Posted on 11/21/2025 5:40:18 PM PST by ConservativeMind
Scientists have uncovered how the gut microbiota help the immune system fight melanoma, explaining why patients with a fiber-rich diet and balanced gut bacteria tend to respond better to cancer immunotherapies.
The study shows that molecules produced by gut bacteria upon digestion of dietary fiber can improve the function of cancer-fighting immune cells. The research team found that these digestive by-products influence melanoma progression by naturally boosting killer T cell function in pre-clinical cancer models.
"Melanoma patients undergoing immunotherapy can benefit from a fiber-rich diet and previous studies suggested that what we eat affects the immune system. However, how that works wasn't clear," said Dr. Bachem.
"When gut bacteria break down dietary fiber and other nutrients, they produce small molecules called metabolites. In this study, we found that the process involved in the production of short-chain fatty acids, a type of metabolite, plays a key role in how cancer-fighting T cells function.
"These metabolites act like messengers and fuel—directing how T cells function and powering them with the necessary energy so that they can fight cancer more effectively."
"T cells can become exhausted and lose the ability to properly fight cancers. Our study showed that the microbiota-derived metabolites preserve the function of T cells and thereby improve their capacity to kill melanoma cells.
"This project began by us asking very fundamental questions about how killer T cells function. Once we identified how killer T cells responded to the microbiota-derived metabolites, it became obvious that resolving these fundamental questions about how T cells operate might also help understand why only some patients with melanoma respond effectively to immunotherapies," he said.
They applied their experimental findings to melanoma patients and discovered that the gut microbiome from advanced melanoma patients responding to immunotherapy also shows signs of increased short-chain fatty acid production.
(Excerpt) Read more at medicalxpress.com ...
Heard on the news that John Mellancamp’s daughter who had Stage 4 melanoma that had spread to brain says her cancer is gone
I find this hard to believe but if so people should be finding out her treatment
While I eat a high-fiber, low carb, low lectin diet with 16+ hours intermittent fasting, the pre-cancerous skin lesions I had remitted very quickly by consuming 8 apricot pits daily, boiled for 10 seconds and the skins removed.
Ivermectin paste applied to skin with cancer has been reported to work. I have used the common Ivermectin horse paste bought at my feed store.
What does boiling and removing the skins do, for the apricot seeds?
Thx.
I’ve read the same...testimonies of skin cancers completely disappearing after using the Ivm paste.
Wasn’t Laetrile apricot based? Seems it went no where after supposed efficacy. I believe Steve McQueen went to Mexico in a last ditched effort for Laetrile treatment. IIRC he had mesothelioma.
It’s been a long hard two weeks for me, and the proof of this is that I was trying to figure out how a microphone and a fiber-rich diet could work together against melanoma.
The skins of apricots and almonds contain lectins, proteins destructive to the intestinal lining and are commonly found in may seeds.
Leatrile is found in many plants, but is most concentrated in apricot seeds. I don't see it as a cancer treatment, but probably useful as a prophylactic supplement.
Her melanoma spread to her brain and she had about tumors and they surgically took most of them out then I think she had radiation. Not sure if she had more than that.
You can also boost short chain fatty acids on carnivore, without fiber.
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