Posted on 11/30/2024 2:44:28 PM PST by ConservativeMind
Results from a randomized, phase 2 clinical trial show that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months.
"The results were so strong in showing the benefit of this therapy for patient survival that we were able to stop the trial early."
In the study, 34 patients with stage 4 metastatic pancreatic cancer were randomized to receive either standard chemotherapy (gemcitabine and nab-paclitaxel), or chemotherapy plus infusions of high-dose vitamin C. The results showed that average overall survival was 16 months for the patients receiving the chemotherapy plus vitamin C, compared to eight months for the patients getting just chemotherapy. In addition, progression free survival was extended from four months to six months.
"Not only does it increase overall survival, but the patients seem to feel better with the treatment," Cullen says. "They have fewer side effects, and appear to be able to tolerate more treatment, and we've seen that in other trials, too."
Earlier this year, the results of another UI phase 2 clinical trial in patients with glioblastoma, a deadly form of brain cancer, were published. That study also showed a significant increase in survival when high-dose, IV vitamin C was added to standard of care chemotherapy and radiation.
A third phase 2 trial in non-small cell lung cancer is still underway, with results expected within the year.
Cullen says. "In one of our phase 1 trials for pancreatic cancer, where we combined high-dose, IV vitamin C with radiation, we still have three long-term survivors. They're out nine years at this point, which is far beyond the typical survival range."
(Excerpt) Read more at medicalxpress.com ...
Yes, it is one of those ascorbate, but I don’t remember if it’s Ca or Mg.
“Vitamin C, Titrating To Bowel Tolerance, etc.” by Robert F. Cathcart, M.D.
OrthoMed ^ | 1981 | Robert F. Cathcart
Posted on 1/14/2013, 6:34:19 AM by fishtank
VITAMIN C, TITRATING TO BOWEL TOLERANCE, ANASCORBEMIA, AND ACUTE INDUCED SCURVY
Robert F. Cathcart, III, M.D. Allergy, Environmental, and Orthomolecular Medicine 127 Second Street, Los Altos, California 94022, USA Telephone 650-949-2822
Probably it was Calcium Ascorbate.
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