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Intermittent fasting increases sex drive in male mice: An approach for low libido in humans? (One Meal A Day)
Medical Xpress / German Center for Neurodegenerative Diseases / Cell Metabolism ^ | March 28, 2025 | Dr. Dan Ehninger et al

Posted on 04/02/2025 4:01:39 PM PDT by ConservativeMind

Long-term fasting in 24-hour cycles increases the sex drive of male mice by lowering the concentration of the neurotransmitter serotonin in the brain. This effect is linked to a diet-induced deficiency of the precursor substance tryptophan—an amino acid that must be obtained through food.

Researchers suggest that similar mechanisms may exist in humans.

Starting at two months of age, male mice were subjected to a specific form of intermittent fasting. Their access to food followed a recurring 24-hour pattern: the animals were allowed to feed ad libitum for 24 hours, followed by 24 hours with access to water only.

During the 22-month fasting regimen, the males were housed together without any contact with females. They were later introduced to three-month-old females that had been raised without dietary restrictions.

Increased mating behavior was also observed in younger mice. These males had also started intermittent fasting at the age of two months, but had followed this diet for only six months before being introduced to females. They, too, were more sexually active than age-matched peers that had been fed ad libitum. However, the effect was absent in other experimental groups—both young and old—that fasted for only a few weeks.

"For intermittent fasting to increase sex drive, it takes some time," says Zhou. "Based on our experiments, the minimum duration appears to be somewhere between six weeks and six months."

Among the sexually active male mice, one factor stood out: serotonin—a chemical messenger generally associated with inhibitory effects—was present at unusually low levels.

"These mice were, so to speak, sexually uninhibited; the usual regulatory restraint was diminished," says Ehninger.

"All in all, the fasting mice consumed almost 15% fewer calories than the animals in the control group. This also roughly applies to their intake of tryptophan," says Zhou.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: fasting; omad
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One Meal A Day intermittent fasting on a constant basis might just make you a bit “uninhibited,” no matter the age.

Elon?

1 posted on 04/02/2025 4:01:39 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/02/2025 4:02:10 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

The way to a mouse’s heart is through his stomach.


3 posted on 04/02/2025 4:03:54 PM PDT by Hieronymus ( )
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To: ConservativeMind

So if I start fasting, I’ll have the hots for Minnie Mouse?


4 posted on 04/02/2025 4:05:05 PM PDT by PJ-Comix (Yes, I am the Toxic Troll Terminator)
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To: ConservativeMind

At my age, I don’t dare test this theory.


5 posted on 04/02/2025 4:05:10 PM PDT by ComputerGuy ( )
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To: ConservativeMind

I’m very suspicious of the idea that there is any animal model for the human that can be used in every respect; especially when human psychology is involved.


6 posted on 04/02/2025 4:06:30 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: ConservativeMind

That’s baloney. Act like a man.

You’re better to eat a giant meal, something like a Tony Soprano size bowl of spaghetti, chicken fried steak and mashed potatoes and gravy, or maybe a giant steak with a loaded baked potato and Texas toast. Wash it all down with copious amounts of beer.
Stay up really late before heading into the boudoir. Before you do take a dip in the hot tub with the object of your affection to lower the man’s blood pressure super low, and so you are both nice and squeaky clean like Adam and Eve.
Hit yourself with a load of Viagra that would stop the heart of a rhinoceros.

Then give the maiden your best... and fall into a deep restful sleep/coma.


7 posted on 04/02/2025 4:08:56 PM PDT by DesertRhino (2016 Star Wars, 2020 The Empire Strikes Back, 2025... RETURN OF THE JEDI...)
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To: ConservativeMind

Lots of sex requires lots of food, eggs are good for sex refueling.


8 posted on 04/02/2025 4:10:06 PM PDT by ansel12 ((NATO warrior under Reagan, and RA under Nixon, bemoaning the pro-Russians from Vietnam to Ukraine.))
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To: ConservativeMind

Transfer mice from the cocaine studies lab?


9 posted on 04/02/2025 4:11:35 PM PDT by know.your.why
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To: ConservativeMind

I’ve been an intermittent and extended faster for 6 years now. Anytime I shed a few pounds of the fat I’ve been storing for decades, there is definitely a “hey baby” effect.

My PCP says it’s because the fat stores a lot of hormones that are then released into the wild. Fun times.


10 posted on 04/02/2025 4:11:54 PM PDT by Valpal1 (Not even the police are safe from the police!!!)
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To: hellinahandcart

*cough*


11 posted on 04/02/2025 4:19:29 PM PDT by sauropod (Make sure Satan has to climb over a lot of Scripture to get to you. John MacArthur Ne supra crepidam)
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To: ConservativeMind

Lola Beedoe - I met her once, she was no fun.


12 posted on 04/02/2025 4:19:32 PM PDT by Magic Fingers (Political correctness mutates in order to remain virulent.)
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To: ConservativeMind

I’ve been doing fasting from 6 pm on Sunday until 6 pm on Thursday. Water only.

On Monday I want to eat badly.

On Tuesday hunger starts to go away.

On Wednesday on I have little if no appetite.

I usually don’t remember my dreams but on Wednesday night I start to. I don’t need to sleep much and my energy and mental acuity really spike.

On Thursday I’m not hungry and I feel like I can go without food forever. I’ve basically been a page at a glance reader since 2nd grade. In fact, I have had a reading addiction all my life. That gets worse during a fast but I like it.

During all of this I am doing cardio for 45 minutes a day and free weights for 2 hours a day. I’m basically one big muscle, my arms are very big and it’s not unusual for a female to grab my bicep randomly if I’m in a bar. As far as libido things are in order, most Saturdays are what I call “cousins night” when a couple of friends visit. Wink wink — nod nod.

Females usually think that I’m 45-50 and I am, 20 years ago. Lol. Best time of my life right now, especially seeing the crooks and thieves getting theirs and knowing that that insect Kamala isn’t stealing the country into the ground.

Long live the alpha males! Go Trump! Go Musk!


13 posted on 04/02/2025 4:32:00 PM PDT by isthisnickcool (UD" )
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To: Valpal1
My PCP says it’s because the fat stores a lot of hormones that are then released into the wild.

It also stores a lot of fat-soluble environmental toxins that get released into the wild when you fast, too.

I have been dabbling in water/intermittent fasting for... a few years. I always do pretty well then just all of sudden forget I am supposed to be fasting for a few months. Just started an alternate-day fasting schedule yesterday. Just skipping one day of eating has me feeling a lot better.

14 posted on 04/02/2025 4:32:22 PM PDT by E. Pluribus Unum (Democrats are the Party of anger, hate and violence.)
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To: ConservativeMind

Regular old air with N, CO2 and O plus other traces at 700 ft above sea level seems to do it for me.


15 posted on 04/02/2025 4:34:36 PM PDT by Theophilus (covfefe)
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To: ConservativeMind

Since they’re fasting, do they then kill and eat their partner after they have sex like a female praying mantis might do?


16 posted on 04/02/2025 4:45:33 PM PDT by mass55th (“Courage is being scared to death, but saddling up anyway.” ― John Wayne)
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To: ConservativeMind

Rumor has it, this theory was the original theme for John Steinbeck’s short story “ Of Mice and Men”, but the idea was too farfetched for any publisher to accept his manuscript. So, John changed the story completely, keeping nothing but the title. ////(sarc)


17 posted on 04/02/2025 4:59:57 PM PDT by lee martell
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To: Hieronymus

LOL. My Mama told me that one, substituting a man for a mouse, many many moons ago. I took it to heart and landed me a keeper.


18 posted on 04/02/2025 7:02:31 PM PDT by FamiliarFace (I got my own way of livin' But everything gets done With a southern accent Where I come from. TPetty)
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To: ConservativeMind

More JUNK science.


19 posted on 04/02/2025 8:37:16 PM PDT by OrangeHoof (Thank you, Trump, Musk, Leavitt....)
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To: ConservativeMind

Well, i suppose if you are hungry enough, you will eat just about anything.


20 posted on 04/02/2025 8:52:54 PM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will)
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