Posted on 08/21/2024 9:27:40 PM PDT by ConservativeMind
A study led by investigators found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment—particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70–80% of all breast cancer cases.
In preclinical experiments, researchers found:
—Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer cells by 84% without affecting normal breast cells or causing major side effects.
—Higher concentrations of Manuka honey led to a greater reduction in cancer cell growth.
—Manuka honey reduced levels of signaling pathways that are upregulated in cancer such as AMPK/AKT/mTOR and STAT3, which are involved in tumor cell growth and survival.
—Manuka honey reduced the proliferation of cancer cells but did not affect the growth of normal human mammary epithelial cells, indicating it might target cancer cells specifically.
—Manuka honey induced apoptosis or cell death of breast cancer cells.
—The Manuka honey enhances the effectiveness of existing treatments such as tamoxifen, a commonly used antiestrogen drug in ER-positive breast cancer therapy, when used to together.
Researchers theorize that one of the mechanisms of action of Manuka honey is to block estrogen receptors, making it potentially effective as a nutraceutical against hormone-sensitive breast cancer.
To understand the potential of Manuka honey as a natural treatment for breast cancer, the research team conducted a series of experiments in mice and in ER-positive MCF-7 and triple-negative MDA-MB-231 breast cancer cell lines, which represent two of the most common types of breast cancer. In these models, oral administration of Manuka honey resulted in a significant reduction in tumor growth compared to control groups.
The findings suggest that Manuka honey could potentially be developed into a natural supplement or even a standalone treatment for ER-positive breast cancer.
(Excerpt) Read more at medicalxpress.com ...
“Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer cells by 84% without affecting normal breast cells or causing major side effects.”
No need to go take a lot, but it surely looks possible some wouldn’t hurt, and might help a fair amount.
Interesting...where do you get it?
Thanks for sharing!
Regards,
The article is reprinted from the "Annals of the Nat'l Association of Manuka Honey Distributors."
Regards,
Costco has it going on sale starting on the 28th. Two 8 ounce jars for $99.
I use small amounts of Manuka every day. Usually buy on Amazon.
No, Manuka is very special. Feel free to educate yourself about methylglyoxal (MGO).
Been used for its extremely potent antibacterial effects for thousands of years. I’m talking about humans; yeah, bees use it too!
Circle back for info on honey
Do you eat it. Or do you apply topically and then lick it off?
What is it about the Manuka tree that does this?
Or is it the way the bees process it?
all honey is antibacterial but manuka is off the charts
it even tastes medicinal compared to other honey
A link to the study...
Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models
A very interesting bit...
...Further, MH treatment stimulated apoptosis of MCF-7 cells in vitro, with most cells exhibiting acute and significant levels of apoptosis that correlated with PARP activation...
Reads to me like the eggheads are on to something...
I am wondering if you do both
A few years back I had a rattlesnake bit cat. After the necrotic tissue fell away, I kept applying manuka honey. Within 48 hours all new tissue was built (out of thin air) and it was a miracle. The hole was so big you could have put a thick cut pork chop in the cavity. The vet had to staple the skin back together (26 staples). She was astonished at the cat’s recovery. And she does not astonish very easily.
Honey: its medicinal property and antibacterial activity
...The antimicrobial activity in most honeys is due to the enzymatic production of hydrogen peroxide. However, another kind of honey, called non-peroxide honey (viz., manuka honey), displays significant antibacterial effects even when the hydrogen peroxide activity is blocked. Its mechanism may be related to the low pH level of honey and its high sugar content (high osmolarity) that is enough to hinder the growth of microbes. The medical grade honeys have potent in vitro bactericidal activity against antibiotic-resistant bacteria causing several life-threatening infections to humans...
Sister K, you might find my reply #16 of interest. :-)
You can buy cough drops that have Manuka honey in them. Pricey but good.
thank you
apparently most cultures around the world know about honey as medicine and wound dressing
we used to here, but got away from it in the 1930s when big pharma was given a platform
Am not interested unless the study also tested using regular honey as a control.
Regards,
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