Knee osteoarthritis injection cuts pain by 58%, regenerates cartilage

New Atlas ^ | JULY 28, 2024 | Paul McClure

[desertsolitaire]

Thanks for asking.
Doing well now.
Was an injury to one knee 20 yrs ago and a lot of torn cartilage removed after.
Joint gradually wore down to bone on bone and replaced it with the Mako model.
Slow recovery and it scarred up before I could regain full bending flexing so had to have it manually broken free again.
Feels great and I don’t think about it much.

[JonPreston]

There’s app 150 articles posted here per day. I’ll let you read them all. You need the help 🤣

[mewzilla]

Would this work if the cartilage in in an area that’s avascular...?

[Red Badger]

Probably.................

[luckystarmom]

I’ll be in that 20 percent in a few years.

I fell and hurt my hip about 14 years ago. Had a hip replacement 2 years ago on my 60th birthday. Now, my other hip has moderate arthritis and starting to be very painful.

The knees are bad too because of all the hip problems. I also have some weird congenital knee problems when my knee cap is small and floats around more than it should.

I find exercising is really helping the knees, but not doing much for my natural hip.

[mewzilla]

Abstract from 2022...

Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials

...For patients with knee OA, intra-articular injection of autologous ASCs or ADSVFs without adjuvant treatment showed remarkable clinical efficacy and safety at short-term follow-up. Some degree of efficacy has been shown for cartilage regeneration in knee OA, although the evidence remains limited. Further RCTs that directly compare ASCs and ADSVFs are needed.

[null and void]

"It’s considered an ‘off-the-shelf’ therapy because it uses donor, or allogeneic, stem cells rather than the patient’s own, the surgical harvesting of which is labor-intensive. Importantly, because the treatment uses mesenchymal stem cells – adult stem cells that can differentiate into other cell types – from adipose tissue or body fat, it doesn’t trigger an immune response."

Oh? Foreign cells aren't rejected?

In what universe?

[Bigg Red]

Sometimes people with joint problems gain weight because they have so much pain that even mild exercise is impossible. You are very compassionate, aren’t you?

[Bigg Red]

Don’t know if this applies to your situation, but I find that avoiding certain foods does wonders for my thumb arthritis.

[fso301]

it uses donor

Does "donor" mean aborted fetus?

[TexasGator]

“There’s app 150 articles posted here per day. I’ll let you read them all. You need the help”

You are counting? Looks like you posted to all. How many other stupid comments instead of doing your own homework?

[ChildOfThe60s]

Does "donor" mean aborted fetus?

"treatment uses mesenchymal stem cells – adult stem cells that can differentiate into other cell types – from adipose tissue or body fat, it doesn’t trigger an immune response."

[NorthMountain]

Does "donor" mean aborted fetus?

A valid question.

See the link in post #7; the answer appears to be "no".

[TexasGator]

I was going to suggest you don’t quit your day job but it appears you don’t have one.

[ConservativeMind]

This will take many years to arrive for use, but this sounds cool.

[nitzy]

I’m glad to hear that.

[fso301]

"treatment uses mesenchymal stem cells – adult stem cells that can differentiate into other cell types – from adipose tissue or body fat, it doesn’t trigger an immune response."

Thanks

[JonPreston]

Who has time to read articles with a Clown 🤡 like you stalking me ✌️

[TexasGator]

“Who has time to read articles with a Clown 🤡 like you stalking me ✌️”

Since when is replying to posts ‘stalking’?

[JonPreston]

Hush 🤡