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Next-generation treatment reduces symptoms, preserves sexual function in men with enlarged prostate (Optilume)
Medical Xpress / Wolters Kluwer Health / Journal of Urology ^ | Aug. 10, 2023 | Steven A. Kaplan et al

Posted on 08/14/2023 12:47:30 PM PDT by ConservativeMind

Treatment with the recently approved, minimally invasive Optilume BPH device improves urinary symptoms while preserving sexual function in men with benign prostatic hyperplasia (BPH), concludes a randomized trial.

The Optilume BPH Catheter System offers a new type of minimally invasive treatment, featuring a dual mechanical and pharmacological mechanism of action. In the Optilume procedure, an uncoated balloon catheter is used to open a passage between the lateral lobes of the prostate (anterior commissurotomy).

A second balloon, coated with the antiproliferative drug paclitaxel, is then deployed to further widen the opening. The addition of paclitaxel is thought to prevent continued enlargement of the prostate and prevent re-fusion of the lateral lobes. The Optilume BPH system was approved by the US Food and Drug Administration earlier this year.

100 patients were assigned to undergo active treatment with Optilume. The rest underwent a sham procedure to mimic Optilume treatment.

Men undergoing active Optilume treatment had greater improvement in BPH-related symptoms, as shown by the standard International Prostate Symptom Score (IPSS). From an initial value of about 24 (on a range from 0 to 35), IPSS score decreased by a median of 11.5 points with Optilume versus 8.0 points with sham treatment.

The improvement was maintained through 12 months' follow-up in the Optilume group, but not in the sham group. About three-fourths of patients undergoing Optilume treatment had at least 30% improvement on the IPSS, compared to one-third of the sham group.

The Optilume group also had a dramatic increase in urine flow rate, greater than with previous minimally invasive treatments; and significant improvement in scores for quality of life. Adverse effects were generally mild to moderate. Importantly, sexual function was not adversely affected, including erectile and ejaculatory function.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: prostate
This is available today.
1 posted on 08/14/2023 12:47:30 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 08/14/2023 12:47:58 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
Gentlemen, get your prostates checked annually.

And I mean get BOTH the digital exam and the PSA. I personally know of men, my husband included, who had normal PSAs but the digital exam caught the cancer.

Put aside the annoyance of that 3-second violation of your body and consider that this is about detecting cancer.

3 posted on 08/14/2023 12:55:30 PM PDT by Lizavetta
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To: Lizavetta

Gentlemen, get your prostates checked annually.
And I mean get BOTH the digital exam and the PSA. I personally know of men, my husband included, who had normal PSAs but the digital exam caught the cancer.

Put aside the annoyance of that 3-second violation of your body and consider that this is about detecting cancer.

++++++++++++++++++++++++

A wise friend told me “It’s not MY finger.”


4 posted on 08/14/2023 1:44:46 PM PDT by sonova (Ask me about hate speech!)
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To: ConservativeMind

Found mine at 50 through a base line exam.

I had a experimental HIFU removed the right side of the prostate stage 2........absolute normal levels and no adverse side effects, do it.

6 years Now.


5 posted on 08/14/2023 1:54:56 PM PDT by Kakaze (I'd like the Republic back)
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To: Lazamataz

Finally.....A solution !


6 posted on 08/14/2023 2:08:57 PM PDT by Candor7 (( Ask not for whom THE Trump trolls...He trolls for thee!)<img src=""width=500></img>)
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To: Kakaze

Excellent! You are the only person I’ve heard who has had that specific procedure, but I was wanting that for a relative for a different issue.

How did that go? Was it completely outpatient? Are you saying your PSA was a 50?


7 posted on 08/14/2023 3:29:48 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Ping


8 posted on 08/14/2023 3:48:02 PM PDT by Man from Oz
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To: Lizavetta

I don’t think any doctor I see does the fickle finger of fate exam any more. Not my primary (my old one did), nor my urologist.

Who would perform this procedure?


9 posted on 08/14/2023 6:22:56 PM PDT by John Milner (Marching for Peace is like breathing for food.)
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To: John Milner
The two family practice physicians I have seen in the last 3 years do not do digital exam.

Get a Urologist/ Proctologist. Its their specialty. Mine did the exam on the first visit. Relied on the PSA for the second.

10 posted on 08/14/2023 7:30:45 PM PDT by Pete from Shawnee Mission
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To: ConservativeMind
Thanks!

Good to know!

11 posted on 08/14/2023 7:31:10 PM PDT by Pete from Shawnee Mission
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