Posted on 08/20/2022 8:39:32 PM PDT by ConservativeMind
A randomized, double blind human clinical trial reveals that supplementation with GlyNAC—a combination of glycine and N-acetylcysteine—improves many age-associated defects in older humans and powerfully promotes healthy aging. This is relevant because until now, there have been no solutions toward improving many of these age-related declines in people.
The study shows that older humans taking GlyNAC for 16-weeks improved many characteristic defects of aging. This includes oxidative stress, glutathione deficiency and multiple aging hallmarks affecting mitochondrial dysfunction, mitophagy, inflammation, insulin resistance, endothelial dysfunction, genomic damage, stem cell fatigue and cellular senescence. These were associated with improvements in muscle strength, gait speed, exercise capacity, waist circumference and blood pressure.
"This is the first randomized clinical trial of GlyNAC supplementation in older humans, and it found that a wide variety of age-associated abnormalities improved in older adults supplemented with GlyNAC, while no improvements were seen in those receiving placebo," said author Dr. Rajagopal Sekhar.
The improvements in oxidative stress, glutathione levels and mitochondrial function in the muscle tissue of older humans taking GlyNAC were similar to the improvements in organs such as the heart, liver and kidneys of aged mice supplemented with GlyNAC as reported in the researchers' recent publication. Taken together, the results of these studies show that GlyNAC supplementation can improve these defects in many different organs of the body. "GlyNAC supplementation in aging mice increased their length of life mice by 24%," said Sekhar. "Gait speed is reported to be associated with survival in older humans. Our randomized clinical trial found a significant improvement in gait speed in older humans supplemented with GlyNAC. This raises the interesting question of whether GlyNAC supplementation could have implications for survival in people."
(Excerpt) Read more at medicalxpress.com ...
We’ve been taking 600 mg NAC daily. I found that if I take it at night, my dreams become very vivid, and for me sometimes a little weird, so taking it in the morning instead has helped that. I have no idea why I’m wired that way. It doesn’t seem to affect my husband in that regard.
I’d like to give this combination of glycine and NAC a try.
BTTT for GlyNAC .
Amazon now carries nac - too much $ to be be made by an excellent supplement
https://simplynutrients.com/nac-glycine-powder/?sku=PE-NGY1&gclid=EAIaIQobChMIlpiv1qPY-QIVismUCR3bawA4EAQYASABEgKhb_D_BwE Found a formula that has both in it
You either hit the ball a LONG ways off the first tee or take your time getting out of bed.
Thorne rocks.
Got it. Both definitions have their uses.
I can say that you can use the NOW Glycine one pound powder form with Swanson capsule NAC form for under $0.50/day for 1,800 mg of Glycine and 1,800 mg of NAC. That Pure Encapsulation version is nearly triple that cost per scoop of 3,600 mg combined Glycine and NAC, but still quite a bit cheaper than the Nestle Celltrient Cellular Protect form.
The secret to cheap NAC from Swanson is when they include their branded NAC on a 35% or 40% sale occasion, which you only find by checking your emails and visiting the Swanson NAC web page.
Ive been taking NAC for the last 3 1/2 years, and have been reading studies on Glycine the last little while, and added it to my Supps about three months ago.
remember people; when taking NAC, to make sure your vitC is at least equal or more than the amount of NAC you’re taking.
Vitamin C does help extend the body’s use of the glutathione the GlyNAC helps produce, but I have not heard of any ratio of Vitamin C to either amino acid in GlyNAC.
I do recall “sufficient” Vitamin C can extend the glutathione by over 50%, though.
Marking
Thank you FRiend,
Tatt
To be able to view this study, it costs $52, and you only get access for 24 hours.
Crazy!
bump
Hmmmmmmmm, Amazon now sells NAC (it came off the shelves in the last year+ as the FDA said it might need a patent) and Quercetin too. Covid over?
Good to know. I see NAC in stores - I’m not sure how the Fed’s plan to ban it is going.
This is a nice writeup of several GlyNAC studies:
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