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Nuclei in human cells breached by innovative nanopillars
New Atlas ^ | October 03, 2024 | Michael Franco

Posted on 10/03/2024 9:18:00 AM PDT by Red Badger

Scanning electron microscope image of a cell sitting atop the nanopillars

In a move akin to puncturing an egg yolk without breaking the shell or egg white, researchers have figured out how to pierce the nucleus of a cell without hurting the rest of the structure. The breakthrough could be big news for medical treatments.

To achieve this medical magic trick, researchers at the University of San Diego created an array of nanopillars which looks something like a microscopic bed of blunt nails. They then placed a variety of cells treated with a fluorescent dye on top of the pillars and watched what happened. The cells included heart muscle cells, skin cells, and fibroblasts, cells involved in developing connective tissue in our bodies.

All of the cells settled down around the pillars, which caused their nuclei to curve. This caused openings to form in the nuclear membrane but not in the exterior cellular structure as witnessed by the appearance of the dye from the nuclei showing up in the cell's cytoplasm. The openings in the nuclear membrane were self-healing and repaired themselves once removed from the array.

โ€œThis is exciting because we can selectively create these tiny breaches in the nuclear membrane to access the nucleus directly, while leaving the rest of the cell intact,โ€ said Zeinab Jahed, senior author of the study.

That's not an easy task to accomplish because the nuclear membrane is a notoriously tough shield that protects our genetic code. It can usually only be penetrated by certain molecules or by a needle that runs the risk of damaging the entire cell. Having a non-destructive way to open cellular nuclei can go a long way toward advancing gene therapy or sorting out ways to deliver drugs directly into the hearts of our cells.

(Excerpt) Read more at newatlas.com ...


TOPICS: Health/Medicine; Military/Veterans; Science; Society
KEYWORDS:
MORE TECHNICAL DATA HERE:

https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202410035


1 posted on 10/03/2024 9:18:00 AM PDT by Red Badger
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To: Red Badger

such conspiracy-thoerizing disinformation.


2 posted on 10/03/2024 9:22:28 AM PDT by xoxox
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To: xoxox
nuclear deformation, old school.


3 posted on 10/03/2024 9:24:53 AM PDT by xoxox
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To: xoxox
Whew!! For a moment, I thought the headline read:
"Nuclei in human cells breached by innovative CATERPILLARS."
Rest easy there, POF.
4 posted on 10/03/2024 9:37:15 AM PDT by ProtectOurFreedom (May the soy boys, feminazis, and alphabet weirdos choke on the toxic fumes of our masculinity)
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To: Red Badger

5 posted on 10/03/2024 9:41:48 AM PDT by PLMerite ("They say that we were Cold Warriors. Yes, and a bloody good show, too. ๐Ÿ˜ " - Robert Conquest )
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To: PLMerite

Looks like one of those District 9 guys


6 posted on 10/03/2024 10:34:04 AM PDT by NonValueAdded (What is the cost of lies?)
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To: xoxox

Gee! What could go wrong? Anybody’s guess.


7 posted on 10/03/2024 11:03:25 AM PDT by Parmy
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To: Red Badger

Humanity will possibly come to regret these “advances”. The evil/delusional “smart” humans will probably not feel regret, but rather delight.


8 posted on 10/03/2024 1:27:42 PM PDT by catbertz
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To: catbertz

You can be sure the sponsors won’t be signing up to be guinea pigs for this “treatment”.


9 posted on 10/04/2024 2:15:16 PM PDT by AustinBill (consequence is what makes our choices real)
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