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Implant boosts activity in injured brain - Deep-brain stimulation offers hope for minimally...
Nature ^ | 1 August 2007 | Michael Hopkin

Posted on 08/01/2007 7:00:10 PM PDT by neverdem

Deep-brain stimulation offers hope for minimally conscious patients.

CLEVELAND CLINIC
Deep-brain stimulation might help trauma patients regain consciousness.

Brain function has been improved in a patient who was in a minimally conscious state, by electrically stimulating a specific brain region with implanted electrodes. The achievement raises questions about the treatment of other patients who have been in this condition for years, the researchers say.

Patients in a minimally conscious state, often the result of severe brain trauma, show only intermittent evidence of awareness of the world around them. Typically, they are assumed to have little chance of further recovery if they show no improvement during their initial 12-month rehabilitation programme.

In the latest case study, neuroscientists describe how they implanted electrodes in the brain of a 38-year-old man who had been in a minimally conscious state for more than six years following a serious assault. By electrically stimulating a brain region called the central thalamus, they were able to help him name objects on request, make precise hand gestures, and chew food without the aid of a feeding tube (see page 600). The thalamus is involved in motor control, arousal and in relaying sensory signals — from the visual systems, for example — to the cerebral cortex, the part of the brain involved in consciousness.

Nicholas Schiff of Weill Cornell Medical College in New York, and his colleagues chose the patient because they believed his condititon was due to impairment of the arousal system, and that despite considerable damage to his cerebral cortex, many essential areas were preserved.

"There will be a subset of patients who are responsive to this approach," says Schiff. But he adds that patients with different brain injuries may not benefit from electrostimulation. "Not every patient in a minimally conscious state will fit this profile," Schiff says, and it is difficult for neurologists to identify those patients who will show recovery.

Nevertheless, the case shows that many patients currently seen as beyond hope of rehabilitation might benefit from the results of further research. "Severe brain injury is not an uncommon problem, and the number of people doing research on this is shockingly small," Schiff says. "It's very rare to find a programme that will take a patient in a minimally conscious state even straight out of acute care. If they don't respond in a lively enough way and can't communicate and interact with people at the bedside, they go to a nursing home directly."

"The report does not suggest that deep-brain stimulation [DBS] 'cures' the minimally conscious state," says Paul Matthews, a clinical neuroscientist at Imperial College, London. "Although based on a study of only a single patient, it suggests that DBS may be adapted to benefit at least some patients in the minimally conscious state. And it emphasizes that improvements can be made by patients even long after an injury.

"Although we do not know precisely which brain connections are important, we may expect that some specific connections must be intact for DBS to have a beneficial effect."


TOPICS: Culture/Society; Extended News; News/Current Events
KEYWORDS: braingate; dbs; deepbrainstimulation; health; neuroscience; science
Nature 448, 522 (2 August 2007) | doi:10.1038/448522a; Published online 1 August 2007
1 posted on 08/01/2007 7:00:11 PM PDT by neverdem
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To: neverdem

Maybe Tim Johnson is a good candidate for this...


2 posted on 08/01/2007 7:02:40 PM PDT by Farmer Dean (That was a hell of a thing!)
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To: neverdem
I know a girl who had implants that help stimulate my brain. Great medical breakthrough....awsome in fact
3 posted on 08/01/2007 7:05:48 PM PDT by DainBramage
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Comment #4 Removed by Moderator

To: DainBramage

somehow I doubt your brain was stimulated into writing PhD papers about quantum mechanics or existentialism


5 posted on 08/01/2007 7:28:37 PM PDT by ari-freedom (Never attribute to malice that which is adequately explained by stupidity.)
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To: neverdem

Wonderful news for many families that have a loved one in such a state.

Hopefully they will be able to expand on this, and help these people rejoin ‘life’.


6 posted on 08/01/2007 7:48:26 PM PDT by Shadowstrike (Be polite, Be professional, but have a plan to kill everyone you meet.)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Brown clouds boost global warming - Aerosols over Asia incriminated in Himalayan glacial

New risks discovered for HPV (under fingernails)

FReepmail me if you want on or off my health and science ping list.

7 posted on 08/01/2007 9:34:57 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: neverdem; AdmSmith; Berosus; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; ...

Thanks ND.

I wonder if it would work on Ted Kennedy, “Cut and Run” Murtha, Harry Reid, Nancy Pelosi, or Michael Moore?


8 posted on 08/01/2007 9:43:31 PM PDT by SunkenCiv (Profile updated Tuesday, July 31, 2007. https://secure.freerepublic.com/donate/)
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To: neverdem

Gee I wonder if this technology was used on Terry Shivio {sp?}, what we may have learned about her actual condition?


9 posted on 08/01/2007 9:44:08 PM PDT by The Chief
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To: neverdem
"DBS may be adapted to benefit at least some patients in the minimally conscious state."

I was looking to see what funding DARPA has in this, but found little. The implications for tweaking this into behavior modification or into the anticipated brain-machine interface are great.

(I instantly thought of democrats, specifically that photo of Terizzah "crazy" Kerry)


10 posted on 08/01/2007 9:48:35 PM PDT by endthematrix (He was shouting 'Allah!' but I didn't hear that. It just sounded like a lot of crap to me.)
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To: SunkenCiv

Sorry, this is about Consciousness, not CONSCIENCE.


11 posted on 08/01/2007 9:54:27 PM PDT by The Spirit Of Allegiance (Public Employees: Honor Your Oaths! Defend the Constitution from Enemies--Foreign and Domestic!)
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To: SunkenCiv

Brain-injured man speaks after 6 years
AP via Yahoo ^ | 8/1/2007 | MALCOLM RITTER

Posted on 08/01/2007 11:00:27 AM PDT by ElkGroveDan

http://www.freerepublic.com/focus/f-news/1874825/posts


12 posted on 08/01/2007 10:00:01 PM PDT by Fred Nerks (Fair dinkum!)
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To: The Spirit Of Allegiance

Good point.


13 posted on 08/01/2007 10:20:50 PM PDT by SunkenCiv (Profile updated Tuesday, July 31, 2007. https://secure.freerepublic.com/donate/)
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To: The Chief

My thoughts exactly!

I still mourn Terry Schiavo’s cruel death.


14 posted on 08/01/2007 11:10:07 PM PDT by Fawnn (Canteen wOOhOO Consultant and tshirtcollections.com person - Faith makes things possible, not easy.)
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To: 8mmMauser

Ping...


15 posted on 08/01/2007 11:13:56 PM PDT by TheSarce
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To: DainBramage

16 posted on 08/01/2007 11:34:07 PM PDT by Gondring (I'll give up my right to die when hell freezes over my dead body!)
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To: neverdem; TheSarce
Pinged from Terri Dailies

8mm


17 posted on 08/02/2007 4:16:51 AM PDT by 8mmMauser (Jezu ufam tobie...Jesus I trust in Thee)
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To: neverdem

Thanks for posting. Very interesting. My mom had DBS implants for relief from Parkinson. Very positive results for minimizing tremor.


18 posted on 08/02/2007 5:29:39 AM PDT by PGalt
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