Posted on 07/04/2022 2:44:50 PM PDT by ConservativeMind
Prostate-specific antigen (PSA) is a serine protease and one of the most abundant proteins secreted by the human prostate epithelium. PSA is used as a well-established marker of prostate cancer. The involvement of PSA in several early events leading to the development of malignant prostate tumors has made it a target for prevention and intervention. It is thought that PSA cleaves insulin-like growth factor binding protein-3 (IGFBP-3), providing increased local levels of IGF-1, leading to tumor growth. Separately, there are data that suggest an enzymatic regulatory role for dietary boron, which is a serine protease inhibitor. In this study we have addressed the use of boric acid as a PSA inhibitor in an animal study. We proposed that dietary supplementation with boric acid would inhibit PSA and reduce the development and proliferation of prostate carcinomas in an animal model. We tested this hypothesis using nude mice implanted subcutaneously with LNCaP cells in Matrigel. Two groups (10 animals/group) were dosed with boric acid solutions (1.7, 9.0 mgB/kg/day) by gavage. Control group received only water. Tumor sizes were measured weekly for 8 weeks. Serum PSA and IGF-1 levels were determined at terminal sacrifice. The size of tumors was decreased in mice exposed to the low and high dose of boric acid by 38% and 25%, respectively. Serum PSA levels decreased by 88.6% and 86.4%, respectively, as compared to the control group. There were morphological differences between the tumors in control and boron-dosed animals, including a significantly lower incidence of mitotic figures in the boron-supplemented groups. Circulating IGF-1 levels were not different among groups, though expression of IGF-1 in the tumors was markedly reduced by boron treatment, which we have shown by immunohistochemistry. These data indicate that low-level dietary boron supplementation reduced tumor size and content of a tumor trophic factor, IGF-1.
(Excerpt) Read more at journals.sagepub.com ...
SpaceJunkie2001, you never once said you took that amount. Also, you literally told others to take an admitted 110+ mg daily amount, which blows past medically safe levels I already researched and provided. Instead, suggest alternatives and let people come to such conclusions for themselves.
We don’t need to get sued for something construable as “medical advice.”
“¼ teaspoon (940 mg ~ 1,000 mg) of borax in 1 liter of water for men and 1/8 teaspoon (470 mg ~ 500 mg) of borax in 1 liter of water for women each day.”
What part of the above don’t you get? You are bordering on delusional. You are a prideful person that CANNOT admit error and that is not a good place to be. God said humble yourself or He’ll do it for you.
PSA is used as a well-established marker of prostate cancer.
~~~~~~~~~~~~~~~~~
That might be the case but if Dr. Stamey was alive, he’d disagree with PSA testing being used that way....
You might consider limiting the amount of sugar in your diet, if you aren’t doing that already.
https://www.pcf.org/c/prostate-cancers-sweet-tooth/
TTIUWPONM!
;-)
If you wouldn’t mind - please tell us how you pick up these posts for us - I believe I’m on the everything list - but do you roll through a list of medical publications?
I’m pretty much healthy despite a lifetime of abusing my body but I have friends and family with problems so I very much appreciate hearing the latest. Good job!
Anything on laser-printed livers or lungs would be great.
;-)
For others, I go through various sites, but I get most of my latest study information from Medical Xpress, but it also has a search option to scour through prior postings for a key word(s) you give it. The nice thing is that most study write ups have the PubMed link at the bottom and 90+% of the actual research studies the write ups were pulled from are now free to read.
Do note I only post studies that point to an immediate way to likely address something. There are many more that talk about something in the future or a current practice or issue that someone wanted to highlight, but wasn't “new.”
What sort of liver and lung issues have you noted?
Appreciate your comprehensive posts but keep your eye out for laser-printed lungs.
I'm probably pre-COPD but I'm not complaining - just so you know after 50+ years of smoking I'm surprised to be here at at all at 67. ;-)
Thanks.
Charlie
Useful, current, possibly life-saving information? Good hobby choice.
Thanks for your hard work. ;-)
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