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An affordable and effective nutritional approach to help reduce inflammation and prevent type 2 diabetes
Medical Xpress / University of Montreal / Scientific Reports ^ | Dec. 2, 2024 | Valérie Lamantia et al

Posted on 12/03/2024 3:13:59 PM PST by ConservativeMind

A team sheds new light on the role of marine-source omega-3 supplementation in treating adipose tissue inflammation and reducing the risk for cardiometabolic diseases like type 2 diabetes.

The study reveals that subjects with high numbers of blood low density lipoproteins (LDL)—commonly known as "bad cholesterol"—have higher inflammation in their adipose tissue than those with low LDL. The team also demonstrated that, in subjects with high blood LDL, adipose tissue inflammation was associated with abnormalities in carbohydrate (sugar) and fat metabolism that increase the risk for type 2 diabetes.

Furthermore, the study revealed that fish-oil omega-3 supplementation was effective in inhibiting the effects of LDL on adipose tissue inflammation and its association to risk factors for type 2 diabetes and cardiovascular disease. Omega-3 supplementation also improved the anomalies in carbohydrate and fat metabolism in all subjects.

To understand how LDL and omega-3 impact the risk of developing type 2 diabetes, Dr. Faraj's team recruited 40 healthy volunteers for a clinical study between 2013 and 2019. Of these, 33 volunteers completed a 12-week intervention with omega-3 supplementation providing 2.7 g of EPA and DHA in fish-oil per day. This dose of EPA and DHA is within the range recommended for supplementation by Health Canada.

The Faraj team found that EPA and DHA supplementation:

—Improved the body's secretion of insulin in response to increased blood glucose and its clearance of blood fat after a high-fat meal.

—Hindered subjects' LDL ability to trigger inflammation in their own adipose tissue.

—Eliminated the link between adipose tissue inflammation induced by LDL, or other metabolic and microbial inflammatory triggers, with several risk factors for type 2 diabetes and cardiovascular diseases.

—The higher were the levels of EPA and DHA in the blood, the better was the treatment of the cardiometabolic risk factors.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: diabetes; insulin; ldl; omega3
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To: ConservativeMind

I will probably add an algae-based Omega-3 product to my current plant-based “balanced Omega 3-6-9” supplement. The current supplement does lower triglycerides considerably but I have no other metrics to compare.


21 posted on 12/03/2024 6:55:08 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: steve86

I have always been a little worried about heavy metals in other marine sources — especially accumulation over the long term — but the algae sources are not subject to this.


22 posted on 12/03/2024 6:56:57 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ProtectOurFreedom

Your comments are a little fishy today.

Are you aware of whether krill-oil based supplements accrue the potential heavy metal accumulation issue, or are they tested and processed to obviate that concern?


23 posted on 12/03/2024 7:05:36 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ProtectOurFreedom
I found this:

Krill oil supplements generally have a lower risk of contamination with heavy metals compared to other marine oils, such as fish oil. This is because krill are lower on the food chain, which reduces the accumulation of toxins like mercury, arsenic, and PCBs. Additionally, many krill oil supplements undergo purification processes that are specifically designed to remove contaminants.

24 posted on 12/03/2024 7:55:45 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: steve86

Thanks, Steve. I had forgotten that benefit. The main reason I started on Krill oil is no fish burps. Every time I tried fish oil I got awful fish burps — yuck!


25 posted on 12/03/2024 7:57:15 PM PST by ProtectOurFreedom (“Facts can be ignored, but their consequences cannot be escaped” -- Thomas Sowell)
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To: ProtectOurFreedom

ChatGPT nearly had me talked into adding Schizochytrium-based Omega-3 supplements (algae type), but think I will go with krill oil for now. Yes, that is the real name of a type of algae!


26 posted on 12/03/2024 8:14:29 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: steve86

LOL...I’d be afraid to try anything named “Schizochytrium.”


27 posted on 12/03/2024 8:34:41 PM PST by ProtectOurFreedom (“Facts can be ignored, but their consequences cannot be escaped” -- Thomas Sowell)
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To: caver

Carlson we’re talking about is a very expensive brand of Norwegian Cod Liver Oil.
The best.


28 posted on 12/03/2024 9:14:21 PM PST by Veto! (Kamalala Sucks Rocks)
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To: JesusIsLord

According to most recent studies, whoever paid for the study is telling the truth.


29 posted on 12/03/2024 10:17:43 PM PST by gnarledmaw (Hivemind liberals worship leaders, sovereign conservatives select servants.)
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To: ConservativeMind

bump for reference


30 posted on 12/03/2024 10:55:08 PM PST by Robert357
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To: gnarledmaw
... whoever paid for the study is telling the truth.

I believe you're onto something! LOL!

31 posted on 12/04/2024 2:58:59 AM PST by JesusIsLord
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To: ConservativeMind

I have tried Fish oil. Probably too high a dose when I did. 3 different brands turned my urine red so I called it off. Fighting chronic pain for a while I have tried a lot of stuff. Willing to start trying again but I forgot all of these figures and things about it. Got a new hip a few months ago and that settled my back fusion down quite a bit. Like all of us, just looking for a few answers before life kills me.

Thanks for the health posts.


32 posted on 12/04/2024 8:52:59 AM PST by Delta 21 (If anyone is treasonous, it is those who call me such.)
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To: Veto!

Thank you!


33 posted on 12/04/2024 8:58:15 AM PST by caver ( )
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To: ConservativeMind

Thanks.


34 posted on 12/04/2024 11:26:28 AM PST by SharpRightTurn (“Giving money & power to government is like giving whiskey & car keys to teenage boys” P.J. O’Rourke)
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To: Delta 21

Happy to hear your back feels better. May you live long and thrive.

As for “fish” oil, a lot of it is truly terrible stuff. A few of us on this thread buy Carlson’s Norwegian Cod Liver Oil. Pricey but the very best quality. Perhaps you can buy a small bottle to see whether it helps you. It comes in liquid and capsule form, available at Natural Grocer here in town, a national chain that may have a branch near you. And of course AMZ has it.


35 posted on 12/04/2024 4:17:51 PM PST by Veto! (Kamalala Sucks Rocks)
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To: Jane Long

Thanks for the link. I will give Carlson a try.


36 posted on 12/06/2024 8:39:50 AM PST by KittyKares
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