Free Republic
Browse · Search
General/Chat
Topics · Post Article

To: tired&retired

2011 Article:

Investigation of Antibody-Dependent Enhancement (ADE) of SARS coronavirus infection and its role in pathogenesis of SARS

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019510/

“our data suggested that SARS-CoV is able to enter human immune cells via an antibody-mediated pathway and immunological consequences of such infection are under investigation (productive replication, cytokines secretion profile and cell death etc). Our data raise reasonable concerns regarding the use of SARS-CoV vaccine in humans and pave the way to further studies focusing on the role of immune-mediated infection phenomenon during SARS pathogenesis.”


18 posted on 07/30/2021 2:11:19 AM PDT by tired&retired (Blessings )
[ Post Reply | Private Reply | To 16 | View Replies ]


To: tired&retired

The above research article warning of ADE in human Covid vaccines was presented in 2010.

Institut Pasteur International Network Annual Scientific Meeting
22–23 November 2010
Hong Kong


19 posted on 07/30/2021 2:14:28 AM PDT by tired&retired (Blessings )
[ Post Reply | Private Reply | To 18 | View Replies ]

To: tired&retired

The warnings are there. This is a March 2020 Journal article:

Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks for Antibody-Dependent Enhancement (ADE)

https://www.preprints.org/manuscript/202003.0138/v1

“Findings: Non-neutralizing antibodies to variable S domains may enable an alternative infection pathway via Fc receptor-mediated uptake.

This may be a gating event for the immune response dysregulation observed in more severe COVID-19 disease. Prior studies involving vaccine candidates for FCoV5,6 SARS-CoV-17-10 and Middle East Respiratory Syndrome coronavirus (MERS-CoV) 11 demonstrate vaccination-induced antibody-dependent enhancement of disease (ADE), including infection of phagocytic antigen presenting cells (APC).”

“Interpretation: Safety testing of COVID-19 S protein-based B cell vaccines in animal models is strongly encouraged prior to clinical trials to reduce risk of ADE upon virus exposure.”


21 posted on 07/30/2021 2:22:46 AM PDT by tired&retired (Blessings )
[ Post Reply | Private Reply | To 18 | View Replies ]

Free Republic
Browse · Search
General/Chat
Topics · Post Article


FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson