Posted on 03/20/2025 8:49:48 AM PDT by Red Badger
A jaw-dropping 96% of sufferers were vitamin D deficient—could this simple fix be the key to relief for millions of people?
The study titled, Efficacy of vitamin D replacement therapy on 28 cases of myalgic encephalomyelitis/chronic fatigue syndrome after COVID-19 vaccination, was recently published in Nutrition:
Background
Prolonged symptoms have been reported following both COVID-19 infection and vaccination, with some cases leading to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Of 80 patients presenting to our hospital with postvaccination syndrome, 28 met the diagnostic criteria for ME/CFS. We conducted a retrospective study on these 28 patients.
Methods
We measured serum 25-hydroxyvitamin D levels in 28 patients who developed ME/CFS after COVID-19 vaccination between August 2022 and February 2024. Vitamin D replacement therapy included dietary counseling, sun exposure recommendations, and oral vitamin D supplementation. We evaluated changes in blood vitamin D levels and symptom improvement.
Results
At initial visit, 27 of 28 patients diagnosed with ME/CFS had insufficient or deficient serum 25-hydroxyvitamin D levels (16 ± 4 ng/mL, mean ± SD). Following vitamin D replacement therapy, we observed an increase in blood vitamin D levels (28 ± 5 ng/mL) associated with a decrease in ME/CFS diagnostic symptoms (from 10.3 ± 2.1 to 3.3 ± 2.0). Notably, 23 of 28 patients (82%) no longer met ME/CFS diagnostic criteria after the therapy. Among the symptoms, sleep problems showed the most improvement (71%), followed by autonomic symptoms (68%).
Conclusions
For patients developing ME/CFS after COVID-19 vaccination with insufficient or deficient vitamin D levels, appropriate vitamin D replacement therapy under medical guidance may lead to symptomatic relief. We are preparing a randomized controlled trial to evaluate the efficacy of vitamin D replacement therapy in individuals with ME/CFS who have developed vitamin D deficiency following COVID-19 infection or vaccination.
Here are the key findings:
High Prevalence of Vitamin D Deficiency in Post-COVID-19 Vaccination ME/CFS Cases
27 out of 28 patients (96%) had insufficient or deficient vitamin D levels before treatment.
Mean baseline vitamin D level: 16 ± 4 ng/mL (deficient range).
Vitamin D deficiency may be linked to immune dysfunction and post-vaccine complications.
COVID-19 Vaccine Identified as a Major Suspected Trigger
68% of patients developed ME/CFS symptoms immediately after receiving a COVID-19 vaccine.
The onset of ME/CFS symptoms occurred after 1–6 doses of the vaccine, with the most cases appearing after the third dose (46%).
82% of patients had no history of prior COVID-19 infection, suggesting vaccination—not infection— was the primary trigger.
Some patients faced medical gaslighting, as previous doctors dismissed their post-vaccine symptoms.
Due to suspected vaccine-induced ME/CFS, patients were advised not to receive further COVID-19 booster shots.
Significant Symptom Improvement After Vitamin D Therapy
82% (23 out of 28) of patients no longer met ME/CFS diagnostic criteria following vitamin D replacement.
Most improved symptoms:
Sleep problems (71% improvement)
Autonomic symptoms (68% improvement)
Post-exertional malaise (54% improvement)
Pathologic fatigue showed the least improvement (21%), suggesting deeper systemic dysfunction in post-vaccine ME/CFS.
Vitamin D has also demonstrated potential therapeutic benefits for other adverse events following COVID-19 vaccination. Notably, Tsang et al reported that vitamin D protects against COVID-19 mRNA vaccine-induced myocarditis.
Given the growing evidence of vitamin D’s role in mitigating post-vaccine complications, large- scale, double-blind, placebo-controlled trials are urgently needed to further evaluate its efficacy in treating COVID-19 vaccine injury syndromes.
Ping!.....................
Bloodwork shows my D level in the 80’s and I’m feeling pretty darn good.
D3, Zinc, and C since Covid started. Never vax’d and never sick.
I take it daily. Doctor was going to tell me about K2 and was surprised when I said I already take it.
PING!
circle back for distribution
thanx for posting, red badger
circle back?
Jen Psaki izzat you?....................😁
But make sure you take the best one:
Nothing metabolizes D like oil. MCT or Olive is best. Taking before oily foods like salmon increases absorption even more.
My bride and I -- this old guy is 77, and avoids telling his wife's age -- blithely coasted through the mania and media hysteria of the Covid years, in part as we regularly take sun while gardening and beach going, and with D among the supplements we've taken for years. No sniffles, cold flu or the dreaded "take one for the team" BS mung which washed over this nation for some time.
Last doctor visit showed my D count to be very low. Since then I’ve been taking about 4000iu a day and feel much better. And with more energy. This article is legit.
bkmk
“Nothing metabolizes D like oil. MCT or Olive is best. Taking before oily foods like salmon increases absorption even more.”
Pinoresinol of olive oil decreases vitamin D intestinal absorption
The presence of polyphenols in the olive oil supplemented with DHA inhibited vitamin D postprandial response in rats (-25%, p<0.05). Similar results were obtained with a mix of the 3 polyphenols delivered to Caco-2 cells. However, this inhibitory effect was due to the presence of pinoresinol only.
https://pubmed.ncbi.nlm.nih.gov/27041321/
Interesting. I see Bluebonnet uses MCT oil, not olive oil like many other brands. Perhaps this is why.
I was feeling lethargic and lack energy last winter when I took my annual physical with my PA.
She tested out my Vitamin D level and found my level at 6,
and immediately prescribed Vitamin D for me to take.
My understanding through reading is that K2 enhances the absorption of Vitamin D, making it more effective.
I was aware of Vitamin D possible issues during the winter time
but didn't realize the need for sunshine in areas north of the Mason-Dixon line
since we spend most of the winter time indoors.
To be healthy, take off your clothes and get outdoors in the mid day sun ;-)
I take Vitamin D3 + K2 every single day.
Lots of osteoporosis in my family - just had a scan and there is a .8% chance that I will break my hip bones in the next 10 years so there may be something to it.
Sister had her bloodwork done for Vitamin D and it came back as 0%. Doctor immediately put her on daily infusions - wasn’t working so now she has the infusions (at home) twice a day.
Low levels of D have also been linked to cancers.
My one regret with Covid was getting on that bandwagon too late. Been doing it ever since, with the addition of an aspirin a day — and feel wonderful. I still get sick, but almost everything I catch is twenty-fours or less instead of the “laid up for a week” usual.
I had been feeling ‘ho hum’ lately, lethargic and just not wanting to do much. My dr ran some bloodwork and found I was quite Vitamin D deficient. He prescribed 50,000 units/1 per week and in about 3 days I was almost giddy with happiness, back to my old self. You can get smaller doses over the counter if need be.
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