 "I thought you said 'moth-infested adzuki-beans'!" |
Posted on 04/03/2023 7:27:39 PM PDT by ConservativeMind
A new research paper was published in Aging, titled "Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series."
In this study, researchers reported on a case series of six women who completed a methylation-supportive diet and lifestyle program designed to impact DNA methylation and measures of biological aging.
"The modifiable lifestyle intervention used by participants in this case series was first investigated in a pilot clinical trial in which participants (all men between the ages of 50-72 years) reduced their biological age by an average of 3.23 years as compared to controls [7]. The case series reported on herein was conducted to further the investigation of a modifiable lifestyle intervention that was largely the same in other populations; importantly in women," write the researchers.
The team carried out an intervention consisting of an eight-week program. This program included guidance on diet, sleep, exercise, and relaxation, supplemental probiotics and phytonutrients and nutritional coaching. DNA methylation and biological age analysis (Horvath DNAmAge clock (2013), normalized using the SeSAMe pipeline [a]) was conducted on blood samples at baseline and at the end of the eight-week period.
Five of the six participants exhibited a biological age reduction of between 1.22 and 11.01 years from their baseline biological age. There was a statistically significant (p=.039) difference in the participants' mean biological age before (55.83 years) and after (51.23 years) the 8-week diet and lifestyle intervention, with an average decrease of 4.60 years.
The average chronological age at the start of the program was 57.9 years and all but one participant had a biological age younger than their chronological age at the start of the program, suggesting that biological age changes were unrelated to disease improvement and instead might be attributed to underlying aging mechanisms.
(Excerpt) Read more at medicalxpress.com ...
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Later
Good job! Sounds like the program at Rancho la Puerta in Tecate Mexico, a place I used to go many years ago.
Was this about weight loss?
Because I weigh 114.
in this present world, how long really do we want to live?.....seriously....
Children under four should not try this
Will this make black pilled conservative go back to voting democrat?
Interesting
Thanx for posting
"I thought you said 'moth-infested adzuki-beans'!" |
Thats huge. Do you know how many 30 year old women want to be 29 again? Every single one.
What was your epiphany?
4.6 years. eh?
And just how was that quantified?
“Do you know how many 30 year old women want to be 29 again?”
I dunno, the 31 year old I ended up marrying was far superior to the 29 year old I had been dating.
*buzzer*
Its not about you. Every 30 year old woman would want to be 29 again.
I appreciate the interest, but it’s top secret.
Holding this one back until I self-publish for a number of reasons, including the target it will paint on my back.
I will share this: After I wrote the first draft, I took a long break and did outreach research to validate the book’s concept at the time. On a comprehensive proof reading I realized that it was overwhelmingly Conservative in nature; during writing, I was so immersed that I literally couldn’t see the forest through the trees in that respect.
I believe that many FReepers can navigate this health minefield if they choose to, but I know why most of the rest cannot.
First, we only have 7.3 years left to inhabit Gaia.
Secondly, if you eat right, don’t drink or smoke and get plenty of rest and exercise, you’ll get 8 more years in an old folks home.
Lastly, my water goal is achieved with bourbon.
YMMV FReegards, CM
114 kg?!
Sheesh!
Well, I hope that you are at least 1.9 meters tall!
Regards,
good sex 2 or 3 times a week would have the same effect...
I once dated a hot little 22-year-old, but broke it off after she complained that my volunteer work for the National Association of Retired Persons (I'm the local chairman) was getting in the way of our relationship.
Regards,
It may not work for everyone the way it works for me (your mileage may vary) BUT when I fast by eating only in the morning my energy level and the way I feel jumps up significantly. I mean it's night and day and it starts the first afternoon when you start to think about eating.
Books have been written about the chemical aspects, but, from a purely anecdotal POV, it feels like your body is waking up from a very groggy nap. All of a sudden your mind is wide awake and crystal clear.
Of course the reason your mind is crystal clear is that it is thinking about food, but once your mind and body realize that food isn't forthcoming (because you have made a decision not to feed them), the food concern goes away and you are left with a very clear head and a very awake body.
I am keenly aware of this because I didn't fast yesterday and I feel like crap this morning.
As to the topic of this thread, fasting will definitely add years to your life and those years will be of higher quality.
Those interested in the mechanics behind fasting should research the subject of "autophagy." Here is a snippet from Healthline.com:
What are the benefits of autophagy?The main benefits of autophagy seem to come in the form of anti-aging principles. In fact, Petre says it’s best known as the body’s way of turning the clock back and creating younger cells.
Khorana points out that when our cells are stressed, autophagy is increased in order to protect us, which helps enhance your lifespan.
Additionally, registered dietitian, Scott Keatley, RD, CDN, says that in times of starvation, autophagy keeps the body going by breaking down cellular material and reusing it for necessary processes.
“Of course this takes energy and cannot continue forever, but it gives us more time to find nourishment,” he adds.
At the cellular level, Petre says the benefits of autophagy include:
Autophagy is receiving a lot of attention for the role it may play in preventing or treating cancer, too.
- removing toxic proteins from the cells that are attributed to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease
- recycling residual proteins
- providing energy and building blocks for cells that could still benefit from repair
- on a larger scale, it prompts regeneration and healthy cells
*snip*
Remember that autophagy literally means “self-eating.” So, it makes sense that intermittent fasting and ketogenic diets are known to trigger autophagy.
“Fasting is [the] most effective way to trigger autophagy,” explains Petre.
“Ketosis, a diet high in fat and low in carbs brings the same benefits of fasting without fasting, like a shortcut to induce the same beneficial metabolic changes,” she adds. “By not overwhelming the body with an external load, it gives the body a break to focus on its own health and repair.”
*snip*
“When the body is low on sugar through fasting or ketosis, it brings the positive stress that wakes up the survival repairing mode,” she adds.
One non-diet area that may also play a role in inducing autophagy is exercise. According to one animal study, physical exercise may induce autophagy in organs that are part of metabolic regulation processes.
This can include the muscles, liver, pancreas, and adipose tissue.
If it doesn’t include ice cream, I am not interested.
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