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Opioids no more effective than placebo for acute back and neck pain, finds clinical trial
Medical Xpress / University of Sydney / The Lancet ^ | June 28, 2023 | Christine Lin et al

Posted on 06/29/2023 9:25:39 PM PDT by ConservativeMind

Opioid pain-relieving medicines are not more effective than a placebo in relieving acute back and neck pain and may even cause harm, according to a world-first trial.

Over 577 million people worldwide experience low back and neck pain at any one time.

The OPAL trial recruited close to 350 participants from 157 primary care and emergency department sites. Participants with acute-meaning sudden and generally short-term-back or neck pain were randomly allocated to a six-week course of a commonly prescribed opioid or a placebo.

Both groups also received standard care including advice to avoid bed rest and stay active. Participants were followed for 52 weeks.

Study results:

At six weeks, those who received opioids did not have better pain relief than those given the placebo.

Quality of life and pain outcomes at long-term follow-up were better in the placebo group.

Patients who received opioids were at a small but significantly higher risk of opioid misuse 12-months after their short course of medication.

The research team says that according to current back and neck pain guidelines opioids can be considered as a last resort if all other pharmacological options have failed, however, this study is evidence that opioids should not be recommended at all.

"We have clearly shown there is no benefit to prescribing an opioid for pain management in people with acute back or neck pain, and in fact, it could cause harm in the long-term even with only a short course of treatment," said lead investigator Professor Christine Lin.

"Opioids should not be recommended for acute back and neck pain. Not even when other drug treatments are not able to be prescribed or have not been effective for a patient."

The study complements previous research into opioid use for chronic (long-term) low back pain which found a small treatment benefit.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: fakenews; opioids; pain
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It is frustrating there are not a lot of truly great options for back issues.
1 posted on 06/29/2023 9:25:39 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 06/29/2023 9:26:05 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Now our streets are going to be filled with passed out Placebo Addicts.


3 posted on 06/29/2023 9:28:26 PM PDT by Round Earther
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To: Round Earther

That made me smile.


4 posted on 06/29/2023 9:30:04 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

If people aren’t given opioids for pain, they’ll go find it (fentanyl). And I’m talking about everyday people here. Opioids will simply go totally black market rogue. We’re halfway there now.


5 posted on 06/29/2023 9:31:40 PM PDT by rexthecat
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To: ConservativeMind
This is one of those studies that I would like to know who paid for.
AND what new miracle drug is waiting in the wings ...

Because it is total BS.

Perhaps with the dose level they allow now ... or perhaps the patients were not properly taught how to utilize the meds.

There is no way that the proper use of opiates did not result in a better life quality for real pain patients.

So ...... I call BS.

6 posted on 06/29/2023 9:39:17 PM PDT by 1of10 (be vigilant , be strong, be safe, be 1 of 10 .)
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I call BS


7 posted on 06/29/2023 9:40:11 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: ConservativeMind

Soon you’ll be lucky to get aspirin.


8 posted on 06/29/2023 9:48:50 PM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Vendome

My only lifetime experience with significant pain (other than my first two marriages - could I have a rim shot?) was about 4 months of severe back pain from a poor decision to lift some paving stones in a bad position. I burst a disc at L4/5 and the pain was beyond imagination. I wanted to avoid surgery - so I spent several months hoping it would go away on its own. Then I scheduled the surgery, but it was about 45 days out and the pain was a major problem that obstructed my entire life. The Neurological surgeon prescribed Gabapentin, and that was remarkably effective. I had the surgery just before COVID obstructed all elective surgeries for a while. Solved the problem perfectly. But for the time I was waiting for it - the pain was unreal. Ask your MD about Gabapentin, it seems to have broad application, worked for me. Probably a 98% reduction in pain.


9 posted on 06/29/2023 9:53:04 PM PDT by Wally_Kalbacken
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To: ConservativeMind

The opioid epidemic means they want to massively cut back legitimate use. People in pain will be denied.
“Studies” like this will be used to justify the new policy.

The Lancet lost all credibility during covid.


10 posted on 06/29/2023 9:58:32 PM PDT by DesertRhino (Dogs are called man's best friend. Moslems hate dogs. Add it up..)
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To: DesertRhino

Sounds like the way they solve ‘gun crime’.


11 posted on 06/29/2023 10:08:58 PM PDT by Still Thinking (Freedom is NOT a loophole!)
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To: DesertRhino

But 9ther than the fact that leftards are control freaks as well as sadists, what do they get out of this?


12 posted on 06/29/2023 10:10:57 PM PDT by Still Thinking (Freedom is NOT a loophole!)
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To: Wally_Kalbacken

yep, big no for me on gabapentin - eye issues from it. Also totally ineffective for me during the 10-12 days I was on it until my eyesight was so blurry I thought I was going blind.

The root of the problem needs to be found and dealt with efficaciously (can be extremely difficult and requires one to advocate for themselves, sometimes vociferously). During that time of intense pain, something intense is needed for pain management so one can ambulate and attempt physical therapy if warranted.

Personally, I can only take opioids for a few days, then they make my gut hurt so bad it is worse than taking nothing.


13 posted on 06/29/2023 10:13:28 PM PDT by jurroppi1 (The Left doesn't have ideas, it has cliches. H/T Flick Lives)
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To: Round Earther

LOL


14 posted on 06/29/2023 10:14:35 PM PDT by nutmeg (My 'pride flag' is the AMERICAN FLAG)
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To: ConservativeMind
Dr. Richard Sackler of Purdue Pharma invented the ubiquitous "Pain Assessment Tool" you see in all the hospitals to sell as much of the company's oxycontin as possible.


15 posted on 06/29/2023 10:25:47 PM PDT by E. Pluribus Unum (The worst thing about censorship is ████ █ ██████ ███████ ███ ██████ ██ ████████. FJB.)
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To: ConservativeMind

Horse hockey!


16 posted on 06/29/2023 10:30:30 PM PDT by Flaming Conservative ((Pray without ceasing)Xvg)
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To: Wally_Kalbacken
“Gabapentin”

Is not really a pain med.... it acts on the brain to prevent seizures and relieve pain for certain conditions in the nervous system.
it is an anticonvulsant medicine used for epilepsy ...it can help with anxiety, alcohol withdrawal

So depending on the type of pain... gabapentin can help but
it's also used for treating depression and anxiety,because it calms neurons in the brain.
For muscular skeletal damage it really gives minimal relief.

17 posted on 06/29/2023 10:41:03 PM PDT by 1of10 (be vigilant , be strong, be safe, be 1 of 10 .)
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To: jurroppi1

“my gut hurt so bad it is worse”

This is an example of not being taught to use the meds correctly. I would wonder if your MD is a trained pain specialist.


18 posted on 06/29/2023 10:44:34 PM PDT by 1of10 (be vigilant , be strong, be safe, be 1 of 10 .)
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To: 1of10

Rightly so. No one postulates that an opioid is going to change the six week pain rating for anything acute. They could have run the same study for a broken arm or a heart attack. “Researchers found that the level of chest pain 6 weeks after a heart attack was the same between a placebo group and a morphine group used for acute chest pain. The difference being that the first 48 hours was hell on earth for the placebo group, while the morphine group actually wanted to continue living.”
How moronic. Essentially a straw man study design.
Doctor: wow, That’s a nasty broken arm you have there.
Patient: Doc, can you give me anything for pain?
Doctor: Studies show that in 6 weeks whether I give you pain medicine now or a placebo, you arm is going to feel the about the same, so here, suck on some rocks.


19 posted on 06/29/2023 10:47:35 PM PDT by swingdoc
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To: E. Pluribus Unum

THAT SCALE IS THE STUPIDEST THING EVER CREATED !!!

These jackasses never use Me for any of these “studies” and if they did they would delete My input/answers.

Stupid F&@$KS THAT DON’T KNOW THEIR A$$€$ FROM A HOLE IN THE GROUND !!!


20 posted on 06/29/2023 11:43:24 PM PDT by mabarker1 ( (Congress- the opposite of PROGRESS!!! A fraud, a hypocrite, a liar. I'm a member of Congress!!!)
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