith, E.O. and J.J. McKenna (eds.). 1999. Evolutionary Medicine. Oxford University Press. pp. 480.
Williams, G.C. and R.M. Nesse. 1991. The dawn of Darwinian medicine. Quarterly Review of Biology 66:1-22.
Exactly so.
As I have said on many prior evolution threads, I am a Jew who believes that God created the heavens and the earth. I believe God did so by creating the basic forces of nature and setting them to work, knowing that they would be sufficient to accomplish the Divine plan. Darwinian theory doesn't require God, but nor does it exclude Him.
You left out the hexose monophosphate shunt. :)
I wonder what new chemical pathways they've found in those funky biota that hang out near the deep sea vents/chimneys.
Death throes. They know it's over. They are looking for a theory to replace darwinism but, until one comes along, it's either that or creation. Acknowledging a Creator, as our founding fathers did, is beneath their dignity so darwinism is defended against reason.
There's a new nightclub opening on the river that could use a good comedian.
IOW, there are none.
Acquired Resistance Bacteria can develop resistance to antibiotics, e.g. bacterial populations previously-sensitive to antibiotics become resistant. This type of resistance results from changes in the bacterial genome. Acquired resistance is driven by two genetic processes in bacteria: (1) mutation and selection (sometimes referred to as vertical evolution); (2) exchange of genes between strains and species (sometimes called horizontal evolution).
Vertical evolution is strictly a matter of Darwinian evolution driven by principles of natural selection: a spontaneous mutation in the bacterial chromosome imparts resistance to a member of the bacterial population. In the selective environment of the antibiotic, the wild type (non mutants) are killed and the resistant mutant is allowed to grow and flourish. The mutation rate for most bacterial genes is approximately 10-8. This means that if a bacterial population doubles from 108 cells to 2 x 108 cells, there is likely to be a mutant present for any given gene. Since bacteria grow to reach population densities far in excess of 109 cells, such a mutant could develop from a single generation during 15 minutes of growth.
Horizontal evolution is the acquisition of genes for resistance from another organism. For example, a streptomycete has a gene for resistance to streptomycin (its own antibiotic), but somehow that gene escapes and gets into E. coli or Shigella. Or, more likely, Some bacterium develops genetic resistance through the process of mutation and selection and then donates these genes to some other bacterium through one of several processes for genetic exchange that exist in bacteria.
Bacteria are able to exchange genes in nature by three processes: conjugation, transduction and transformation. Conjugation involves cell-to-cell contact as DNA crosses a sex pilus from donor to recipient. During transduction, a virus transfers the genes between mating bacteria. In transformation, DNA is acquired directly from the environment, having been released from another cell. Genetic recombination can follow the transfer of DNA from one cell to another leading to the emergence of a new genotype (recombinant). It is common for DNA to be transferred as plasmids between mating bacteria. Since bacteria usually develop their genes for drug resistance on plasmids (called resistance transfer factors, or RTFs), they are able to spread drug resistance to other strains and species during genetic exchange processes.
The combined effects of fast growth rates, high concentrations of cells, genetic processes of mutation and selection, and the ability to exchange genes, account for the extraordinary rates of adaptation and evolution that can be observed in the bacteria. For these reasons bacterial adaptation (resistance) to the antibiotic environment seems to take place very rapidly in evolutionary time: bacteria evolve fast!
Proof is no part of science. I can't provide proof the sun will rise tomorrw, but I have every confidence it will, and I would argue it trivializes faith to claim that it requires faith to say so.
jc... (( original ))
"They have no business encouraging homosexuality, or forcing its acceptance upon students or faculty. The schools should teach the kids to behave like civilized people, that every individual should be treated with respect. Instead, they choose to indoctrinate them in leftist ideology. The entire school should be a safe zone for everyone. The whole idea of special protection for any one group is unAmerican."
4 posted on 01/26/2003 3:07 PM PST by Jeff Chandler ( ; -)
fC... (( revision ))
They have no business encouraging homosexuality (( evolutuion // atheism // . . . abortion // link )) **, or forcing its acceptance upon students or faculty. The schools should teach the kids to behave (( think )) ** like civilized people, that every individual should be treated with respect. Instead, they choose to indoctrinate them in (( hard core )) ** leftist ideology (PC // BIAS )) ** . The entire school should be a safe zone (( NO brainwashing )) ** for everyone. The whole idea (( tyranny )) ** of special protection (( MONOPOLY )) ** for any one group (( priveledges )) ** is . . . unAmerican (( original thread )) - - - (( forced RELIGION establishment // vetting // witch hunts // purges // elites )) ** .
.. .. .. **...my additions !
Yes, I had all this in undergrad and med school.
However, expression of latent genes and or gene swapping IS NOT EVOLUTION!
Its simply expression of pre-existing DNA code.
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