Posted on 09/28/2024 9:03:36 PM PDT by ConservativeMind
Researchers have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans and can slow the onset of paralysis associated with the formation of amyloid plaques in a model of Alzheimer's disease.
Specifically, increases in longevity of between 10% and 18.6% and decreases in the proteotoxic effect of plaques of between 30% and 40% were observed.
The studies tested pure phytoene and extracts rich in this carotenoid obtained from microalgae.
According to Dr. Paula Mapelli Brahm, "These are very exciting preliminary results, so we are looking for funding to continue this line of research and to find out by what mechanisms these effects are produced."
Caenorhabditis elegans is a widely used animal model in biomedicine. In fact, it has been instrumental in important discoveries that have been recognized with the Nobel Prize, such as programmed cell death, RNA interference and applications of the GFP protein.
Professor Antonio Jesús Meléndez Martínez's team has spent 15 years studying phytoene, which is found in foods such as tomatoes, carrots, apricots, red peppers, oranges, mandarins and passion fruit, among others. It is a compound that is efficiently absorbed and found in many tissues, including the skin, where studies indicate that it can protect against ultraviolet radiation.
(Excerpt) Read more at medicalxpress.com ...
When I read the news of this to my nematode Caenorhabditis elegans, they were overjoyed.
Looks like the tablets are inexpensive: $0.04 ea in the 600 tablet container.
If it’s only one nematode, you should have said “it,” not “they.”
“Looks like the tablets are inexpensive: $0.04 ea in the 600 tablet container”
Two months supply, as 10 pills a day is the recommendation. Active ingredient in 10 tablets 240 mcg. take with food.
The powdered version is $8 more, 75 servings per container @ 1 teaspoon. 1 teaspoon gas 360 mcg of active ingredients. Doesn’t need to be taken with food, just water. Not as many Amazon reviews on the powder but a few claim this made them violently ill.
keep
Long live the nematodes!
Pizza.
Who needs tablets when there’s pizza?
Watched a video on the plaque in the brain, and how there are folks with massive plaque who don’t develop dementia- there must be so eating else going on in dementia patients, either that or there must be so etching going on in the plaque plagued people who don’t develop dementia. Something that protects them from the effects.
Yeah, I was wondering how many tablets constituted the recommended dose. I would always work my way up to a quantity like that and probably split the dose.
It’s always a good idea to read user reviews before purchasing a new supplement. But even that didn’t prepare me for my reaction to ashawaganda, which was of the “violently ill” category. In the case of phytoene, maybe I will go with a micro-dose — say two tablets daily — and hope that over a long period of time it will have a protective effect. Easier for me to do that than consistently eat the fruits and berries that would supply similar.
I think I will just continue to take Natrol JuiceFestiv and VeggieFestiv, superfood products in capsule form that would be expected to contain phytoene based on their constituents. And no chance of GI reactions.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.