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Israeli Scientist Claims to ‘Reverse’ Aging in Blood Cells
The Times of Israel ^ | Nathan Jeffay

Posted on 04/02/2021 10:58:54 PM PDT by nickcarraway

‘This means we can start to look at aging as a reversible disease,’ says Prof Shai Efrati; top geriatrician says he is skeptical, and raises concerns

An Israeli doctor says he has brought about physical changes in human blood cells that “reverse” aging, using an oxygen therapy.

Shai Efrati reported in a peer-reviewed journal article published on November 18 that his research team’s 60-day therapy lengthened telomeres, the structures found at the ends of chromosomes, on average by more than a fifth.

He claims this represents a “holy grail” in the battle against aging. However, some other physicians have reservations, and are concerned that he may be opening a Pandora’s box that could end up causing health problems.

Get The Start-Up Israel's Daily Start-Up by email and never miss our top storiesFREE SIGN UP “We try to address aging with physical exercise and changes to diet, but this only slows decline,” Efrati told The Times of Israel. “We’re showing that we can actually take the biological clock backwards and improve the quality of blood cells. This means we can start to look at aging as a reversible disease.”

The Tel Aviv University associate professor said that in the near future, large numbers of people could sign up for the therapy he gave to subjects in his trial: a course of sessions in a pressurized — or hyperbaric — chamber, breathing pure oxygen for some of the time.

The non-profit Sagol Center for Hyperbaric Medicine and Research at the Shamir Medical Center near Rishon Lezion, which he directs, offers its oxygen protocol to businesses outside Israel. It is being sold at the Aviv Clinic at a retirement village in Florida, which offers it as an answer to aging. Efrati is medical adviser to the clinic.

Some other doctors say the claims should be treated with caution.

“I’m skeptical that one manipulation can reverse aging, a complicated process with many factors,” the leading geriatrician Yoram Maaravi, who is unconnected to the research, told The Times of Israel.

He said that telomeres are widely believed to be one of several factors that impact on aging, not a single factor, the changing of which can simply turn back time. And he argued that it is too early in telomere study to make bold declarations that lengthening them will address aging, as much of the knowledge today consists of inferences for humans drawn from studies of mice.

Maaravi, chief physician at Hadassah Medical Center’s geriatric rehabilitation department, and head of home rehabilitation in Jerusalem for the Clalit health fund, also said that if oxygen therapy is actually lengthening telomeres, it could be a development that backfires as so little is still known about them. “One time we see lengthened telomeres is with cancer,” he said. “Cancer cells have an enzyme that can lengthen them, and we have to be very careful about manipulating nature.”

Efrati reported that as well as elongating telomeres, his therapy led to a decrease in senescent cells, the population of which is thought to correlate to the onset of various diseases.

Maaravi said the impact of reducing such cells is not understood enough to be the basis for a claim to address aging. “Is removing senescent cells going to reduce aging?” he asked. “We don’t know yet.”

Professor Shai Efrati of the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center (courtesy of the Sagol Center) Efrati’s new study was written after he recruited 35 people aged 64-plus, and took blood samples. He then gave some of them a 60-day course of treatment, during which they spent stints in a hyperbaric chamber, breathing pure oxygen for some of the time.

In a previous study published in July, he claimed that the therapy improves cognitive function. In the latest research, he looked at telomeres, which are like protective caps at the ends of chromosomes. They get shorter with age and some studies indicate that their length can affect the pace of physical aging and onset of age-associated diseases.

He excluded results for nine of his participants from his telomere analysis, five because they did not meet baseline assessments and four because their blood samples were low quality. For the analysis of senescent cells he excluded 15 participants, five because they did not meet baseline assessments and 10 because their blood samples were low quality.

Among other study participants, there was an increase in telomere length, averaging more than 20 percent, and a reduction in senescent cells on a similar scale, Efrati reported.

“Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation,” said Efrati. “Our hyperbaric oxygen therapy protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level.”


TOPICS: Health/Medicine; Science
KEYWORDS: aging; health; hivaging; israel

1 posted on 04/02/2021 10:58:54 PM PDT by nickcarraway
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To: nickcarraway

“.... and men will seek death but will not be able to find it.”


2 posted on 04/02/2021 11:04:11 PM PDT by Safrguns
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To: nickcarraway

Playing God.
Not going to happen.
Short of perpetual stasis or suspended animation, human life was meant to be finite.
The sooner those seeking the fountain of youth, etc. figure this out, the better off we will all be as a species.


3 posted on 04/02/2021 11:04:17 PM PDT by cranked
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To: nickcarraway

bookmark


4 posted on 04/02/2021 11:11:51 PM PDT by GOP Poet (Super cool you can change your tag line EVERYTIME you post!! :D. (Small things make me happy))
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To: nickcarraway

I hope they do knees next!


5 posted on 04/02/2021 11:32:51 PM PDT by JoSixChip (2020: The year of unreported truths. )
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To: Safrguns

“.... and men will seek death but will not be able to find it.”

It is easy to find a bridge or an on-coming train....


6 posted on 04/02/2021 11:42:36 PM PDT by GraceG ("If I post an AWESOME MEME, STEAL IT! JUST RE-POST IT IN TWO PLACES PLEASE")
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To: Fred Nerks

An Israeli doctor says he has brought about physical changes in human blood cells that “reverse” aging, using an oxygen therapy. >>>>>>>>>>>>>>>>>>>>

The Fountain of Youth has been discovered?

Just get in the tank.

You can build one in your basement.


7 posted on 04/03/2021 2:48:36 AM PDT by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: cranked
human life was meant to be finite.

I went to a funeral once where the preacher said "We're meant to LIVE". I thought of that as a profound statement, since that really is how the human body is tuned. I ultimately think aging and death can be overcome, but there are HUGE consequences to doing so, e.g. no more generational shifts (although that one may be a good thing given how America has changed since the '60's)

No one can have as many babies as they can afford, how will the 200 year olds that have retired support themselves, what about those that have had joint replacements or stents (how will reversing the aging process help them) etc, etc. There will be a lot of unintended consequences that no one has thought of.

It will be painful in a lot of ways, despite the never ending human search for immortality, or at least a fountain of youth.

8 posted on 04/03/2021 4:31:12 AM PDT by Hardastarboard (Don't wish your enemy ill; plan it.)
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To: Candor7

You can build one in your basement.
_________________
I believe some celebrities already have them.


9 posted on 04/03/2021 4:46:49 AM PDT by KittyKares (I miss President Trump!)
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To: cranked

There is a time to live and a time to die. GOD has the final say.

However, in Matthew 24 it says as in the days of Noah, so will it be when the SON of man returns. Will today’s average lifespan be extended to the length of lifespans ‘as in the days of Noah’?


10 posted on 04/03/2021 5:08:48 AM PDT by stars & stripes forever (Blessed is the nation whose God is the Lord. (Psalm 33:12))
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To: Safrguns
“.... and men will seek death but will not be able to find it.”

That was the premise of a ABC TV series - it lasted 1 season although it was somewhat entertaining. It's currently on CW Seed app on Roku.


11 posted on 04/03/2021 5:13:14 AM PDT by newfreep (“Leftism, under all of its brand names, is a severe, violent & evil mental disorder.”)
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To: stars & stripes forever

You do realize that according to ancient kings lists and the sort, Kings were recorded to have lived (i.e.: ruled) for thousands and thousands of years, long before the Bible was written. You know the irony here, they all died, eventually.


12 posted on 04/03/2021 5:55:03 AM PDT by cranked
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To: cranked

We all have to go sometime, except for believers who are living when CHRIST appears in clouds of glory.

The generation who saw ISRAEL become a nation will see CHRIST’S return. Perhaps lifespans will be extended to bring in the final harvest.


13 posted on 04/03/2021 6:00:24 AM PDT by stars & stripes forever (Blessed is the nation whose God is the Lord. (Psalm 33:12))
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To: stars & stripes forever

Perhaps, even with faith, only time will tell.


14 posted on 04/03/2021 6:01:18 AM PDT by cranked
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