Posted on 07/07/2023 4:37:26 PM PDT by ConservativeMind
Recurrent cystitis (RC) is a frequent infection of the urinary tract and bladder, which is highly prevalent among postmenopausal women. Under healthy circumstances, the human vagina is home to a host of beneficial intestinal bacteria, such as Lactobacilli. However, in the case of urinary tract infections (UTIs), there is a decrease in the abundance of Lactobacilli and an increase in pathogenic bacteria, such as Escherichia coli (E. coli).
To bridge this gap, scientists demonstrated the relationship between vaginal microbiota and RC by comparing the vaginal microbiota of postmenopausal women with and without cystitis.
When comparing the vaginal microbiome in the RC and the prevention group, while a few similarities in the diversity of bacterial species, their relative abundance differed between the two groups. The team didn't find any Lactobacilli in the vaginal samples of postmenopausal patients with RC. Instead, the dominant species were various members of the Enterobacteriaceae family, which includes many uropathogenic bacteria. This is in stark contrast to healthy vaginal microbiota, which is rich in healthy intestinal bacteria like Lactobacilli. Notably, the relative abundance of Lactobacilli in the RC-prevention group was much higher (19%) than in the RC group, due to the suppository.
"We found that the vaginal microbiota in postmenopausal women with recurrent cystitis is essentially different," says Mr. Sekito. The study shows that RC occurs when Lactobacilli are depleted and replaced by pathogenic bacteria, like E. coli. Current treatment for RC involves anti-microbial agents, which are prone to antibiotic resistance. This research suggests an alternative therapeutic avenue in the form of vaginal suppositories containing Lactobacilli that can help reduce the imbalance in vaginal microbiota, and in turn reduce RC occurrence.
Further, the frequent use of antimicrobials in cases of recurring infections can even lead to severe forms cystitis, which are even more difficult to treat.
(Excerpt) Read more at medicalxpress.com ...
It would be very frustrating to have an endemic issue with UTIs.
Lactobacillus is present in some fermented foods such as:
Yogurt
Some Cheese
Kefir
Sauerkraut
Kimchi
Olives
Pickles
AWESOME!
I’ve seen this pro-biotic approach already pushed. Long been available. But not very common. Long the idea has been for the obvious yeast problems.
BTW, it IS agonizing.
My saving grace was a wonderful drug called Urogesic. So rare I didn’t even know what its name was for years after my doc finally Rx it. And most doctors and pharmacists have no idea what it is. It was a God-send for 5 years. But I seem to be having more trouble again. But I still swear by it.
They mean a direct insert, not oral. Oral does little for anything outside the gut.
Good news for all birthing persons. It’ll probably make chest feeding easier too.
We need to lead a nationwide protest and boycott until this suppository is available for men
Direct insert into the urethra for cystitis?
Uh, the other.
I shouldn’t even post so much on this embarrassing topic.
I read it as directly inserted in the vagina.
I find interesting the extent to which we live with millions (billions?) of bacteria, in a mutually beneficial relationship.
Are you saying lactobacillus inserted into the vag. works for cystitis, but oral lactobacillus does not? Does that make sense?
I get your point. But unfortunately the 2 are quite too close for comfort. Part of having UTI problems is endless cycles of UTI and vag yeast. It’s agony.
The ur is so close to the vag that inflammation irritates the other part. They’re at least a lot closer than gut.
Ah, but the intestines are all wrapped around there too. The yeast is from taking antibiotics. Yogurt definitely helps to prevent yeast infections when antibiotics wipe out the normal flora.
Are you saying lactobacillus inserted into the vag. works for cystitis, but oral lactobacillus does not? Does that make sense?
Both can work but I think the suppository would work better since the bacteria would have an easier time colonizing the area.
For those saving pennies, make some yogurt.
Plain yogurt with active cultures. Use the same equipment that you would for other vaginal treatments.
I would think greek yogurt being thicker would work better.
I know that it HELPS in many cases. But, it isn’t a cure-all.
Sometimes you read an article on vaginas and you wish there was an unread button.
I read somewhere where children born via C Section often are missing the necessary bacteria needed in their gut that they obtain by being born vaginally.
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