Molnupiravir ©
Take the Red Pill ©
Active Ingredients
- Ivermectin 18mg
- Doxycycline 100mg
- Elemental Zinc 300mg
- Vitamin D3 10000iu
Posted on 10/07/2021 6:32:18 AM PDT by Red Badger
Merck’s new ‘not Ivermectin’ Covid-19 treatment, molnupiravir, costs $17.74 to produce – yet the company is charging the US government $712 for the treatment – a 40x markup, according to The Intercept, citing a report issued last week by the Harvard School of Public Health and King’s College Hospital in London.
The pill, originally developed using US government funds as a possible treatment for Venezuelan equine encephalitis, cut the risk of hospitalization and death in half in a randomized trial of 775 adults with mild/moderate Covid who were considered at high risk for disease due to comorbidities such as obesity, diabetes and heart disease. The trial was stopped early so the company could apply for and emergency use authorization (EUA). The drug did not benefit patients who were already hospitalized with severe disease.
News of the oral ‘wonder drug’ sent shares of Merck higher last week, as the company says it can deliver 10MM doses by the end of the year.
Clearly, the pill could bring in massive profits to Merck and its partner on the drug, Ridgeback Biotherapeutics – which licensed the drug from Emory University in 2020 and then sold the worldwide rights to the drug to Merck for a sum which has not been disclosed.
Meanwhile, the Defense Threat Reduction Agency, a division of the Department of Defense, funded development of the drug by Emory University to the tune of $10 million between 2013 and 2015, according to nonprofit group Knowledge Ecology International discovered.
DTRA-JSTO, under the CBDP, invested in a broad-spectrum #antiviral, leading to the discovery of molnupiravir through collaborative research with @Merck, @EmoryUniversity, #RidgebackBio, & @NIH.
This drug has applications against encephalitic alphaviruses, flu, SARS-CoV2, & more. pic.twitter.com/Z9gztSreC2
— Defense Threat Reduction Agency (@doddtra) October 1, 2021
Yet, as Quartz points out, only Merck and Ridgeback will profit from the new antiviral – which they say “could be one of the most lucrative drugs ever,” bringing in as much as $7 billion by the end of this year alone.
Despite its initial investment, the U.S. government seems to be facing a steep markup in prices. In June, the government signed a $1.2 billion contract with Merck to supply 1.7 million courses of the medication at the $712 price. The transaction is due to take place as soon as molnupiravir receives emergency use authorization from the Food and Drug Administration.
Good government advocates are pointing out that because federal agencies spent at least $29 million on the drug’s development, the government has the obligation to ensure that the medicine is affordable. “The public funded this drug, and therefore the public has some rights, including the rights you have it available under reasonable terms,” said Luis Gil Abinader, senior researcher at Knowledge Ecology International. -The Intercept
Pushing back
Ridgeback co-founder Wendy Holman told CNBC in an interview last week that they asked for, but “never got government funding” for the manufacture of molnupiravir. The company also claimed in a press release touting the study that “since licensed by Ridgeback, all funds used for the development of molnupiravir have been provided by Merck and by Wayne and Wendy Holman of Ridgeback.”
Critics, meanwhile, say the $700+ price point is absurd – with health advocates concerned that people some countries will not be able to afford the new drug.
“Offering someone a $700 treatment when they don’t yet feel that ill is going to mean that a lot of people are not going to take it,” said King’s College Hospital physician Dzintars Gotham, co-author of the report – which suggests that Merck would still reap a 10% profit margin if they priced molnupiravir at $19.99.
“If you can’t afford medicine because it’s 1,000 times more than you can afford, or because it’s 100 times more than you can afford, it doesn’t matter,” said Melissa Barber, a doctoral candidate at the Harvard School of Public Health and co-author of the report on molnupiravir, adding “those are both bad.”
Barber and Gotham acknowledge that the $17.74 cost of producing a five-day course of the antiviral pills is an estimate but said that the algorithm they used, and have employed to estimate the production costs for hundreds of drugs, tends to result in overestimates in the long run.
Meanwhile, the prices that private companies charge for drugs tend to go up rather than down. “For all these deals that have happened for therapeutics or vaccines, the price has only increased as uncertainty has decreased,” she said. “One price is given and then, for the next sale, the price goes up. The price went up for other drugs and vaccines, so I would be very surprised if this price didn’t go up, too.” -The Intercept
If only there were another option for mild-moderate Covid-19 cases that was inexpensive and used around the world for decades with an extremely positive drug safety profile.
We’re just going to leave this here (as we noted last month):
Widely prescribed anti-parasitic Ivermectin (also made by Merck) has shown massive efficacy worldwide in the treatment of mild and moderate cases of Covid-19, plus as a prophylactic. India’s Uttar Pradesh province, with a population of over 200 million, says that widespread early use of Ivermectin ‘helped keep positivity [and] deaths low.’
(source, May 12th) Separately, there have been several studies funded by the Indian government, primarily conducted through their largest govt. public medical university (AIIMS).
Role of ivermectin in the prevention of SARS-CoV-2 infection among healthcare workers in India: A matched case-control study (source) Conclusion: Two-dose ivermectin prophylaxis at a dose of 300 μg/kg with a gap of 72 hours was associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers for the following month.
Ivermectin as a potential treatment for mild to moderate COVID-19 – A double blind randomized placebo-controlled trial (source) Conclusion: There was no difference in the primary outcome i.e. negative RT-PCR status on day 6 of admission with the use of ivermectin. However, a significantly higher proportion of patients were discharged alive from the hospital when they received ivermectin.
Clinical Research Report Ivermectin in combination with doxycycline for treating COVID-19 symptoms: a randomized trial (source, double-blind randomized, peer-reviewed) Discussion: In the present study, patients with mild or moderate COVID-19 infection treated with ivermectin in combination with doxycycline generally recovered 2 days earlier than those treated with placebo. The proportion of patients responding within 7 days of treatment was significantly higher in the treatment group than in the placebo group. The proportions of patients who remained symptomatic after 12 days of illness and who experienced disease progression were significantly lower in the treatment group than in the placebo group.
Here are more human studies from other countries on the ‘horse dewormer’: Peru: Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in Peru in Close Time Conjunction, State-By-State, with Ivermectin Treatments (source, peer-reviewed, University of Toronto, Universidad EAFIT) For the 24 states with early IVM treatment (and Lima), excess deaths dropped 59% (25%) at +30 days and 75% (25%) at +45 days after day of peak deaths. Case fatalities likewise dropped sharply in all states but Lima
Spain: The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial (source, University of Barcelona, peer-reviewed) Findings: Patients in the ivermectin group recovered earlier from hyposmia/anosmia (76 vs 158 patient-days; p < 0.001).
Bengladesh:
A Comparative Study on Ivermectin-Doxycycline and Hydroxychloroquine-Azithromycin Therapy on COVID-19 Patients (source – peer reviewed, though not govt funded) Conclusion: According to our study, the Ivermectin-Doxycycline combination therapy has better symptomatic relief, shortened recovery duration, fewer adverse effects, and superior patient compliance compared to the Hydroxychloroquine-Azithromycin combination. Based on this study’s outcomes, the Ivermectin-Doxycycline combination is a superior choice for treating patients with mild to moderate COVID-19 disease.
A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness (source, peer-reviewed double blind randomized, though small sample size) Discussion: A 5-day course of ivermectin resulted in an earlier clearance of the virus compared to placebo (p = 0.005), thus indicating that early intervention with this agent may limit viral replication within the host. In the 5-day ivermectin group, there was a significant drop in CRP and LDH by day 7, which are indicators of disease severity.
Meanwhile, There are currently 76 ongoing or completed clinical trials on Ivermectin around the world. Below are the results of 32 which have been completed. One can visit ivermeta.com and dig down on any of these / read the entire study. The site recommends Ivermectin in conjunction with vaccines to confer the best protection against Covid-19, however we’ll leave that to you and your doctor to discuss.
Screenshot, http://ivermeta.com/ Perhaps those who can’t pony up $700 will seek other options. (ORIGINAL)
um... what it costs to “produce” is irrelevant. How many billions did it cost for the research to invent it? And how many other billions were spent on other failed research?
Buy Merck, don’t buy Merck.
Decisions, decisions.
So now the Left wants to require their own horse pills.
Yes, and how many years are left on the patent?
> How many billions did it cost for the research to invent it? And how many other billions were spent on other failed research? <
Bingo. There is greed in the pharmaceutical industry. That’s for sure. But here’s something that many people don’t understand. If you restrict a drug company’s chance to make a profit, you are also restricting the development of important new drugs.
Merck created ivermectin. But you see, it is inexpensive. Once you know that you understand why.
um... a division of the Department of Defense, funded development of the drug...
“ treatment for Venezuelan equine encephalitis,”
Equine ? So it’s basically “horse paste” by another name so they can charge whatever they want for it. This just validates Ivermectin as the correct treatment for COVID !
Hey. No fair reading the article.
As Freepers, we are entitled to jump to incorrect conclusions.
As a general rule, the public is ignorant of what makes a business run. There are several misguided souls here that illustrate that every day.
Oh the irony, it's so thick it hurts...
IverMercktin
It’s different.
I recently doubled stocked up on better meds for under $200. Meds that have been proven to work many times over and have been around for a very long time so any side effects are known. Nothing noteworthy.
We have no idea what these new drugs are all about just like we know nothing about the long term effects of the death clot shot. For all we know it has some of the same ingredients which taken over time equal the same thing as getting the clot shot that may or may not kill, sterilize, maim, ruin a heart, damage any or all organs or many other things we simply don’t know about yet.
The Medical Industrial Complex isn’t even trying to hide the evil anymore.
You, um, do realize that it was taxpayers' money that paid for the research that led to the development of molnupiravir in the first place, don't you? That's how this sh*t pretty much works nowadays.
Educate yourself people.
When I was a young pharmacist (years ago) I had absolute trust in the research and business ethics of Merck, Pfizer, Lilly, Glaxo etc.
They are no longer the ethical companies they once were. They are devoid of ethics. Their research is tainted with intentional errors of omission. They have become a political creature at the administrative level.
THEY LIE!
Resident Biden, aka ‘the Big Guy’ has to get his 10%, plus Hunter Biden gets his cut, Then Fauci gets his cut .....
Just consider it Biden’s ‘luxury tax’ on health.
Stores that over charge for supplies during a storm as an example can be fined and the owners arrested for gouging.
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