Posted on 06/25/2021 12:37:42 PM PDT by Red Badger
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues.
The study, published in the International Journal of Molecular Sciences, is the first to show the pathogenic effects of some of the most widely used artificial sweeteners—saccharin, sucralose, and aspartame—on two types of gut bacteria, E. coli (Escherichia coli) and E. faecalis (Enterococcus faecalis).
Previous studies have shown that artificial sweeteners can change the number and type of bacteria in the gut, but this new molecular research, led by academics from Anglia Ruskin University (ARU), has demonstrated that sweeteners can also make the bacteria pathogenic. It found that these pathogenic bacteria can attach themselves to, invade, and kill Caco-2 cells, which are epithelial cells that line the wall of the intestine.
It is known that bacteria such as E. faecalis which cross the intestinal wall can enter the blood stream and congregate in the lymph nodes, liver, and spleen, causing a number of infections including septicaemia.
This new study discovered that at a concentration equivalent to two cans of diet soft drink, all three artificial sweeteners significantly increased the adhesion of both E. coli and E. faecalis to intestinal Caco-2 cells, and differentially increased the formation of biofilms.
Bacteria growing in biofilms are less sensitive to antimicrobial resistance treatment and are more likely to secrete toxins and express virulence factors, which are molecules that can cause disease.
Additionally, all three sweeteners caused the pathogenic gut bacteria to invade Caco-2 cells found in the wall of the intestine, with the exception of saccharin which had no significant effect on E. coli invasion.
Senior author of the paper Dr. Havovi Chichger, Senior Lecturer in Biomedical Science at Anglia Ruskin University (ARU), said: "There is a lot of concern about the consumption of artificial sweeteners, with some studies showing that sweeteners can affect the layer of bacteria which support the gut, known as the gut microbiota.
"Our study is the first to show that some of the sweeteners most commonly found in food and drink—saccharin, sucralose and aspartame—can make normal and 'healthy' gut bacteria become pathogenic. These pathogenic changes include greater formation of biofilms and increased adhesion and invasion of bacteria into human gut cells.
"These changes could lead to our own gut bacteria invading and causing damage to our intestine, which can be linked to infection, sepsis and multiple-organ failure.
"We know that overconsumption of sugar is a major factor in the development of conditions such as obesity and diabetes. Therefore, it is important that we increase our knowledge of sweeteners versus sugars in the diet to better understand the impact on our health."
Explore further
More bad news for artificial sweetener users More information: Aparna Shil et al, Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria, E. coli and E. faecalis, International Journal of Molecular Sciences (2021). DOI: 10.3390/ijms22105228 Provided by Anglia Ruskin University
Thanks for pointing me to the info!!
What can I say. Rather than taking responsibility for my lack of reading comprehension, I'll just blame it on my lack of patience. LOL!!
Hmmm. Please provide link
It was Clinton that received a large donation to his ‘charitable’ organization to get aspartame approved. That nastiness nearly killed me.
You aren’t going to like my history lesson.
Donald Rumsfeld was CEO of Searle that invented Aspartame and as head of Reagan transition team he allegedly suggested the new FDA head that approved aspartame
You’ve had it in gummies and things. More than about four and yes, you’ll have problems.
I have that product. Bought from Amazon, can’t remember name at the moment.
Well, it is different for everyone, but you fan know your cut off by using keto strips occasionally.
Boy that article is the biggest buttload of bunkum and blather I have read in a long time.
These sweeteners have been in use for 25 to 40 years now. And yet, here we are, still alive.
I’m very careful with my dogs. The alcohol sugars can cause GI distress in some people, but I’ve used Xylitol and Erythritol without issue. I find Xylitol to be better tasting and dissolves better.
Good for me. If it protects me against the ‘Rona’ while sweetening my tea that’s a plus.
I do not care for the cooling sensation erythromycin imparts to the taste. I have some, but use it rarely. I prefer to use Isomalt with a little monk fruit powder, as isomalt is only 75% as sweet as sugar. When I make keto ice cream, I make sweetened condensed milk from evaporated milk and isomalt, cooked til the consistency of condensed milk, cool it down to room temperature (or lower), whip 1 quart of heavy cream til soft peaks form, add a dash of salt, a teaspoon of vanilla, and whatever flavoring and nuts I want, then mix in the condensed milk and a little xanthan gum, taste it for sweetness, and mix in a little monk fruit powder if needed, and stick it in the freezer overnight. Makes wonderful low carb ice cream! Makes about 10 cups, 6.44g carbs, 38g fat, and 4.5g protein per cup.
Aspartame was approved by the Obama Administration in its first month of power.
Interesting
Aspartame was first approved for use in foods in 1981 and in beverages in 1983. Just looked it up. :-)
Then saccharine.
(Something in the news that we’d never expect approval).
Indicative of corruption
..
And to think all that money I wasted on dope when I was young.............................
Were the drinks made in Korea?.........................
Nothing is perfect, but I will take my chances with the REAL stuff.
Table Sugar, 1 Level Teaspoon (4g) (1 tsp) Calories: 15
Nope, straight from the USA via the commissary.
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