Posted on 10/19/2021 1:36:11 PM PDT by ConservativeMind
A large proportion of the damaging chemical changes which occur in the body's cells due to diabetes and obesity could be prevented by a naturally occurring molecule, a new study suggests.
In type 2 diabetes, when glucose stays in the blood it is not used as fuel for energy and can instead lead to toxic molecules forming.
Scientists at Nottingham Trent University investigated how this "metabolic stress," resulting from prolonged exposure to high levels of glucose and fat, damages proteins in the blood and cells and prevents them from working properly.
The researchers, writing in the journal Free Radical Biology and Medicine, also studied the effect of "carnosine," a molecule found in human skeletal tissue and consumed in the diet through meat and fish. It can also be taken as a nutritional supplement.
By comparing with the blood of healthy individuals, the team was able to identify disease-associated changes in patients with obesity, type 2 diabetes and gestational diabetes.
Further laboratory work then investigated the extent to which carnosine was able to prevent similar damaging protein modifications in cells and tissues linked to the control of glucose.
The researchers found that carnosine prevented 65–90% of these damaging chemical changes and protected the functional properties of affected cells.
The researchers say that despite the cells being compromised, carnosine was able to preserve cellular function by soaking up the toxic molecules.
"We found that carnosine is able to protect cells that are responsible for controlling blood sugar levels. This increases sensitivity to glucose and also results in greater insulin release.
"While further studies are required, this work has confirmed our hypothesis that carnosine could offer significant therapeutic potential against type 2 diabetes."
(Excerpt) Read more at medicalxpress.com ...
I still wonder if people get type 2 diabetes because they are fat, or get fat because they have type 2 diabetes.
Excess iron causes diabetes.
“Excess iron causes diabetes”
I don’t think I ever had iron overload.
There are other causes. Excess of omega 6 fats causes diabetes.
I think men who consume chocolate or meat consume more iron than they need. Removing unnecessary iron increases ability to process sugar. See this:
Blood Letting in High-Ferritin Type 2 Diabetes
Effects on Insulin Sensitivity and β-Cell Function
https://diabetes.diabetesjournals.org/content/51/4/1000.long
I donate blood every two years to prevent excess iron.
If a person’s blood ferritin is less than 70 ng/ml, the person has an iron deficiency.
“I think men who consume chocolate or meat consume more iron than they need.”
When I was young, I thought the three major food groups were chocolate, meat, and wine.
Good choices.
what dosage were you taking before (and after) doubling?
ah here it was, disregard, thanks
The four food groups that I am aware of are sugar, salt, grease and caffeine. Chocolate has all four, thus it is a super food.
Diabetes is no respecter of persons. Fat people may be more susceptible to diabetes but people with normal weight and even low weight can also suffer with diabetes.
I still wonder if people get type 2 diabetes because they are fat, or get fat because they have type 2 diabetes.
I think the answer is yes.
I got type 2 at 5ft 7, 150 lbs.
More bad genes than anything else I think.
I’m not rigorous enough to use the Dr. Fung protocol so I’m on meds.
bttt
“The four food groups that I am aware of are sugar, salt, grease and caffeine. Chocolate has all four, thus it is a super food.”
Sometimes it even has alcohol in it.
We used to inject cognac into strawberries, then dip them in melted chocolate.
Decadence a la mode.
“Diabetes is no respecter of persons. Fat people may be more susceptible to diabetes but people with normal weight and even low weight can also suffer with diabetes.”
A lot of people just nod knowingly when I tell them I have type 2. They seem to be making two assumptions: that I’m fat because I eat crazy amounts of food, and that obesity caused the diabetes.
Diabetes reference bump. New to me but probably not new to my gal. Thanks.
I’m taking notes. Thanks.
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