Mutation found that cures heart disease

djf, with references

[djf]

In 1980, a man from a small town called Limone Sul Garda in northern Italy went to a doctor for some problem, not heart related.



Testing of his blood showed very high levels of triglycerides, and very low levels of HDL, the good form of cholesterol. By all rights, the man should have either been dead from, or in imminent danger of a heart attack.

But his arteries were clear.
Analysis of his blood showed he had a very special form of Lipoprotein, a type of HDL. And further work with this particular type of Lipoprotein revealed astounding results.

In some of the initial small scale tests of this form of HDL, volunteers were given one shot a week of it, for a trial that lasted five weeks.

Measurements of the blockage in their arteries showed that total blockage was reduced by 4% in five weeks. While this may not sound like much, to a cardiologist, it's equivalent to taking years off of your cardiac age.

Further testing and analysis with animals show fantastic results. While standard HDL's are desirable, this substance has been shown to for all intents and purposes, to completely reverse heart disease.

Various articles have referred to it as "Drano for the arteries".

Research is continuing with a slightly modified, bioengineered form and results are extremely promising.

The cholesterol (and yes, it is cholesterol) that is saving these people's lives is called ApoA-Milano.

And of the forty or fifty people in that tiny Italian town, all descended from a man born in 1760, a man who had a small change in his genes, not a single one has yet to die from heart disease!


http://www.lbl.gov/Science-Articles/Archive/LSD-Milano-Bielicki.html
http://www.usatoday.com/news/health/2006-01-08-heart-disease-cover_x.htm
http://jama.ama-assn.org/cgi/content/abstract/290/17/2292

There are 96 references on PubMed for apoa milano

[Appalled but Not Surprised]

What are you saying? That I should smile and grin when someone suggests that the "genepool is getting polluted"? Doesn't that imply that the "genepool needs to be cleaned up"?

Remember Auschwitz started when some drunken German in a bar in 1919 started blaming the Jews. The time to nip evil is in the bud.

[FairOpinion]

Important medical discovery ping.

[FairOpinion]

More detail in here, one of the links supplied with the original post:

http://www.usatoday.com/news/health/2006-01-08-heart-disease-cover_x.htm

[djf]

I was wondering about that. Why, then, if I get my cholesterol measured, do they break it into ldl's and hdl's?

According to some of the literature I read, there are only 18 known natural forms of cholesterol.

Cholesterol isn't really the bad guy anyways. It's the oxidation and irritation of the arteries. The cholesterol is the "patch".

BTW, I do have high cholesterol, but my hdl/ldl is pretty good.

[stylin19a]

We let Downes Syndrome people have children also.

Who is "We" ?

[goodnesswins]

I think starfish was just stating a "fact." NOT saying we should take any action....sheesh.

[goodnesswins]

Check your CRP (C-Reactive Protein)....that COULD matter more than cholesterol

[aposiopetic]

I was wondering about that. Why, then, if I get my cholesterol measured, do they break it into ldl's and hdl's?

Exactly. The predictive value of the concentrations and ratios is where it's at.

BTW, I do have high cholesterol, but my hdl/ldl is pretty good.

Congrats on the ratio. Keep up the good work.

[He Rides A White Horse]

Our gene pool becomes weaker and weaker, as the years go by, as we "save" those who would have died 100 years ago....and THEY have children.

Waiting, to cut out the deadwood.
Waiting, to clean up the city.
Waiting, to follow the worms.
Waiting, to put on a black shirt.
Waiting, to weed out the weaklings.
Waiting, to smash in their windows and kick in their doors.
Waiting, for the final solution to strengthen the strain.
Waiting, to follow the worms.
Waiting, to turn on the showers and fire the ovens.

[ForGod'sSake]

Methuselah would not be impressed ;' )

Thanks for the ping.

[Squantos]

FYI

[diverteach]

Various articles have referred to it as "Drano for the arteries".

There already is and has been "Drano for the arteries", it's called EDTA. Something most doctors pretty much hold as a secret amongst themselves. If the public knew of it and used it, there big money cardio business would suffer greatly.

Essentially it's a low grade acid that enters the bloodstream and slowly disolves away the plaque build-up in the arteries.

http://www.townsendletter.com/Chelation/chelation_glassman.htm

[narby]

Interesting article.

[Cacique]

BTT for latrer read

[PatrickHenry]

Yes, interesting. Not really for the ping list, however. More of a medical thing.

[Stellar Dendrite]

Ping

[philetus]

Scientific arrogance is commonplace. Physicians consider themselves to be experts in their own field. If a majority of physicians do not endorse a new therapy, they collectively rely on public recognition of their own "expertise" to discount a new concept that they themselves have not yet embraced. They forget that all great advances in medicine began with a small minority. Their thinking tends to follow along these lines: "If I'm the expert and I don't use this new therapy and if my many colleagues and peers are experts and they don't believe in the new therapy, then we must be right and that small group of physicians who believe differently must be wrong. We're the experts."

http://drcranton.com/chelation/carter.htm

[Stellar Dendrite]

they need this for cancer as well

[Stellar Dendrite]

i mean this type of discovery

[djf]

I mentioned EDTA on a previous thread a while back and got absolutely pounded for it.

Even though a quick search on PubMed shows hundreds of studies that show it has positive effects on blood pressure, and helps with blood flow to the lowere extremities, etc. The evidence is pretty overwhelming that EDTA works.