Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Research links red meat intake, gut microbiome, and cardiovascular disease in older adults
Medical Xpress / Tufts Univ. /JAMA Network Open / Arteriosclerosis Thrombosis and Vascular Biology ^ | August 1, 2022 | Amanda M. Fretts et al

Posted on 08/02/2022 9:17:25 PM PDT by ConservativeMind

Does eating more red and processed meat raise the risk of cardiovascular disease? Despite intense study, the impact of animal source foods on atherosclerotic cardiovascular disease (ASCVD) is vigorously debated, and effects remain unclear.

A study quantifies the risk of ASCVD associated with meat intake and identifies underlying biologic pathways that may help explain this risk. The study shows higher meat consumption is linked to higher risk of ASCVD—22 percent higher risk for about every 1.1 serving per day—and that about 10 percent of this elevated risk is explained by increased levels of three metabolites produced by gut bacteria from nutrients abundant in meat. Higher risk and interlinkages with gut bacterial metabolites were found for red meat but not poultry, eggs, or fish.

Several blood biomarkers were measured, including levels of the gut-microbiome generated trimethylamine N-oxide (TMAO) and two of its key intermediates, gamma-butyrobetaine and crotonobetaine, derived from L-carnitine, abundant in red meat.

"Interestingly, we identified three major pathways that help explain the links between red and processed meat and cardiovascular disease—microbiome-related metabolites like TMAO, blood glucose levels, and general inflammation—and each of these appeared more important than pathways related to blood cholesterol or blood pressure," said author, Dariush Mozaffarian. "This suggests that, when choosing animal-source foods, it's less important to focus on differences in total fat, saturated fat, or cholesterol, and more important to better understand the health effects of other components in these foods, like L-carnitine and heme iron."

In May, researchers reported that TMAO and related metabolites in older adults are positively associated with a higher risk of death whether deaths were related to cardiovascular disease or another disease. Participants with the highest levels of plasma TMAO and its biomarkers had a 20 to 30 percent higher risk of death compared with those having the lowest levels.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cardiac; gitract; heart; meat
Navigation: use the links below to view more comments.
first previous 1-2021-31 last
To: 867V309

When bacon was deemed bad did it for me


21 posted on 08/03/2022 12:09:11 AM PDT by Nifster (I see puppy dogs in the clouds )
[ Post Reply | Private Reply | To 4 | View Replies]

To: dennisw

I’m not going to let a salad sit for eight hours at room temp


22 posted on 08/03/2022 12:14:10 AM PDT by Nifster (I see puppy dogs in the clouds )
[ Post Reply | Private Reply | To 16 | View Replies]

To: cherry

Bacon... you left out bacon! /s


23 posted on 08/03/2022 12:14:25 AM PDT by mad_as_he$$
[ Post Reply | Private Reply | To 18 | View Replies]

To: ConservativeMind

This is a split hoofed animal that chews the cud. It’s good for food. The problem with it is in the finishing. They are finished (fed) foods to make fat and increase weight.

The study is flawed.

What makes colesterol problems is starches. Eliminate starches and the body changes its chemistry to use the over abundant fats as energy.

Also, if vitamin C is too low, the body will utilize calcium for blood vessel repair. Viola..atherosclerosis is born.

Funny how we don’t see many studies on the effects of junk food.

There is an agenda here with red meat.


24 posted on 08/03/2022 12:33:17 AM PDT by PrairieLady2
[ Post Reply | Private Reply | To 1 | View Replies]

To: Nifster

Pickle is the same and you did not die. You can eat the pro biotic powder straight like most. Or eat the salad right away.


25 posted on 08/03/2022 3:47:28 AM PDT by dennisw
[ Post Reply | Private Reply | To 22 | View Replies]

To: moonhawk

“I would think they would attempt to distinguish red meat from processed meat. Not the same thing.”

Why should they? Since, if they do that, they won’t get the results they need for continued funding.


26 posted on 08/03/2022 4:29:04 AM PDT by BobL (The Globalists/Neocons desperately want Ukraine to win...makes it easy for me to choose a side)
[ Post Reply | Private Reply | To 8 | View Replies]

To: 867V309
I quit listening to dietary “research” when the government said eggs and butter were bad but margarine (trans-fats) were good.

The statement above is very good advice.

I tend to eat more fish and chicken and a lot of veggies.

27 posted on 08/03/2022 5:04:10 AM PDT by TheConservativeTejano (The Business of America is Business)
[ Post Reply | Private Reply | To 4 | View Replies]

To: PrairieLady2
What makes colesterol problems is starches. Eliminate starches and the body changes its chemistry to use the over abundant fats as energy. Also, if vitamin C is too low, the body will utilize calcium for blood vessel repair. Viola..atherosclerosis is born. Funny how we don’t see many studies on the effects of junk food. There is an agenda here with red meat.

Very good advice and we need to lose weight so red meat and breads will make you gain weight as well.

28 posted on 08/03/2022 5:08:41 AM PDT by TheConservativeTejano (The Business of America is Business)
[ Post Reply | Private Reply | To 24 | View Replies]

To: ConservativeMind

You can’t believe anything they say anymore.


29 posted on 08/03/2022 5:53:11 AM PDT by Freedom_Is_Not_Free (America -- July 4, 1776 to November 3, 2020 -- R.I.P.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

bookmark


30 posted on 08/03/2022 6:52:10 AM PDT by Cats1
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

To paraphrase George Carlin,* “Steak is worth cancer.”

If grim death himself were serving me my chatueabriand, my response would be to ask, “Please pass the Bearnaise sauce.”

* Carlin originally said it of bacon, but both are equally true.


31 posted on 08/03/2022 10:09:14 AM PDT by Paal Gulli
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-31 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson