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Darwin's greatest challenge tackled
European Molecular Biology Laboratory ^ | 10/28/2004 | EMBL

Posted on 11/03/2004 5:11:47 PM PST by general_re

Darwin's greatest challenge tackled
The mystery of eye evolution

Researchers provide concrete evidence about how the human eye evolved

When Darwin's skeptics attack his theory of evolution, they often focus on the eye. Darwin himself confessed that it was 'absurd' to propose that the human eye, an 'organ of extreme perfection and complication' evolved through spontaneous mutation and natural selection. But he also reasoned that "if numerous gradations from a simple and imperfect eye to one complex and perfect can be shown to exist" then this difficulty should be overcome. Scientists at the European Molecular Biology Laboratory [EMBL] have now tackled Darwin's major challenge in an evolutionary study published this week in the journal Science. They have elucidated the evolutionary origin of the human eye.

Researchers in the laboratories of Detlev Arendt and Jochen Wittbrodt have discovered that the light-sensitive cells of our eyes, the rods and cones, are of unexpected evolutionary origin ­ they come from an ancient population of light-sensitive cells that were initially located in the brain.

"It is not surprising that cells of human eyes come from the brain. We still have light-sensitive cells in our brains today which detect light and influence our daily rhythms of activity," explains Wittbrodt. "Quite possibly, the human eye has originated from light-sensitive cells in the brain. Only later in evolution would such brain cells have relocated into an eye and gained the potential to confer vision."

The scientists discovered that two types of light-sensitive cells existed in our early animal ancestors: rhabdomeric and ciliary. In most animals, rhabdomeric cells became part of the eyes, and ciliary cells remained embedded in the brain. But the evolution of the human eye is peculiar ­ it is the ciliary cells that were recruited for vision which eventually gave rise to the rods and cones of the retina.

So how did EMBL researchers finally trace the evolution of the eye?

By studying a 'living fossil,' Platynereis dumerilii, a marine worm that still resembles early ancestors that lived up to 600 million years ago. Arendt had seen pictures of this worm's brain taken by researcher Adriaan Dorresteijn [University of Mainz, Germany]. "When I saw these pictures, I noticed that the shape of the cells in the worm’s brain resembled the rods and cones in the human eye. I was immediately intrigued by the idea that both of these light-sensitive cells may have the same evolutionary origin."

To test this hypothesis, Arendt and Wittbrodt used a new tool for today’s evolutionary biologists – 'molecular fingerprints'. Such a fingerprint is a unique combination of molecules that is found in a specific cell. He explains that if cells between species have matching molecular fingerprints, then the cells are very likely to share a common ancestor cell.

Scientist Kristin Tessmar-Raible provided the crucial evidence to support Arendt's hypothesis. With the help of EMBL researcher Heidi Snyman, she determined the molecular fingerprint of the cells in the worm's brain. She found an opsin, a light-sensitive molecule, in the worm that strikingly resembled the opsin in the vertebrate rods and cones. "When I saw this vertebrate-type molecule active in the cells of the Playtnereis brain – it was clear that these cells and the vertebrate rods and cones shared a molecular fingerprint. This was concrete evidence of common evolutionary origin. We had finally solved one of the big mysteries in human eye evolution."

Source Article
Ciliary photoreceptors with vertebrate-type opsins in an invertebrate brain.
D. Arendt, K. Tessmar-Raible, Snyman, Dorresteijn, J. Wittbrodt
Science. October 29, 2004.


TOPICS: Culture/Society; News/Current Events; Philosophy
KEYWORDS: crevolist; darwin; evolution; eye; sight
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To: general_re


The law of enthropy is readily observable. Everything tends to deteriorate to the most simple form. Macro evolution starts with a primeaval soup, and develops into more complex organisms. When we are born, we begin to die. Strength becomes weakness. Weakness becomes death. I am just wondering how evolution gets around this fact. Albert Einstein stated that he believed this was the one law that could never be gotten around.


101 posted on 11/07/2004 7:20:42 PM PST by Murp
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To: whattajoke

To believe what you believe makes the Apostle Paul seem to be an unbeliever. If you consider the randomness of purine and pyrimadine base sequences to have evolved identically and in such diverse environmental circumstances cannot be explained by logic, empiric observations, or by random chance. It is logical to therefore conclude it is an artilce of your faith. It is your constitutional right to believe such, but don't besmirch the honorable name of science by adfixing your fantasy to it. You choose self delusion. Your choice.


102 posted on 11/07/2004 7:22:16 PM PST by Texas Songwriter (Texas Songwriter)
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To: Dimensio

You must have a gastrointestinal pain or an itch.


103 posted on 11/07/2004 7:23:50 PM PST by Texas Songwriter (Texas Songwriter)
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To: O.C. - Old Cracker

After graduating with a degree in Biology and Chemistry, spending 3 years working on my masters degree in Pleistocene Paleontology (my dissertation was "Identification of Pleistocene Fossils for McFaddin Beach,Texas" , Obtaining my medical degree, and spending 5 years in a general surgical residency...After all that schooling I have concluded that you,sir, have made the most cogent statement in this entire thread. I wish all of our fellow freeper could have this assurrance. We must not give up on them.


104 posted on 11/07/2004 7:30:06 PM PST by Texas Songwriter (Texas Songwriter)
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To: Dimensio

Resurrection observed by more than 500 eyewitness. And they were not squid or octopus.


105 posted on 11/07/2004 7:31:41 PM PST by Texas Songwriter (Texas Songwriter)
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To: Murp

If you deny the 1st and 2nd laws of thermodynamics, then you can never get the first molecule or atom or subatomic particle produced. If the makeup of the universe has always been present the according to the 2nd law (entropy) it requires that all particle, subatomic elements would not defy the law of entropy and wouold therefore be washed out into a cosmic ocean of nothingness approaching absolute zero,completely vacuous. Unless.....something held it all together. SOMEONE not tied to the universe by cause and effect, SOMEONE separate and distinct from the universe, SOMEONE who is not tied to the universe by the 1st and 2nd Laws of thermodynamics, and can reach down into His universe with love(science), compassion(science?), redemption (science?), justice (science?), and forgiveness (science?)


106 posted on 11/07/2004 7:39:55 PM PST by Texas Songwriter (Texas Songwriter)
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To: Texas Songwriter
You must have a gastrointestinal pain or an itch.

I'm sure that in your mind this constitutes a stinging rebuttal, but in the mind of people who are capable of rational thought it is nothing more than a mindless non-sequitur.
107 posted on 11/07/2004 7:52:54 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: Texas Songwriter
Resurrection observed by more than 500 eyewitness.

So you assert. Do you have an independent account of each of these witnesses?
108 posted on 11/07/2004 7:53:19 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: Texas Songwriter
Not to put too fine a point on it, but you're so full of crap your eyebrows stink.

Do you actually have an argument to offer, or are you too arrogant to admit that you might be mistaken but too ignorant to actually present a reasoned response?

Your one liners thus far only demonstrate that you posess a stunning level of willful ignorance and irrational anger.
109 posted on 11/07/2004 7:54:21 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: general_re

Yes, now we are proving theories with other theories. I think a few thousand years ago they could prove turtles held up the earth by how slow the stars moved.


110 posted on 11/07/2004 7:56:59 PM PST by Casloy
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To: Murp
The law of enthropy is readily observable. Everything tends to deteriorate to the most simple form.

This is not the law of thermodynamics. In fact, this is in direct contradiction to observed life cycles of individual organisms that start from a merging of two simple cells and grow to a complex organism structure.

The problem here is not with evolution. The problem here is with your fundamental understanding (or lack thereof) of scientific principles.

Macro evolution starts with a primeaval soup,

No, it doesn't. Now you demonstrate your fundamental ignorance of evolution.

When we are born, we begin to die. Strength becomes weakness.

This is just incoherent babble that doesn't make any point whatsoever.

. I am just wondering how evolution gets around this fact.

Simple. Unlike what you just stated, evolution is not nonsense. Albert Einstein stated that he believed this was the one law that could never be gotten around.

Please, present his exact statement on the matter.
111 posted on 11/07/2004 7:57:21 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: Casloy
Yes, now we are proving theories with other theories.

No theory is ever proven.
112 posted on 11/07/2004 7:57:46 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: Dimensio

My point exactly.


113 posted on 11/07/2004 7:58:37 PM PST by Casloy
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To: O.C. - Old Cracker

"There is an absolute truth and His name is Jesus Christ of Nazareth."

The only Truth here. All else is conjecture and wishful thinking.

All that Creationists ask is that Evolution be taught as a theory not fact. Adding Creation into the classroom can bring a needed dose of humility to the impressionable minds.


114 posted on 11/07/2004 8:00:44 PM PST by eleni121 (NO more reaching out!)
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To: Dimensio

Yes, I do. Read Matthew,Mark,Luke, John. It's all right there. Where do you read your theological prescriptions?


115 posted on 11/07/2004 8:01:14 PM PST by Texas Songwriter (Texas Songwriter)
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To: Dimensio

Mr. Dimensio , please go back to origins and explain to me where I am wrong...with your own science. I am more than willing to have a discourse with you. Let me be your student. Convince me.


116 posted on 11/07/2004 8:03:14 PM PST by Texas Songwriter (Texas Songwriter)
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To: general_re
"Quite possibly, the human eye has originated from light-sensitive cells in the brain. Only later in evolution would such brain cells have relocated into an eye and gained the potential to confer vision."

There seems a lot of assumptions and conditions in those sentences.

These people are implying the ability of sight developed before fish, amphibians and insects branched off. Why termites?

117 posted on 11/07/2004 8:09:20 PM PST by Tribune7
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To: Dimensio

Mr. Dimensio, in rereading your remarks I focused on the phrase "rational thought". I wonder, can you explain to me from a scientific reference point, of course, what is thought,,,how do you measure it? where does it reside,,does it exist? I pontificate, can thought be "rational"? I do not mean these to be trite considerations. I am not angry so please dispense with that notion. In fact I am quiet elated , especially at the results of the past few days, as I am sure you are.


118 posted on 11/07/2004 8:10:55 PM PST by Texas Songwriter (Texas Songwriter)
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To: Murp

The second law applies only to closed systems - the earth is not a closed system. In order to decrease entropy, you apply energy, which we get from the big hot thing you see in the daytime sky. ;)


119 posted on 11/07/2004 8:12:42 PM PST by general_re (Drive offensively - the life you save may be your own.)
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To: Casloy

Inductive logic is your friend.


120 posted on 11/07/2004 8:13:31 PM PST by general_re (Drive offensively - the life you save may be your own.)
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