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Grape seed extract found to extend lifespan of old mice
Medical XPress / Nature Metabolism ^ | Dec l. 9, 2021 | Bob Yirka / Qixia Xu et al

Posted on 12/07/2021 6:20:27 PM PST by ConservativeMind

A team of researchers has found that injecting procyanidin C1 (PCC1), a chemical found in grape seed extract, into older mice extended their lifespan. In their paper, the group describes the link between PCC1 and extended lifespan in mice and the experiments they carried out with the material.

Scientists have been trying for many years to understand the aging process. The hope is that once it is understood, mitigation efforts can slow or stop the process to allow people to live longer. The researchers screened plant extracts looking for anti-aging capabilities. They came across PCC1. Initial tests showed it reduced the number of senescent cells in the human prostate. Such cells are known to contribute to aging. Intrigued with their results, the researchers tested it further. They found that at low doses it prevented senescent cells from contributing to inflammation, and at higher doses killed them outright without harming other cells.

The team then injected 171 mice with PCC1, 91 of whom were considered to be old. They found that this increased the overall lifespan of the mice by 9 percent and their remaining lifespans by 60 percent, on average. The researchers also injected younger mice with the extract chemical over a period of four months and found it improved their physical fitness. They then injected mice that had cancerous tumors with the chemical and found that doing so helped to shrink tumors when given in conjunction with chemotherapy. They also found it did the same with human tumor cells implanted into mice.

The researchers note that in all of their testing, they found no damage to normal cells, which suggests that PCC1 could be a promising therapeutic treatment for a wide variety of conditions and could very well reduce some of the negative impacts of aging.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: grapeseedextract; mice; pcc1; procyanidinc1
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To: Taxman

No, no seeds! You need to switch to Grappa!


21 posted on 12/07/2021 7:26:48 PM PST by Pete from Shawnee Mission ( )
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To: Mark

Interesting.

I’ma try it now.


22 posted on 12/07/2021 7:40:39 PM PST by AAABEST (NY/DC/LA media/political/military industrial complex DELENDA EST)
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To: ConservativeMind

That’s all we need... more mice and rats.


23 posted on 12/07/2021 7:56:45 PM PST by aquila48 (Do not let them make you "care" ! Guilting you is how they control you. )
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To: ConservativeMind

If you pack em in salt or olive oil, you can extend their shelflife almost indefinitely.

Oh sorry, you meant that other lifespan.


24 posted on 12/07/2021 8:01:51 PM PST by Macoozie (Handcuffs and Orange Jumpsuits)
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To: Covenantor
Y'know, just in case you've got some old mice you've been worried about. :^)

25 posted on 12/07/2021 8:19:28 PM PST by SunkenCiv (Imagine an imaginary menagerie manager imagining managing an imaginary menagerie.)
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To: Skywise

I used to take a big spoonful of milky grape-nuts and suck all the milk out of it and take this hardened structured ball out of my mouth and throw it at my sister’s head when she wasn’t looking.

One time in mid-flight my dad walked in the dining room and witnessed the fling, the ding, and fragmentation. We had us a little talk.

At the next family reunion the next summer, I kept getting these little thumbs ups, winks, and nods from the other uncles and a few older cousins. Huge families have gigantic family reunions.


26 posted on 12/07/2021 9:42:11 PM PST by Clutch Martin (The trouble ain't that there is too many fools, but that the lightning ain't distributed right.)
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To: AAABEST

It should be 100mg per 100 lb weight, but take even more when starting.


27 posted on 12/07/2021 10:17:10 PM PST by Mark (Celebrities... is there anything they do not know? Homer Simpson)
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To: Mark

They (Costco) now have a product called Trunature Resveratrol Plus, with some grapeseed extract in it. I’m taking that now.


28 posted on 12/07/2021 10:41:06 PM PST by matthew fuller (Resist this coercion like it’s slavery. It is. Kevin Homer, MD)
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To: matthew fuller

I’ve been taking Resveratrol for at least 12 years due to its immune system enhancing qualities. It works. I told a guy about it who got sick really easy all the time. He tried and couldn’t thank me enough. He stopped getting sick constantly within weeks.

It does seem to work better on some people than others. It probably helps those who have a somewhat compromised immune system best or it’s just more quantifiable in them.

Resveratrol is the active ingredient in red wine and grape seeds that helps the immune system.


29 posted on 12/07/2021 11:39:33 PM PST by Boomer (Leftism is a mental illness wrapped in a perverse ideology resulting in insanity. FJB)
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To: SunkenCiv

The only reference to dormice I ever came across was in Lewis Carroll’s “Through the Looking Glass”, the Mad Hatter’s Tea Party...and of course Grace Slick’s “White Rabbit”.

“Remember what the dormouse said...”

So I decided to find out about these critters...turned out to be interesting.
;>)


30 posted on 12/08/2021 6:02:56 AM PST by Covenantor (We are ruled...by liars who refuse them news, and fools who can not govern. " Chesterton)
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To: ConservativeMind

Longer living mice.


31 posted on 12/08/2021 6:14:07 AM PST by Repealthe17thAmendment
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To: ConservativeMind

Xlear Nasal Spray contains Grape Seed Extract, wonder if that helps.


32 posted on 12/08/2021 6:25:11 AM PST by chuck allen
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To: Pete from Shawnee Mission

LOL!


33 posted on 12/08/2021 6:28:53 AM PST by Taxman (SAVE AMERICA!)
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To: chuck allen

I thought it had grapefruit seed extract.


34 posted on 12/08/2021 6:43:33 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
That is for opossums.
35 posted on 12/08/2021 6:44:37 AM PST by sport
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To: ConservativeMind

As a side note, Grape Nuts are not made from grape seeds.....


36 posted on 12/08/2021 7:10:54 AM PST by Hot Tabasco (My favorite word is Tweezer)
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To: dfwgator

Yep it isn’t like they have to work hard like humans do.


37 posted on 12/08/2021 7:30:14 AM PST by Vaduz (women and children to be impacIQ of chimpsted the most.)
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To: ConservativeMind

What kind of extended life? Sitting around? Doing self things? That’s not living. Soon as my kids take my car keys, I’m ready for heaven.


38 posted on 12/08/2021 8:07:16 AM PST by lurk ( )
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