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High-tech production of organs for transplantation is our future
BigThink ^ | 09/21/2021

Posted on 09/22/2021 7:55:23 AM PDT by BenLurkin

The first is three-dimensional (3D) bioprinting, which uses “bio-ink,” a printable material made from a patient’s own cells, to print layer upon layer, creating tissue that will not be rejected by the recipient. But in progressing from tissue to a complex organ, one critical challenge has been how to get blood to flow to keep the cells alive, and researchers have devised a number of approaches to this. They include threading tiny channels through the organ, where blood vessels develop when implanted in animals, or seeding channels with the endothelial cells that line the inside of blood vessels.

A second approach to providing a sufficient supply of organs for transplantation is genetically engineering animals — most often, pigs — so that their transplanted organs will not be rejected. In effect, it uses genetic engineering to grow “humanized” tissues and organs in animals. There was a breakthrough with this approach in 2018, when scientists used gene editing to create hybrid embryos containing both human and sheep cells.

There is considerable research underway to create lines of pigs for transplantation, but there is also controversy about the extent of genetic modification that will be necessary to both avoid rejection and ensure the absence of harmful pathogens. Therefore, it will be interesting to see at what stage of research and which genetic constructions regulators allow for the first clinical trials.

The FDA unveiled in 2018 the Plant and Animal Biotechnology Innovation Action Plan, which includes a pilot project — the Veterinary Innovation Program — similar to the breakthrough designation for drugs that is supposed to offer guidance and assistance by FDA experts to sponsors seeking approval of animal cell-based or biotech products.

(Excerpt) Read more at bigthink.com ...


TOPICS: Weird Stuff
KEYWORDS: bioprinting; organ; transplantation

1 posted on 09/22/2021 7:55:23 AM PDT by BenLurkin
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To: BenLurkin

Through the wonders of genetics, they will distort nature for profit. Expect humans created in the laboratory JUST for their organs. Won’t happen? Oh yes it will!

China already “harvests” organs for profit. Do they pick people with a low social score first? Don’t put it past them!

Or maybe not. Maybe they will stop when they have perfected the technique of growing organs in the laboratory without a human. They’re already doing this. A quick Google search surprised even me!


2 posted on 09/22/2021 8:15:36 AM PDT by I want the USA back (Dethrone the ruling elite. Redistribute their wealth. Take away their power. Annul their privileges.)
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To: BenLurkin

3 posted on 09/22/2021 8:18:49 AM PDT by Bloody Sam Roberts (If Liberals had a conscience, they wouldn't be Liberals.)
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To: Bloody Sam Roberts

I was thinking of Clonus starring Peter Graves.


4 posted on 09/22/2021 8:23:41 AM PDT by wally_bert (I cannot be sure for certain, but in my personal opinion I am certain that I am not sure.)
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To: BenLurkin

Grown is axolotl tanks?...............


5 posted on 09/22/2021 8:24:10 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: I want the USA back

“Through the wonders of genetics, they will distort nature for profit”

It turns out that if you live in the U.S. that’s the system! We call it capitalism! If you don’t like it you can always move to China, Cuba, or Venezuela.

There are over 500,000 people on dialysis in this country alone. The government pays for each and every one of these treatments, usually three times a week, to keep these people alive.

Are you suggesting that we (the taxpayers) continue to pay that or should we look for better ways of keeping these people alive. Maybe you prefer to just let them die.

I get to vote, too. I vote to keep them alive and look for better medical solutions.


6 posted on 09/22/2021 8:32:25 AM PDT by icclearly
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To: BenLurkin

trans-humanism is coming. The elite will live for 200 years while the rest of us die younger all the time.


7 posted on 09/22/2021 8:32:26 AM PDT by Pollard (Some people like to argue just to argue.)
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To: Pollard

I’ve always said that if immortality (or great life extension) is perfected, it will have to be the province of an exclusive and secret club. Otherwise, the masses would tear the immortals limb from limb out of jealousy.

Also, if everyone lives forever, what do we do about the children?


8 posted on 09/22/2021 9:02:57 AM PDT by Pearls Before Swine (FJB)
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To: BenLurkin

From the same bunch that brought us the genetically modifying CCP-Coronavirus ‘vaccines’. Sure, good plan!

Maranatha!


9 posted on 09/22/2021 9:10:11 AM PDT by A Formerly Proud Canadian (Ceterum autem censeo Justinius True-dope-us esse delendam)
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To: Pearls Before Swine
Also, if everyone lives forever, what do we do about the children?

Grow them in a lab for organ donor purposes but keep them in a coma until they're of no more use. Then make soylent green out of them to feed the servants.

10 posted on 09/22/2021 9:13:44 AM PDT by Pollard (Some people like to argue just to argue.)
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