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The Pancreatic Cancer Paradox: How One Hidden Population Achieved the Impossible
JustusRHope.Substack ^ | January 3, 2026 | Justus R. Hope

Posted on 01/04/2026 6:09:13 AM PST by Twotone

Cancer doctors have grown accustomed to good news. Over the past three decades, lung cancer deaths have plummeted by 40%. Breast cancer mortality has dropped 44%. Prostate cancer deaths have fallen by half.

Colon cancer, once a leading killer, now claims 50% fewer lives than in 1990. These victories represent billions in research funding, surgical innovations, targeted therapies, and nationwide screening campaigns—the sum total of modern medicine’s war on cancer.

Yet one malignancy refuses to follow the script.

Pancreatic cancer—the silent executioner lurking behind the stomach, wrapped around vital blood vessels, often symptomless until the final act—is not only resisting our best efforts but advancing. Between 1999 and 2023, deaths surged 70%. By 2030, it will become America’s second-leading cancer killer. The five-year survival rate hovers at a grim 12%, virtually unchanged in fifty years. For most patients, the diagnosis equals a death sentence within six months.

(Excerpt) Read more at justusrhope.substack.com ...


TOPICS:
KEYWORDS: cancer; pancreatic; pancreaticcancer; substackloser; substacktroller
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A long article, but with some very interesting data...
1 posted on 01/04/2026 6:09:13 AM PST by Twotone
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To: Twotone

Yes. I received the article in my inbox yesterday.something to be paid attention to.


2 posted on 01/04/2026 6:11:20 AM PST by sauropod
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To: Twotone
Between 1999 and 2023, deaths surged 70%.

studying THAT should provide some clues ...
3 posted on 01/04/2026 6:16:57 AM PST by bankwalker (Feminists, like all Marxists, are ungrateful parasites.)
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To: Twotone

What is the punchline? What factors explain absence of pancreatic cancer? I could not read the last part.


4 posted on 01/04/2026 6:24:19 AM PST by nwrep
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To: Twotone

It points to crap water (sometimes literally) and obesity.

I would imagine the morbidly obese are “used” to gastric issues—and they would likely ignore the first signs.

Once it gets “bad”, and people notice, it is likely too late.

The pancreas is at the conjunction of your body’s blood and digestive superhighway. It spreads directly to the liver, stomach, and abdomen. And once it gets across those barriers, it is game over in most cases.

The diagnostic issue is that the pancreas’s is difficult to see through most traditional tools. In my wife’s case, they needed to do X-rays, CT Scans, Ultrasounds, and Endoscopic Ultrasounds. It wasn’t until the surgeon actually got into the pancreas that they could “stage” the tumor.

If they could come up with an inexpensive screen tool (targeting a CA19-9 factor in the blood) they would be able to diagnose early. But, morbidly obese people are going to trigger a bunch of false positives.

The biggest thing….is to be lucky.


5 posted on 01/04/2026 6:27:17 AM PST by Vermont Lt
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To: bankwalker

Reading the article, it looks like that is when people started to get really really fat and develop type ii diabetes in large scale. Fat people are much more likely to get pancreatic cancer.

Last I checked the islets of langerhans that control sugar are located in the pancreas.


6 posted on 01/04/2026 6:30:26 AM PST by TheThirdRuffian (Orange is the new brown)
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To: Twotone

What’s going on? There isn’t a place to comment on the thread that has this same excerpt..This is in the thread about the woman getting a payout from CTA in Chicago and murdering her landlady and dismembering her body...


7 posted on 01/04/2026 6:30:46 AM PST by Thank You Rush
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To: Twotone
Meanwhile, Alaska—with limited healthcare infrastructure, the nation’s highest smoking rates, and months of darkness—records the lowest pancreatic cancer mortality at 15.2 per 100,000.

Have they adjusted for high consumption of alcohol in cold places without sunshine for long period of time and without darkness for long periods of time?

8 posted on 01/04/2026 6:31:26 AM PST by AndyJackson
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To: Thank You Rush

https://freerepublic.com/focus/f-bloggers/4360348/posts

Excerpt in two different subjects - threads...


9 posted on 01/04/2026 6:32:52 AM PST by Thank You Rush
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To: Twotone

I’d say high fructose corn syrup intake ramped up in the 90s and continued. The pancreas has to deal with controlling sugar levels. So increased intake of a sugar that humans don’t have a long genetic blueprint for metabolizing puts the pancreas on overdrive. Will Type II diabetes rates map to these cancer rates?


10 posted on 01/04/2026 6:34:27 AM PST by EMI_Guy ("You have to slow down to go fast." - Kenny Robertsonn's)
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To: Twotone; PBRCat

Is this sock puppetry for thread starting or what would cause you two to have the same text body with different headlines?


11 posted on 01/04/2026 6:35:05 AM PST by IllumiNaughtyByNature (Polls are designed to sell more ads & polls only. If it's not a horse race the money dries up.)
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To: Twotone

This is a fascinating article. Thanks for posting. The fact that pancreatic cancer cases along the ‘industrial sewers’ of the Mississippi and Danube rivers mirror each other..is a revelation. Now we have another very definite cause.


12 posted on 01/04/2026 6:42:03 AM PST by libh8er
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To: IllumiNaughtyByNature

Something went wrong with the posting. I noticed that the verbiage from my article was in another article, & thought I’d made a mistake with the title. But when you click on the other article, the correct verbiage is there.

A mystery...


13 posted on 01/04/2026 6:44:53 AM PST by Twotone ( What's the difference between a politician & a flying pig? The letter "F.")
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To: libh8er

People are well advised to drink only RO water especially if they live along these rivers — and in general also cut down on lunch meats, a rich source of cancer causing nitrites.


14 posted on 01/04/2026 6:49:02 AM PST by libh8er
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To: nwrep

The punchline essentially is 1) make sure your drinking water is clean; 2) control your weight (avoid over-eating, try intermittent fasting); 3) make sure you avoid stress. Exercise isn’t as good as simply constructive movement, like gardening. Do things that make your body move, but don’t create more stress.

The avoidance of bad drinking water seems to be extremely important. Check where your water is coming from.


15 posted on 01/04/2026 6:53:29 AM PST by Twotone ( What's the difference between a politician & a flying pig? The letter "F.")
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To: Twotone

Did it explain why Rhode Island and Delaware had high rates?


16 posted on 01/04/2026 6:54:06 AM PST by Controlling Legal Authority (Author of “Are You Ready to Adopt?”)
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To: Twotone

Apparently pancreatic cancer can be difficult to detect until it is Stage 4. My husband’s doctor told us that particular type of cancer forms a matrix that protects the cancer itself from chemo and other treatments.

The doctors thought my husband had pancreatic cancer - turned out it was liver cancer - the doctors were relieved b/c liver cancer, although also deadly, is easier to treat.


17 posted on 01/04/2026 6:55:49 AM PST by Bon of Babble (You Say You Want a Revolution?)
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To: Controlling Legal Authority

Rhode Island and Delaware...I don’t see any specific comment, but would assume from the rest of the article it’s some form of water contamination.


18 posted on 01/04/2026 7:06:04 AM PST by Twotone ( What's the difference between a politician & a flying pig? The letter "F.")
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To: Twotone

I’m leaning toward microplastics...


19 posted on 01/04/2026 7:06:54 AM PST by matthew fuller (I designate Democrats and the Biden Criminal Family as Terrorist Organizations. Matthew Fuller)
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To: Twotone

REceived same article email ... the charts/graphics are great.


20 posted on 01/04/2026 7:07:02 AM PST by Jane Long (Jesus is Lord!)
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