Ivermectin: Modes of action against SARS-CoV-2 virus replication (Mody et al)
Posted on 05/19/2021 12:37:15 PM PDT by SeekAndFind
New insights into the mode of action of ivermectin against the novel SARS coronavirus.
The previously discussed, WHO-sponsored meta-analysis of ivermectin against covid-19 has now been published as a preprint. It found a highly significant 75% reduction in covid mortality, based on randomized controlled trials only, and will be continually updated with additional trial results.
To date, the mode of action of ivermectin against SARS-CoV-2 has remained somewhat of a mystery. Early studies indicated that ivermectin may inhibit viral protein transportation. But a new US-Canadian study, published in Nature Communications Biology, found that ivermectin is highly effective (>90%) in inhibiting the main enzyme (3CLpro) involved in the replication of SARS-CoV-2 and other RNA viruses (see the chart above).
Another study, submitted to the Journal of Structural Chemistry, found that ivermectin is binding to the spike protein of SARS-CoV-2 and thus may act as a generic antibody. This might explain why ivermectin appears to be highly effective even as a prophylaxis against SARS-CoV-2 infection.
Nevertheless, many patients, and even doctors, continue to be denied access to low-cost and safe ivermectin, especially in Western countries. Others are paying obscenely overcharged prices, visit dubious online merchants, or resort to animal-grade products. If ivermectin is not available locally, it may instead be bought from certified Indian pharmaceutical exporters on Indiamart. However, please note that some countries may not allow its importation.
100 tablets of 12mg ivermectin, enough to treat up to 50 people, cost about $50. And even if SARS-CoV-2 continues to mutate, ivermectin, targeting its replication, should remain effective. The same applies to other early treatment drugs targeting virus entry, replication, or disease progression.
Note: Patients are asked to consult a doctor.
Ivermectin: Modes of action against SARS-CoV-2 virus replication (Mody et al)
https://www.amazon.com/Apple-Flavored-Ivermectin-Paste-Pack/dp/B00S8LL17E
I’ve been on it for months. Priceis going up! Word is out.
“Anyone trying that should have some good scales to measure their dose.”
No, not so. Dose is very forgiving. Double it of you want, no problem. Just use the same amount as a horse,adjusted for your weight. A blob about the size of toothpaste on a brush. I swallow it whole. Not much taste.
How often do you take it? I have read different protocols from different doctors.
Have an illuminated holy family statue of Joseph and Mary holding baby Jesus and a sign reading FOR AMERICA PRAY THE ROSARY facing the state highway which is our access and fronts our property lighted by red, white, and blue led lights.Plus a
lighted flag close by.
One of the prayers I’ve been saying is that That stuff works where ever its being used.
Have an illuminated holy family statue of Joseph and Mary holding baby Jesus and a sign reading FOR AMERICA PRAY THE ROSARY facing the state highway which is our access and fronts our property lighted by red, white, and blue led lights.Plus a
lighted flag close by.
One of the prayers I’ve been saying is that That stuff works where ever its being used.
Tractor Supply Company...
~~~~~~~~~~~~~~~~~~~~~~~
I’ve hear this mentioned several times here on FR and I’ve wondered about a few things...
- Not that they won’t give it to a customer but do they ever ask “so how many horses do you have?” or something to that effect...
- I’m assuming that there must be a real run on this product... are they mentioning anything about shortages or does TSC always seem to have plenty of stock?
- On a different matter, do you know what the shelf life is for ivermectin? I wanted to have some handy just in case I needed some on short notice and and my doctor wouldn’t write a prescription for me....
I’ve never been asked about having horses. It’s perfectly legal to buy and the store couldn’t care less if you’re buying it for yourself.
The expiration date on my new box is February 2023.
We keep the tube type, in our barn, and I had grabbed a couple of boxes, before we had the Rx (pills) version....
Looks like it lasts (if you go by their expiration date) about two years.
BTTT!!!
Regardless, it works. The ivermectin protocol worked for our family. We got ours from India. India exports pharmaceuticals to the entire world, by the way
Bttt.
5.56mm
Price has gone up! $14.00 for my last batch. Works for Lyme Disease too. That is why I bought the first batch.
Great Find. If that's true, then I think Ivermectin would likely interfere with the vaccines developing a response, if you are taking it when you are vaccinated.
But as a first line of defense it should be great.
Disclaimer: DannyTN is not an immunologist but he plays one on FR.
My horse said it's not bad, but it doesn't compare to apples. He thinks they should make it in chocolate.
Doc in Idaho talking about Vitamin D and Ivermectin.
https://robertdavidsteele.com/dr-ryan-cole-ceo-m-d-of-cole-diagnostics-regarding-covid-vaccine-treatments/
Every 2 weeks, per protocol. Sometimes I take another in between. Also on HCQ, same deal.
the REAL problem with 1.8% ivermectin horse-paste is that NONE of the manufacturers specify what the other 98.2% ingredients are, and there are zero standards about what other ingredients may or may not be included ...
An overe dosing of Ivermectin is not likely if you divide the 1200 poind horse dose into six equal doses. You end up with the amount needed for a 200 pound pereson in each dose.
BTTT
You don’t worm foals.
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