Posted on 10/20/2021 12:10:44 PM PDT by bitt
AMBRIDGE, Mass. — A revolutionary cancer treatment is combining several therapies to successfully destroy tumors, scientists from the Massachusetts Institute of Technology say. Their breakthrough treatment “jump starts” a patient’s natural defenses by merging chemotherapy, immunotherapy, and tumor-fighting techniques.
Using this novel approach, researchers say diseased cells are removed from the body, treated with drugs, and then placed back in the tumor. They are delivered with a payload of medications that activate the immune system’s T cells. The injured cancer cells appear to act as a distress signal that spurs them into action.
“When you create cells that have DNA damage but are not killed, under certain conditions those live, injured cells can send a signal that awakens the immune system,” says senior author Professor Michael Yaffe in a university release.
An effective cancer treatment for many types
Immunotherapy – which stimulates the immune system to kill tumors – only works for a handful of cancers. The new method could enable it to be used against many forms of the disease.
In experiments, it completely eliminated tumors, melanomas, and breast cancers in 40 percent of treated mice. When the same rodents were injected with cancer cells months later, T cells recognized and destroyed them before new tumors could form.
The MIT team improved the performance of immunotherapy drugs called checkpoint blockade inhibitors. They take the brakes off of T cells that have become “exhausted” and unable to attack tumors. Adding chemotherapy drugs helped injured cells send signals that attract the immune system’s attention.
“This describes a new concept of immunogenic cell injury rather than immunogenic cell death for cancer treatment,” Prof. Yaffe reports.
“We showed that if you treated tumor cells in a dish, when you injected them back directly into the tumor and gave checkpoint blockade inhibitors, the live, injured cells were the ones that reawaken the immune system.”
Several clinical trials combining the therapies are underway. The study in the journal Science Signaling sheds fresh light on the best approach.
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GREAT NEWS!!!!................................................
Can we injure some RINO’s, stick them back into the Republican party and see if it cures it?
great news- but wonder if it can be used with folks with overactive immune systems already?
At one point they were trying to inhibit LDH since cancers can feed on it.
That would require the Republican Party rise from the dead.
bookmark
Maybe the way to reveal that a cure exists, is to "discover" it again, publicly this time.
Can it cure baldness? Name your price.
Isn’t it strange that drug companies are now coming out with cancer cures after a dog de-wormer (not hydroxychloroquine or ivermectin), wipes out most cancers. I am not plugging some product or supplement. But I can’t come out and tell you what it is because Big Pharma will “CANCEL” it immediately. I checked with my independent pharmacy and it costs like $400, but a friend has been buying it for about $25 for his 80-year old father who has his stage 4 cancers in full remission.
Hint: Go to My Cancer Story dot rocks
Good point and maybe people with overactive immune systems are less likely to get cancer?
Overactive immune systems seem to be the next biggest issue on the diseases list. Lots of diseases tied to immune system issues.
There is a very rare disorder called LDH deficiency.
They should be tracking those people to see if it keeps the cancer gene from turning on since cancer feeds on it
What could possibly go wrong?
It seems as though fewer and fewer think our way.
Oh well, I welcome the zombie apocalypse...
There is already a cure for baldness; it involves removing some plasma and treating it with something, then re-infusing it. Dermatologists do it. Probably Bosley, too. It’s ‘spensive, as you might expect.
Someone claimed that we will get cancer if we live long enough. The reason why we may never know it is because our immune system kicks in and kills it.
It is a fact that a weakened immune system increases your risk of getting cancer.
My uncle had RA and, I wasn't able to confirm, but I believe that they were treating him with immunosupressive drugs. He died of a very aggressive form of brain cancer.
[One of the QAnon/8Chan conspiracies floating around in 2016 was that there has been a cure for cancer for years and years, and Trump was going to reveal it.
Maybe the way to reveal that a cure exists, is to “discover” it again, publicly this time.]
Wouldn’t be surprising to me. There’s no money to be made in cures. Only extensive Rx treatments.
Just like the Wu-Flu vaccine. It doesn’t cure you or protect you from getting infected. Yet they continue to push it in the name of “science”....
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