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Blue-eyed humans have a single, common ancestor
University of Copenhagen ^ | January 30, 2008 | Unknown

Posted on 01/30/2008 2:10:37 PM PST by decimon

New research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today. What is the genetic mutation

“Originally, we all had brown eyes”, said Professor Eiberg from the Department of Cellular and Molecular Medicine. “But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a “switch”, which literally “turned off” the ability to produce brown eyes”. The OCA2 gene codes for the so-called P protein, which is involved in the production of melanin, the pigment that gives colour to our hair, eyes and skin. The “switch”, which is located in the gene adjacent to OCA2 does not, however, turn off the gene entirely, but rather limits its action to reducing the production of melanin in the iris – effectively “diluting” brown eyes to blue. The switch’s effect on OCA2 is very specific therefore. If the OCA2 gene had been completely destroyed or turned off, human beings would be without melanin in their hair, eyes or skin colour – a condition known as albinism. Limited genetic variation

Variation in the colour of the eyes from brown to green can all be explained by the amount of melanin in the iris, but blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes. “From this we can conclude that all blue-eyed individuals are linked to the same ancestor,” says Professor Eiberg. “They have all inherited the same switch at exactly the same spot in their DNA.” Brown-eyed individuals, by contrast, have considerable individual variation in the area of their DNA that controls melanin production.

Professor Eiberg and his team examined mitochondrial DNA and compared the eye colour of blue-eyed individuals in countries as diverse as Jordan, Denmark and Turkey. His findings are the latest in a decade of genetic research, which began in 1996, when Professor Eiberg first implicated the OCA2 gene as being responsible for eye colour. Nature shuffles our genes

The mutation of brown eyes to blue represents neither a positive nor a negative mutation. It is one of several mutations such as hair colour, baldness, freckles and beauty spots, which neither increases nor reduces a human’s chance of survival. As Professor Eiberg says, “it simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”


TOPICS: Culture/Society; Miscellaneous; News/Current Events; Technical
KEYWORDS: blueeyes; eugenics; evolution; genetic; genetics; godsgravesglyphs; helixmakemineadouble; incest; mutation
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To: decimon

I have eyes that are described as hazel. Somethimes they are gray, sometimes green, and sometimes blue.

Any info on this changing of color would be appreciated. (I’m too lazy to look it up)


261 posted on 01/31/2008 4:50:10 PM PST by wildbill
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To: chickpundit

Maybe my eyes were brown when I was younger as well, people told me they were brown. When I was about 35 I was looking at my eyes very closely in a mirror and I said “guess what? my eyes are green with brown centers”. I never thought that they might have changed.


262 posted on 01/31/2008 4:50:22 PM PST by Ditter
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To: wildbill
I have eyes that are described as hazel. Somethimes they are gray, sometimes green, and sometimes blue.

Any info on this changing of color would be appreciated. (I’m too lazy to look it up)

I think that's just a matter of lighting and how deep set your eyes are.

263 posted on 01/31/2008 4:54:15 PM PST by decimon
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To: decimon

Could it be the clothes I wear giving off some kind of reflection?

I notice the colors change more with the color of my clothes but I didn’t want to say that our front lest someone call me crazy.


264 posted on 01/31/2008 4:58:53 PM PST by wildbill
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To: wildbill
Could it be the clothes I wear giving off some kind of reflection?

I guess. That could go along with the lighting.

I was thinking more of degrees of sunlight, fluorescent lighting versus incandescent lighting...stuff like that.

265 posted on 01/31/2008 5:08:49 PM PST by decimon
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To: mamelukesabre

Well the link at the end is what I have found that best describes, to what degree it can,on what I have learned on eye colors and there coding. While semantically you are arguing the density of melanin, I am trying to say that you are specifically coded for your eye color, be it blue, green or polka dotted. Not saying that the color blue or the color green is created, but that your genes are saying produce x and x amount of melanin, which determines the color of your eyes.(BTW blood vessels behind the eyes are red, which is why albinos have red eyes because they have no melanin, while blue eyes do have some melanin but like the sky you only see blue)

http://www.athro.com/evo/gen/geframe.html


266 posted on 01/31/2008 5:38:47 PM PST by aft_lizard (born conservative...I chose to be a republican)
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To: aft_lizard

Oxygenated blood is red. De-oxygenated blood is blue. In earth’s atmosphere, you will never see de-oxygenated blood outside the body. As soon as blood is in contact with air, it oxygenates.


267 posted on 01/31/2008 7:42:58 PM PST by mamelukesabre
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To: fishtank
Where do gray eyes fall in this spectrum? Lots of Russians and Slavs have gray eyes.
268 posted on 01/31/2008 9:48:49 PM PST by Ciexyz
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To: Lady Jag

Um, clear?


269 posted on 02/01/2008 5:20:05 AM PST by fanfan ("We don't start fights my friends, but we finish them, and never leave until our work is done."PMSH)
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To: TheThirdRuffian
That’s the funniest thing I have ever read.

Damn Canadians.

Sure, go ahead and laugh.
I’m afraid to check my mail today.

;-)

270 posted on 02/01/2008 5:22:48 AM PST by fanfan ("We don't start fights my friends, but we finish them, and never leave until our work is done."PMSH)
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To: blam
When we go to Thailand in a couple of days, We are going to try a visit to Cave Lodge and Ban Rai Rock Shelter. This seems to go from recent times "Iron Age" back to the time period of Sundaland. I figures I should try befor I get too crippled up.
271 posted on 02/01/2008 10:39:32 AM PST by JimSEA
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To: JimSEA

Looks interesting. Good luck and stay out of trouble over there.


272 posted on 02/01/2008 10:41:53 AM PST by blam (Secure the border and enforce the law)
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To: decimon

OK, my siblings and I are all blue eyed. WHO is our common ancestor? I’m claiming Adam...


273 posted on 02/01/2008 10:47:51 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: rfp1234

Uh, oh, my oldest grandson looks like Putin...


274 posted on 02/01/2008 10:48:58 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: blam

My father had lovely cornflower blue eyes. We’re all blue eyed but not as bright and beautiful as his were.


275 posted on 02/01/2008 10:50:27 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: weegee

I’ve got my eye on you...


276 posted on 02/01/2008 10:50:57 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: TheThirdRuffian

My dad had blue eyes, mom’s were more hazel. We’re all blue eyed blonds.


277 posted on 02/01/2008 10:53:57 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: GoLightly

Yes they did! Raping and pillaging their way around France, Ireland, America...


278 posted on 02/01/2008 10:57:16 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: Ditter

I dunno. Do you bark and eat your food out of a dish on the kitchen floor???


279 posted on 02/01/2008 11:05:16 AM PST by Marysecretary (GOD IS STILL IN CONTROL.)
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To: Marysecretary
Yes they did! Raping and pillaging their way around France, Ireland, America...

Germany, England, Scotland, Iberia, Northern Africa, Rome, Sicily, Naples, Russia, Ukraine, Byzantium...

280 posted on 02/01/2008 11:10:09 AM PST by GoLightly
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