Posted on 07/30/2021 1:16:11 AM PDT by tired&retired
“Explanation how ADE works and the future perils it may bring.
For a vaccine to work, our immune system needs to be stimulated to produce a neutralizing antibody, as opposed to a non-neutralizing antibody. A neutralizing antibody is one that can recognize and bind to some region (‘epitope’) of the virus, and that subsequently results in the virus either not entering or replicating in your cells.
A non-neutralizing antibody is one that can bind to the virus, but for some reason, the antibody fails to neutralize the infectivity of the virus. This can occur, for example, if the antibody doesn’t bind tightly enough to the virus, or the percentage of the surface area of the virus covered by the antibody is too low, or the concentration of the antibody is not high enough. Basically, there is some type of generic binding of the antibody to the virus, but it fails to neutralize the virus.
In some viruses, if a person harbors a non-neutralizing antibody to the virus, a subsequent infection by the virus can cause that person to elicit a more severe reaction to the virus due to the presence of the non-neutralizing antibody. This is not true for all viruses, only particular ones. This is called Antibody Dependent Enhancement (ADE), and is a common problem with Dengue Virus, Ebola Virus, HIV, RSV, and the family of coronaviruses. In fact, this problem of ADE is a major reason why many previous vaccine trials for other coronaviruses failed."
(Excerpt) Read more at sciencewithdrdoug.com ...
While this article is a lead in to entice us to subscribe to his newsletter, I found it very informative on its own.
Thanks - saving for later. Appears to be just the right mix of science and layman’s terms for me to understand it!
Per the article:
“a neutralizing antibody can subsequently transition to non-neutralizing antibody when encountering a different strain of the virus.”
“The exact mechanism of ADE in SARS is not known, but the leading theory is described as follows:
In certain viruses, the binding of a non-neutralizing antibody to the virus can direct the virus to enter and infect your immune cells. This occurs through a receptor called FcγRII. FcγRII is expressed on the outside of many tissues of our body, and in particular, in monocyte derived macrophages, which are a type of white blood cell.
In other words, the presence of the non-neutralizing antibody now directs the virus to infect cells of your immune system, and these viruses are then able to replicate in these cells and wreak havoc on your immune response. “
This is misinfprmation contrary to the diktatae of the Biden Hegemony.
Read it at your pwn risk, the thought police may come to remove it from your brain.
But this is exactly why many will not take the mRNA vaccine.
But we do have alternatives which have been censored by the Swamp, this is one:
Now , while we have a window of relative health, we must turn to drug therapy for prophylaxis.
Ivermectin is your friend:
Why do you think many Freepers are stocked up with Ivermectin and the necessary sister drugs?
Easy to order right here:
Ziverdo Kit: https://www.ziverdokit.store/
Or order the Ivermectin and follow the Dr. Pierre Kory protocols:
https://covid19criticalcare.com/
To order:
****************************************
****************************************
The Ziverdo Kit
Ziverdo kit (Zinc, Ivermectin, and Doxycycline) is a triple combination of active drugs at their effective doses. You might wonder why you have a supplement like a zinc tablet, an anti-parasitic agent, and an antibiotic in a kit. Well, it is a matter of research, and you can be sure that the best would be what the INDIAN FDA would approve.
Ivermectin, one of the Ziverdo kit constituents, has been an agent employed to treat several parasitic infections. It is indicated for use at the appropriate dosage, but safety at a higher dosage has not been established. Some have reported visual defects at higher doses. You may be curious enough to ask the benefit you stand to gain from the triple therapy of the Ziverdo kit. Yes, it does attack organisms of which makes it an excellent anti-viral agent. Ziverdo kit has an impressive efficacy on viruses, making it logical for its use in Dengue, Yellow fever, sindbis virus. Ivermectin usually comes in a dose of 3-6mg, but in the Ziverdo kit, the dose is increased to 12mg dispersible tablet for efficacy.
Zinc is another essential drug in the triple combination, rightly referred to as a supplement; zinc tablet has been used in different conditions such as diarrhea to reduce bowel movement. You might begin to wonder how that has to do with the virus. Yes, zinc tablet has a significance at a higher dose. It is employed at a lower dose in diarrhea cases, especially for babies who take a Zinc tablet of 20mg daily. Zinc is an excellent immune booster at a higher dose and has been recommended as a dietary supplement but not at an amount higher than the recommended dietary intake. The kit has Zinc acetate, which is equivalent to 50mg elemental zinc.
Doxycycline is a well-known drug used for several bacterial infections. Its use has benefited individuals who suffer viral infections due to doxycycline activity on RNA viruses. One of the reasons why the triple therapy of the Ziverdo kit is relevant is the anti-inflammatory activity of doxycycline. One of the most life-threatening symptoms of the Virus is hyper-inflammation of the airways, common among non-survivors of the Virus illness. Ziverdo kit has 100mg of doxycycline, which is the standard dose of the drug.
How Ivermectin works:
“Ivermectin docks to the SARS-CoV-2 spike receptor-binding domain attached to ACE2”
“This can cause a hyperinflammatory response, a cytokine storm, and a generally dysregulation of the immune system that allows the virus to cause more damage to our lungs and other organs of our body. “
I agree with you that Ivermectin looks good as a treatment.
However, it is important to understand the greater picture that is already unfolding.
Science does not stop at “It Works.” Science investigates why it does or does not work in order to find better solutions.
“For example, rhesus macaques who were vaccinated with the Spike protein of the SARS-CoV virus demonstrated severe acute lung injury when challenged with SARS-CoV, while monkeys who were not vaccinated did not.
Similarly, mice who were immunized with one of four different SARS-CoV vaccines showed histopathological changes in the lungs with eosinophil infiltration after being challenged with SARS-CoV virus. This did not occur in the controls that had not been vaccinated.
A similar problem occurred in the development of a vaccine for FIPV, which is a feline coronavirus.”
“A major trigger for ADE is viral mutation. Changes to the amino acid sequence of the Spike Protein (which is the protein on the virus that facilitates entry into our cells via the ACE2 receptor) can cause antigenic drift.
What this means is that an antibody that was once neutralizing can become a non-neutralizing antibody because the antigen has slightly changed.
Therefore, mutations in the Spike protein that naturally occur with coronaviruses could presumably result in ADE. Since these future strains are not predictable, it is impossible to predict if ADE will become a problem at a future date.”
Could this be why my response to the J&J vaccine was severe as I already had Covid-19 a year earlier?
Science does not stop at “It Works.” Science investigates why it does or does not work in order to find better solutions.>>>>>>>>>>>
Yes, true when scientists are not living in fear of infection brought about by the use of such therapy as Ivermectin.
Dr. Pierre Kory approves of this message:
https://www.youtube.com/watch?v=eeYoXGoh96w
How Ivermectin works:
“Ivermectin docks to the SARS-CoV-2 spike receptor-binding domain attached to ACE2”
“it is much more likely that the vaccine-induced antibodies can be rendered as non-neutralizing antibodies, because the entire virus is not coated in antibodies, only the portion that was used to develop the vaccine.”
i.e. the spiked protein
Bttt
It is not sufficient to understand what works from our own perspective to win a war.
We must also understand our opposition’s plan better than they do in order to avoid the obstacles sowed by our opposition’s actions.
Per the article:
“It would be the biggest blunder of the century to see the fatality rate of this virus increase in the years to come because of our sloppy, haphazard, rushed efforts to develop a vaccine with such a low threshold of safety testing and the prospect of ADE lurking in the shadows.
I would hope (and this is a big hope), that this vaccine WILL NOT BE MANDATORY.”
The caps were in the original text.
Back in June, a medical study out of Cleveland came out and it laid this odd problem down. There were increasing numbers of people who had Covid...then over the next few months...were displaying dementia-like problems (they weren’t going away).
It would a crazy mess if we wake up in 2023...to find a national trend that 10-percent of the people who contracted the disease now had a spiraling trend toward dementia.
2011 Article:
Investigation of Antibody-Dependent Enhancement (ADE) of SARS coronavirus infection and its role in pathogenesis of SARS
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019510/
“our data suggested that SARS-CoV is able to enter human immune cells via an antibody-mediated pathway and immunological consequences of such infection are under investigation (productive replication, cytokines secretion profile and cell death etc). Our data raise reasonable concerns regarding the use of SARS-CoV vaccine in humans and pave the way to further studies focusing on the role of immune-mediated infection phenomenon during SARS pathogenesis.”
The above research article warning of ADE in human Covid vaccines was presented in 2010.
Institut Pasteur International Network Annual Scientific Meeting
22–23 November 2010
Hong Kong
We must also understand our opposition’s plan better than they do in order to avoid the obstacles sowed by our opposition’s actions.>>>>>>>>>>>>>>>>>>
Good for you.
Ivermectin will also remedy ADE.
Read it here:
How Ivermectin works:
“Ivermectin docks to the SARS-CoV-2 spike receptor-binding domain attached to ACE2”
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.