Posted on 08/21/2024 9:27:40 PM PDT by ConservativeMind
A study led by investigators found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment—particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70–80% of all breast cancer cases.
In preclinical experiments, researchers found:
—Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer cells by 84% without affecting normal breast cells or causing major side effects.
—Higher concentrations of Manuka honey led to a greater reduction in cancer cell growth.
—Manuka honey reduced levels of signaling pathways that are upregulated in cancer such as AMPK/AKT/mTOR and STAT3, which are involved in tumor cell growth and survival.
—Manuka honey reduced the proliferation of cancer cells but did not affect the growth of normal human mammary epithelial cells, indicating it might target cancer cells specifically.
—Manuka honey induced apoptosis or cell death of breast cancer cells.
—The Manuka honey enhances the effectiveness of existing treatments such as tamoxifen, a commonly used antiestrogen drug in ER-positive breast cancer therapy, when used to together.
Researchers theorize that one of the mechanisms of action of Manuka honey is to block estrogen receptors, making it potentially effective as a nutraceutical against hormone-sensitive breast cancer.
To understand the potential of Manuka honey as a natural treatment for breast cancer, the research team conducted a series of experiments in mice and in ER-positive MCF-7 and triple-negative MDA-MB-231 breast cancer cell lines, which represent two of the most common types of breast cancer. In these models, oral administration of Manuka honey resulted in a significant reduction in tumor growth compared to control groups.
The findings suggest that Manuka honey could potentially be developed into a natural supplement or even a standalone treatment for ER-positive breast cancer.
(Excerpt) Read more at medicalxpress.com ...
There’s a lot more Manuka honey sold every year than is produced. Buyer beware.
Manuka honey is said to work on. Things like diabetic foot and/or ulcers better than traditional methods of treating g the ulcers.
Manuka honey...
The price just doubled and it was already expensive.
Good tip - thanks. Will be cautious.
Manuka is $13 for 8oz at Amazon. Manuka hype is amusing, when I can buy 24oz of verified clover honey for $5 at Aldi last week. It has this seal of verification on the bottle>>>>
https://www.instagram.com/truesourcehoney/
Beware...you really need Raw Manuka with a high UMF (24+ is what I get)...and a high MGO (1122+). I get it thru New Zealand Honey Co. It is not cheap.
Other honey types do not have significant amounts of MGO if any; just sugars and hydrogen peroxide produced by enzymes.
Clover honey has little or no MGO. Also, authentic Manuka such as Med-Honey (for topical use) is priced at more like $7.50 per half ounce.
Any real certified honey will work on a wound/ Though I prefer H2O2. I doubt that Munuka is any better on an open would, than the certified clover I bought last week.
The honey I bought had this certification>>>>>>
“True Source Certified® Honey: This certification ensures that honey is sourced from beekeepers who adhere to strict quality standards. The honey is subjected to comprehensive testing regardless of its origin, providing assurance to consumers about its authenticity and quality.”
The various components significantly help with autolytic debridement, even if the ulcer is not infected.
All honeys will have weak antibacterial action but honeys without MGO do not work as well. Huw could they? Lots of research and traditional supports this.
“Also, authentic Manuka such as Med-Honey (for topical use) is priced at more like $7.50 per half ounce.”
What topical use besides open wounds? You are being scammed by Maunka. Anyways use H2O2 on cuts and wounds. Long term wounds? Use H2O2 many times a day. I bought 32oz H2O2 at Wally Mart three weeks ago for 99¢. Used eyedropper to pour into both ears. H2O2 dissolved all the wax. My hearing improved 7x better
Bee vomit.
I love honey. I have a pantry about 4 x 8 and there’s over a hundred pounds of it in there. All kinds, blueberry, cranberry, orange blossom, buckwheat, wildflower, clover, sunflower, and some others. I’m a honey hoarder. Whenever I have an extra couple bucks and I see a kind of honey I don’t have, I put it in my cart. I use it in my coffee every morning, in marinades, desserts, etc. I’m rarely sick, don’t know if the honey helps with my health or not, but it doesn’t hurt. I’ve tried Manuka, thought it was over priced and was not as flavorful as some of the others. My favorite honey is from my neighbor’s bees. Dark and delicious.
I need to correct that spelling to Medihoney, which is actually a blend of different leptospermum honeys and is considered Manuka (although not with a real high MGO content). The hydrogen peroxide content in honey is an important component for wound care.
“I’ve tried Manuka, thought it was over priced...”
That’s probably true if you’re not specifically using it for medical purposes.
I found this interesting piece of info:
The colour of honey reflects various components present such as polyphenols, minerals, and pollen [21], with dark honey having a higher amount of pigments such as flavonoids [22]. The colour of honey ranges from light yellow, through to amber and dark reddish amber to a nearly black colour [23]. According to the results of Estevinho et al., dark honey has a high level of phenolic compounds and this has been shown to have a good correlation with its higher antibacterial activity [24]. Molan also highlights that dark-coloured honey obtained from the mountains of central Europe has a particularly high antibacterial activity compared to the light variant from the same region [10]. Other dark-coloured honeys have also demonstrated high antibacterial activity such as sweet chestnut honey (Castanea sativa), Manuka honey (Leptospermum scoparium), and Heather honey.
Much more at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589292/
It did.
As a control for another honey product, we used 5% Mesquite honey, a honey native to the southwestern United States and Mexico.
These findings suggest that the pro-apoptotic effects of Manuka honey are not associated with the sugar content of Manuka, nor are the pro-apoptotic effects associated with Mesquite honey from a different region.
Wow!
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