Posted on 12/07/2021 6:20:27 PM PST by ConservativeMind
A team of researchers has found that injecting procyanidin C1 (PCC1), a chemical found in grape seed extract, into older mice extended their lifespan. In their paper, the group describes the link between PCC1 and extended lifespan in mice and the experiments they carried out with the material.
Scientists have been trying for many years to understand the aging process. The hope is that once it is understood, mitigation efforts can slow or stop the process to allow people to live longer. The researchers screened plant extracts looking for anti-aging capabilities. They came across PCC1. Initial tests showed it reduced the number of senescent cells in the human prostate. Such cells are known to contribute to aging. Intrigued with their results, the researchers tested it further. They found that at low doses it prevented senescent cells from contributing to inflammation, and at higher doses killed them outright without harming other cells.
The team then injected 171 mice with PCC1, 91 of whom were considered to be old. They found that this increased the overall lifespan of the mice by 9 percent and their remaining lifespans by 60 percent, on average. The researchers also injected younger mice with the extract chemical over a period of four months and found it improved their physical fitness. They then injected mice that had cancerous tumors with the chemical and found that doing so helped to shrink tumors when given in conjunction with chemotherapy. They also found it did the same with human tumor cells implanted into mice.
The researchers note that in all of their testing, they found no damage to normal cells, which suggests that PCC1 could be a promising therapeutic treatment for a wide variety of conditions and could very well reduce some of the negative impacts of aging.
(Excerpt) Read more at medicalxpress.com ...
I took a similar amount another time, just four years ago.
I believe it is worth taking at least a standard daily supplement, of which ours is 400 mg.
Great news for old mice.
So you’re saying the Grape Nuts ads were right?!
Nope, I’ve seen “The Green Mile”
Just hearing that phrase “Old Mice” is amusing.
A black velvet painting with different kinds of rodents smokin’ drinkin’ and playing poker.
“Tastes like wild hickory nuts!”
C.M. I have this, but my understanding was that it was for things like GI Tract problems and diarrhea. I will take another look at it!1
Does it affect drug clearance in the liver like grapefruit? (They warn people taking some medications to avoid grapefruit.)
Wonder if it conflict with Eliquis blood thinner?
According to the NIH, it is known to possibly interfere with anticoagulants.
https://www.nccih.nih.gov/health/grape-seed-extract
See post #12.
It appears possible, but not certain, according to the NIH.
I’ve been taking it for around 40 years. No flu bug got me and no meaningful cold all of that time. Just found out that Costco is no longer selling it.
Does the Sweet Red Wine I drink count?
Why would anyone want that?
Read much about nutrition and discover two of the wonder foods are olives and grapes.
Two items Jesus had.
Want what, specifically?
Thanks! Well, I have been taking Nattozine as a blood thinner, so I need to think about it before starting to use it again. I have also been using Grapeseed oil for cooking!
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