Posted on 10/16/2023 6:18:16 PM PDT by Libloather
Scientists are calling for stage 3 clinical trials of an Alzheimer's drug to be scrapped after a report highlighted serious doubts about the legitimacy of research that helped the medicine reach that stage.
A long-awaited report by the City University of New York (CUNY) accused one of its faculty members, neuroscientist Hoau-Yan Wang, of egregious misconduct concerning 20 research papers — defined as workplace behavior so outrageous, dangerous, or illegal that an employer cannot reasonably expect to correct it through progressive discipline.
According to the 50-page document obtained by Science, Mr Wang could not provide original data to disprove allegations he had manipulated images in his research papers, many of which provided critical support for the Alzheimer's drug simufilam's jump from the lab into clinical studies.
CUNY biochemist Kevin Gardner told Science the report's findings were 'embarrassing beyond words,' while Vanderbilt University neuroscientist Matthew Schrag said the ongoing trial should 'certainly be shut down.'
The allegations were prompted by initial doubts over the doctored images raised by two scientists in August 2021.
Mr Wang is a long-standing collaborator with biotech company Cassava Sciences, whose work on the experimental Alzheimer's drug simufilam has been heavily criticized.
Simufilam is a drug in tablet form that claims to prevent the buildup of amyloid proteins in the brain that are a hallmark sign of Alzheimer's disease.
Along with Wang, Cassava's senior vice president for neuroscience Lindsay Burns is also being deemed at fault. Burns is a co-author alongside Wang on some of the papers in question.
The CUNY investigative committee found numerous signs images in Wang's research papers were used multiple times, cut and pasted, and altered, 'thereby presenting falsified or fabricated biochemical data.'
One of the papers in question was a 2012 paper published in The Journal of Neuroscience, with both...
(Excerpt) Read more at dailymail.co.uk ...
Any Chinese scholar should have to be their data heavily scrutinized fraud is rampant there culturally and people make up anything and everything to get ahead. This is less applicable to American born Chinese because they aren’t indoctrinated into that culture.
Not saying non Chinese aren’t capable of faking data, just there the odds are higher with the Chinese. When I saw this headline my first thought was “ I bet the person involved is Chinese”.
Chinese
firm bought into MD Andersons Proton Center. no idea if they still own their stake
Wang Bee Wong
Data Bee Krap
Ho Lee MoH Lee
Gadolinium?
I worked for a radiology practice and one of the founding doctors said that it makes tumors in the brain so easy to see.
I am not surprised. Frankly, I feel vindicated.
I’ve been aware of some nasty facts and, of course, rather tin-hat stuff pertaining to AZ research. It was on this basis I classified all AZ fundraising as fraudulent.
I never published that article, but the facts remain and this better start a steamroller against the fraudulent charities operating under ‘ending Alzheimer’s research’.
Researchers have been fudging data for decades. Peoples lives get terribly hurt. The drug companies pay the hurt and their survivors off and keep researching. Prostaglandin inhibitors we’re a hot commodity for pain control as they modulated pain perception.The problem is prostaglandins also dilate blood vessels especial renal arteries along with coronary arteries. The fact people were having heart attacks and going into renal failure was hidden in studies. All of a sudden a lot of prostaglandin inhibitors disappeared from the market with zero announcement.
Yes it does. It also now comes with a warning that you have to sign off on. Most people just sign it without thinking. I did. And it caused me a lot of problems.
Great. The only pain medicine that works on me is in that category....but i only take on a very limited basis..like maybe once a week.
SomeCox 2 are approved.
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