Posted on 04/03/2023 7:27:39 PM PDT by ConservativeMind
A new research paper was published in Aging, titled "Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series."
In this study, researchers reported on a case series of six women who completed a methylation-supportive diet and lifestyle program designed to impact DNA methylation and measures of biological aging.
"The modifiable lifestyle intervention used by participants in this case series was first investigated in a pilot clinical trial in which participants (all men between the ages of 50-72 years) reduced their biological age by an average of 3.23 years as compared to controls [7]. The case series reported on herein was conducted to further the investigation of a modifiable lifestyle intervention that was largely the same in other populations; importantly in women," write the researchers.
The team carried out an intervention consisting of an eight-week program. This program included guidance on diet, sleep, exercise, and relaxation, supplemental probiotics and phytonutrients and nutritional coaching. DNA methylation and biological age analysis (Horvath DNAmAge clock (2013), normalized using the SeSAMe pipeline [a]) was conducted on blood samples at baseline and at the end of the eight-week period.
Five of the six participants exhibited a biological age reduction of between 1.22 and 11.01 years from their baseline biological age. There was a statistically significant (p=.039) difference in the participants' mean biological age before (55.83 years) and after (51.23 years) the 8-week diet and lifestyle intervention, with an average decrease of 4.60 years.
The average chronological age at the start of the program was 57.9 years and all but one participant had a biological age younger than their chronological age at the start of the program, suggesting that biological age changes were unrelated to disease improvement and instead might be attributed to underlying aging mechanisms.
(Excerpt) Read more at medicalxpress.com ...
“Today’s foods” / “Today’s supplements”
2 cups, dark leafy greens 2 cups cruciferous vegetables 3 cups colorful vegetables ¼ cup pumpkin seeds ¼ cup sunflower seeds 2 servings methylation adaptogens 1 to 2 beets Liver or liver supplement (three, 3-ounce servings per week) 1 serving egg (5-10 per week) Probiotics (2 capsules) Greens powder (*2)
“Healthy habits daily recap” / “Water goal”
I exercised for at least 30 minutes I practiced breathing exercises twice I slept at least 7 hours I fasted 12 hours after my meal 8 cups per day
After eight weeks of that, they lost 4.6 years of biological age.
You can do this approach, too.
A separate study approach had been done with men, and they, too, improved.
It’s legit. They successfully made a 30 year old woman pass for a 29 year old
Not too far off from how we eat. First items are easy to add to a smoothie.
What are 2 servings methylation adaptogens??
Thx for posting.
I understand if young women cut out consuming roosters on a daily basis, that will also slow down aging considerably.
LOL...29 + :)
Exactly how do they measure the future? How do they know when someone will die?
Gawd, I hate virtually everything in that list. Yet, I'm 68 dating 46 and 53 YO women. (I do have McD egg sandwich every day).
An “adaptogen” is a plant-based compound that promotes the body's natural balance within a biochemical pathway, bringing the body back into homeostasis. The term “methylation adaptogen” was first coined by Dr. Michael Stone in Oregon and describes any compound that helps to restore methylation balance, both promoting appropriate methylation and inhibiting aberrant methylation.
Examples of methylation adaptogens include curcumin, betanin, anthocyanins, quercetin, rosmarinic acid, lycopene, and sulforaphane. These phytonutrients are found in abundance in a nutrient-dense diet, but additional supplementation may be helpful in some patients.
https://kresserinstitute.com/treating-methylation-supplementing/
Yes, it does. The first title of my book was “50 is the new 30” before I had my epiphany.
And that includes my having accepted that the premise of such ‘programs’ is defective...as was much of my own pre-epiphany approach.
I have no doubt that improving our diet and health habits can add time to our lifespan.
Most of us are too lazy or obstinate to try it - (probably including me, in many ways :-)
No, they can tell from your DNA and other tests how old your body is acting, which is biological age.
This is from Fortune magazine, and it appears to describe the men’s study regimen:
https://fortune.com/well/2023/02/09/what-is-my-biological-age/
If only.
The diet doesn’t work if yours is as limited as mine is. What I wouldn’t give to be able to eat anything on that list.
:(
What is the name for your allergic condition?
“2 cups, dark leafy greens 2 cups cruciferous vegetables 3 cups colorful vegetables ¼ cup pumpkin seeds ¼ cup sunflower seeds 2 servings methylation adaptogens 1 to 2 beets Liver or liver supplement (three, 3-ounce servings per week) 1 serving egg (5-10 per week) Probiotics (2 capsules) Greens powder (*2)”
Honestly, I’d rather have a cheeseburger and look old.
TY!!
The study used the Horvath clock measurement to determine biological age. It is based on the information theory of ageing. As cells divide in the body, they have to preserve epigenetic controls on the genes in the cell so that they only produce the proteins they’re supposed to and not erroneous ones that can cause inflammation and promote cancer cell growth.
When cells are very old and are no longer dividing, they are called senescent. These cells can no longer repair DNA damage and can pump out harmful erroneous proteins in mature animals including humans.
The Horvath clock looks at these control points, called DNA methylation sites, in different tissues to see if their methylation pattern matches that of new cells that have just divided. The better the match between old and new, the younger the tissue is, and the younger the biological age of the person.
But how’d they determine it was a woman??
Bkmk
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.