Posted on 01/16/2025 7:14:24 PM PST by ConservativeMind
Researchers have identified a gut bacterium that may be associated with reduced dietary sugar intake. The findings, which are based on analyses of humans and mice, could aid the development of therapies to manage obesity and metabolic diseases, such as type 2 diabetes.
Animals are biologically hardwired to crave sugars, but unmanaged sugar preference can lead to high sugar intake, resulting in high blood glucose and increased risk of metabolic diseases. Previous research suggests that our cravings for different foods originate from signals sent to the brain from the gut, a key organ in transmitting dietary preferences. However, the regulation of sugar cravings is a complex process, and the role of gut microbes is unclear.
Xinmiao Liang and colleagues analyzed the blood of 18 mice with induced diabetes and 60 patients with type 2 diabetes and compared them with healthy controls (including 24 human controls). They found that diabetic mice and humans had reduced levels of FFAR4 in the blood, a protein that activates the secretion of GLP-1 (a hormone that regulates blood sugar and appetite).
The researchers observed that lower levels of FFAR4 in mice were associated with a higher preference for sugar. They also found that reduced levels of FFAR4 decreased the intestinal abundance of the gut microbe Bacteroides vulgatus and its metabolite pantothenate.
In mouse models, Zhu and colleagues found that pantothenate was responsible for the secretion of GLP-1 and subsequent secretion of FGF21, a liver hormone that acts directly on the hypothalamus, which is the brain region that controls feeding behavior. They verified this complex gut–liver–brain connection by feeding diabetic mice pantothenate or colonizing them with B. vulgatus, which were both found to significantly decrease their sugar-seeking behavior.
(Excerpt) Read more at medicalxpress.com ...
However, pantothenate is Vitamin B5. Either of these help people reduce sugar intake desire.
I need a bottle of that gut bacterium for wifey! when I stock Reeses white chocolate, butterfingers, baby Ruth, and Twix big packs in the freezer I get two from each and she gets six or right. it’s not fair! I should at least get as many as she does. but bacterium for her would be helpful. just sayin’.
Will B5 be ok to take after removal of the gallbladder?
Not once is the bacterium named.
Eat yogurt.
Not once is the bacterium named.
The excerpt says:
They also found that reduced levels of FFAR4 decreased the intestinal abundance of the gut microbe Bacteroides vulgatus and its metabolite pantothenate.
Yes. It is an essential vitamin.
Ty. Missed it.
It’s putting the cart before the horse. Obesity screws up the gut, because of the massive carbohydrate intake. When scientists want to grow Bacteria in a Petri dish, they feed it Sugar. Same thing in the gut. The “bad” bugs love carbs and sugar and dominate.
Put the damn fork down, reduce food intake to barely at or above the basal metabolic rate and the body will do what it was created or adapted to do - burn through the carbs, then starts on the fat, and thus lose the excess poundage. Starve the little bastards out. Everybody wants to take a pill or some quick and easy fix.
“Acid Reflux” is another good un. Left unchecked, it will erode the esophagus. But it doesn’t ordinarily require a pill. Oftentimes People eat so much goddamn food it starts backing up while asleep it isn’t any more complicated than that. “What could it be!?”
Cats aren't! Eagles aren't! Sharks aren't! Crocodiles...
Regards,
My Dr. told told me that Diet & Exercise would cure my Erectile Dysfunction.
If I could only get my wife to Diet & Exercise! 😁
Pantothenate is known to curb blood sugar response to stress, physical or mental. And stress can cause sugar cravings. So using pantothenate to reduce sugar cravings makes sense.
Bacterioides seems to be good for a lot of stuff.
HAHHAHAHA. Man that is a good one.
In all seriousness, dieting for a lean physique and hard physical training makes a man rock hard, if you catch my drift.
My wife told me to get something to cure my Erectile Dysfunction.
So I did. Her name is Cindy and she is 29. 😁
Good to know.
Go to your room! You are SO grounded.
Thank you for your reply. Much appreciated and I will read more about this.
People with intense sugar cravings can sometimes be vulnerable to alcoholism, such as Irish or Native American-descended people. In cases where someone does not drink alcohol for religious or ethical reasons (such as myself, raised by teetotalers), they may still have the alcoholism gene, and will “use” sugar as their adrenaline-stimulating drug of choice.
I could stand to be healthier and lose a few pounds in a natural way by taking the proper water-soluble vitamins for whatever is chemically responsible for my intractable sweet tooth. Thanks for this post. This advice is well worth trying.
4 am
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