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Ubiquitous food additive alters human microbiota and intestinal environment (Carboxymethylcellulose)
Medical XPress / Georgia State University / Gastroenterology ^ | Nov. 30, 2021 | Benoit Chassaing et al

Posted on 12/02/2021 3:36:41 PM PST by ConservativeMind

New research indicates a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

Carboxymethylcellulose (CMC) is a synthetic member of a widely used class of food additives, termed emulsifiers, which are added to many processed foods to enhance texture and promote shelf life. It had long been assumed that CMC was safe to ingest because it is eliminated in the feces without being absorbed. Experiments in mice found that CMC, and some other emulsifiers, altered gut bacteria resulting in more severe disease in a range of chronic inflammatory conditions, including colitis, metabolic syndrome and colon cancer. However, the extent to which such results are applicable to humans had not been previously investigated.

The team performed a randomized controlled-feeding study in healthy volunteers. Because the diseases CMC promotes in mice take years to arise in humans, the researchers focused here on intestinal bacteria and metabolites. They found that CMC consumption changed the make-up of bacteria populating the colon, reducing select species. Furthermore, fecal samples from CMC-treated participants displayed a stark depletion of beneficial metabolites that are thought to normally maintain a healthy colon.

Lastly, the researchers performed colonoscopies on subjects at the beginning and end of the study and noticed that a subset of subjects consuming CMC displayed gut bacteria encroaching into the mucus, which has previously been observed to be a feature of inflammatory bowel diseases and type 2 diabetes. Collectively the results support the conclusions of animal studies that long-term consumption of this additive might promote chronic inflammatory diseases. Therefore, further studies of this additive are warranted.

"It certainly disproves the 'it just passes through' argument used to justify the lack of clinical study on additives," said Dr. Andrew Gewirtz.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: carboxymethyl; cellulose; cmc; gutbacteria; gutmicrobes; iylm; v8
The only use that appears to be a problem is when it is ingested. This is used for eye drops and in many other items.

If you know someone who has a bowel disorder, this would be worth limiting.

1 posted on 12/02/2021 3:36:41 PM PST by ConservativeMind
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To: ConservativeMind

A lot of companies don’t really care what they sell you.


2 posted on 12/02/2021 3:40:41 PM PST by nickcarraway
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To: ConservativeMind

“CMC is used in baking for its thickening and stabilizing properties. CMC is a food grade water-soluble gum used for its thickening and stabilizing properties.”


3 posted on 12/02/2021 3:44:13 PM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: ConservativeMind
Frozen dough: As a 0.5% replacement for wheat flour and with a D.S. ...

Tortillas: CMC is added to tortillas for shelf life extension and to maintain a pliable texture.

Gluten free bread and cakes: Improves the internal structure like gluten proteins and helps with moisture retention and mouthfeel.

4 posted on 12/02/2021 3:49:18 PM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: ConservativeMind

We can’t rely on the experts


5 posted on 12/02/2021 3:55:25 PM PST by vigilante2
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To: nickcarraway
"...A lot of companies don’t really care what they sell you..."

Yep.
Diabetics, like myself, have a pretty tough time of it.

One of my pet peeves is Malitol/Maltitol - an artificial(?)
sweetener used to replace sugar. It's supposed to be safe
for diabetics to eat - problem is that it is only a few points
lower on the glycemic index scale than is white table sugar
made from sugar cane.

So it's maybe 1/2 of a percent 'healthier' for diabetics than sugar.
And therefore, by law, manufacturers can - and do - put
'SUGAR FREE' and 'SAFE FOR DIABETICS' on the labels
of their manufactured food products.

So you've got to educate yourself as a food chemist, and then
stand around in the supermarket reading food ingredient labels.
I find it rather annoying.

But hey - 'Let The Buyer Beware!'.

6 posted on 12/02/2021 6:32:06 PM PST by GaltAdonis
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To: GaltAdonis
I am not sure any sweetener is really safe not to trigger an insulin response. I've read even a noncaloric sweetener will trigger an insulin response, because they hit the sweet tasting receptors in your mouth.

Maybe, for sweetness you could use cinnamon, or a little vanilla extract.

7 posted on 12/02/2021 6:39:33 PM PST by nickcarraway
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To: ConservativeMind

Pretty much it is wallpaper paste. also useful as lubricant in veterinary medicine to rectally palpate cows and mares. Yes, we wear plastic arm sleeves.


8 posted on 12/02/2021 7:49:57 PM PST by drSteve78 (Je suis Deplorable. STILL)
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To: GaltAdonis
One of my pet peeves is Malitol/Maltitol - an artificial(?) sweetener used to replace sugar. It's supposed to be safe for diabetics to eat - problem is that it is only a few points lower on the glycemic index scale than is white table sugar made from sugar cane.

AND it causes massive stomach upset and diarrhea in a not insignificant number of people who eat it.

9 posted on 12/02/2021 8:01:00 PM PST by Mr. Jeeves ([CTRL]-[GALT]-[DELETE])
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To: GaltAdonis

My wife and I stay away from “Malitol/Maltitol.”

That stuff blows everything out the end of your colon, if you eat too much.

In my wife’s case, it was very tasty “sugar-free” ice cream.

It takes a day to recover.


10 posted on 12/02/2021 8:59:08 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Sounds like the Google reviews for sugar-free Haribos gummies.


11 posted on 12/02/2021 9:04:15 PM PST by Rebelbase ( State Dept. Havana Syndrome victims: Guinea pigs of 5G/graphene oxide vax experiments?)
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To: Mr. Jeeves; ConservativeMind
"...I stay away from “Malitol/Maltitol...”

"...That stuff blows everything out the end of your colon..."

"...it causes massive stomach upset and diarrhea..."

The sweetener Sorbitol also does those things -
with the added 'benefit' that it drastically lowers the
levels of potassium in your bloodstream.

So since I was eating sorbitol-containing breath mints
every day for years, when my endocrinologist
(diabetes doctor) saw that my potassium was alarmingly
low in my blood work, he put me on huge horse-pill sized
tablets of it.

I can barely swallow the huge damned things.
(And yes, I quit those mints.)

But hey, potassium is just needed to keep the heart beating
in proper rhythm - so it can't be all that important, right?

I should become a professional nutritionist,
instead of merely an amateur one - really.

12 posted on 12/03/2021 3:45:00 AM PST by GaltAdonis
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To: GaltAdonis

Low sodium V8 has 850 mg of potassium per 45 calorie serving.

We enjoy drinking it.


13 posted on 12/03/2021 5:35:02 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: GaltAdonis

Look into erythritol and allulose.

We primarily use erythritol, erythritol with monk fruit, and just occasionally allulose.


14 posted on 12/03/2021 5:40:59 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
Erythritol still leads to gas and stomach upset.

I prefer cane sugar, in moderation. :)

15 posted on 12/03/2021 5:55:13 AM PST by Mr. Jeeves ([CTRL]-[GALT]-[DELETE])
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To: ConservativeMind

kombucha........ soles many bowel problems


16 posted on 12/03/2021 6:00:55 AM PST by bert ( (KE. NP. N.C. +12) Free Republic has gone to hell is a Covid handbasket)
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To: ConservativeMind
"Low sodium V8..."

Yep. Thanks!
I've got a bottle of it in the fridge.
Yummy stuff.

17 posted on 12/04/2021 6:00:24 AM PST by GaltAdonis
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To: ConservativeMind
"...We primarily use erythritol, erythritol with monk fruit, and just occasionally allulose."

I use erythritol, sucralose (Splenda), and occasionally
if I'm baking something yummy, unsweetened applesauce
and/or a dab of unsulfured molasses.

Haven't tried Monk fruit or allulose yet, though.

.

I just looked up Allulose - glycemic index of Zero - good.
I'll try it out. The Monk fruit also.
Thanks.

18 posted on 12/04/2021 6:13:26 AM PST by GaltAdonis
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