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Did Scientists Accidentally Invent an Anti-addiction Drug?
The Atlantic ^ | MAY 19, 2023 | By Sarah Zhang

Posted on 05/22/2023 8:38:43 AM PDT by Red Badger

People taking Ozempic for weight loss say they have also stopped drinking, smoking, shopping, and even nail biting.

All her life, Victoria Rutledge thought of herself as someone with an addictive personality. Her first addiction was alcohol. After she got sober in her early 30s, she replaced drinking with food and shopping, which she thought about constantly. She would spend $500 on organic groceries, only to have them go bad in her fridge. “I couldn’t stop from going to that extreme,” she told me. When she ran errands at Target, she would impulsively throw extra things—candles, makeup, skin-care products—into her cart.

Earlier this year, she began taking semaglutide, also known as Wegovy, after being prescribed the drug for weight loss. (Colloquially, it is often referred to as Ozempic, though that is technically just the brand name for semaglutide that is marketed for diabetes treatment.) Her food thoughts quieted down. She lost weight. But most surprisingly, she walked out of Target one day and realized her cart contained only the four things she came to buy. “I’ve never done that before,” she said. The desire to shop had slipped away. The desire to drink, extinguished once, did not rush in as a replacement either. For the first time—perhaps the first time in her whole life—all of her cravings and impulses were gone. It was like a switch had flipped in her brain.

As semaglutide has skyrocketed in popularity, patients have been sharing curious effects that go beyond just appetite suppression. They have reported losing interest in a whole range of addictive and compulsive behaviors: drinking, smoking, shopping, biting nails, picking at skin. Not everyone on the drug experiences these positive effects, to be clear, but enough that addiction researchers are paying attention.

(Excerpt) Read more at 12ft.io ...


TOPICS: Food; Health/Medicine; History; Society
KEYWORDS: addiction; drugs; ozempic; sarahzhang; semaglutide; theatlantic; victoriarutledge; wegovy; weightloss
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To: NorthMountain

Viagra also helps prevent dementia and all sorts of organ conditions by increasing blood flow throughout the body.


21 posted on 05/22/2023 10:15:36 AM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem.)
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To: unixfox

We don’t all need it.


22 posted on 05/22/2023 10:25:06 AM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith….)
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To: Red Badger

How was that even allowed?


23 posted on 05/22/2023 10:40:28 AM PDT by TBP (Decent people cannot fathom the amoral cruelty of the Biden regime.)
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To: one guy in new jersey

Bkmk


24 posted on 05/22/2023 10:53:46 AM PDT by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
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To: Tilted Irish Kilt

I wonder if they gave it to Pharmacy Executives it would cause the Execs to do the right thing?


25 posted on 05/22/2023 11:05:24 AM PDT by DannyTN
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To: NorthMountain
"Viagra was developed as a treatment for high blood pressure. Patients taking it for that noticed the “side effect” kept coming up."

As the story goes, when developing the trials that the people taking the drug refused to turn in leftover tablets.

It didn't take doctors long to figure out why they wanted to hang on to them.

26 posted on 05/22/2023 11:53:52 AM PDT by boop (YOU sit in YOUR chair)
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To: Jewbacca

That’s interesting. Preventing dementia would be a very good thing.


27 posted on 05/22/2023 11:55:14 AM PDT by NorthMountain (... the right of the peopIe to keep and bear arms shall not be infringed)
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To: NorthMountain

Yes, all the PDE-5 inhibitors greatly improve the condition of blood vessels throughout the body, including the brain.


28 posted on 05/22/2023 12:20:58 PM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem.)
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To: boop

“It didn’t take doctors long to figure out why they wanted to hang on to them. “

Because it kept them from rolling out of bed at night?


29 posted on 05/22/2023 1:07:47 PM PDT by Polynikes (Nicht geimpft Mensch 2nd Klasse)
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To: Red Badger

People will get addicted to it


30 posted on 05/22/2023 1:12:14 PM PDT by Fledermaus (It's time to get rid of the Three McStooges; Mitch, Kevin and Ronna!)
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To: Tilted Irish Kilt

Unlikely Big Industry will allow for an anti-addiction remedy


31 posted on 05/22/2023 2:37:17 PM PDT by Gene Eric (Don't be a statist!)
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To: Red Badger

Ozempic® is a GLP‑1 analog

https://www.sciencedirect.com/topics/medicine-and-dentistry/glucagon-like-peptide-1

Glucagon Like Peptide 1
GLP1 neurons are in a prime position to rapidly modify ingestive behavior in direct response to transiently altered levels of metabolic cues (e.g., leptin, glucose) or to neural modulators from other brain sites, including POMC neurons in the arcuate nucleus.

From: Williams Textbook of Endocrinology


32 posted on 05/23/2023 1:21:27 AM PDT by tired&retired (Blessings )
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To: tired&retired

This drug works on the arcuate nucleus of the hypothalamus (ARC).

The ARC, located around the third ventricle near the median eminence, is involved in many processes including regulating the release of hormones (eg, GnRH and prolactin) from the anterior pituitary, the LH surge, lactation, appetite and growth hormone release.

What is the function of the arcuate nucleus of the hypothalamus?
The arcuate nucleus (ARC) of the hypothalamus is particularly regarded as a critical platform that integrates circulating signals of hunger and satiety reflecting energy stores and nutrient availability.


33 posted on 05/23/2023 1:33:16 AM PDT by tired&retired (Blessings )
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To: Red Badger
A drug like this could destroy a capitalist economy

And totally end climate change! The Demonrats were always big believers in better living through chemistry, although their preference was church-funded birth control pills, soy, THC, fentanyl, bioweapons lab viruses, experimental vaccines, and if that didn't work, Zyklon B.

34 posted on 05/23/2023 1:42:05 AM PDT by Reeses
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