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What is Regeneron’s antibody cocktail? Here’s what we know about President Trump’s Covid-19 treatment
WAVY ^ | 10/02/2020 | by: Nexstar Media Wire

Posted on 10/02/2020 6:20:03 PM PDT by SeekAndFind

The White House said Friday that President Donald Trump remains “fatigued” after contracting COVID-19 and has been injected with an experimental antibody cocktail for the virus that has killed more than 205,000 Americans and spread to the highest reaches of the U.S. government.

Trump’s physician, Navy Commander Dr. Sean Conley, revealed on Friday the commander-in-chief received a dose of an experimental antibody cocktail by Regeneron that is in clinical trials.

“He completed the infusion without incident,” Dr. Conley said in the statement.

Dr. Conley said Trump “remains fatigued but in good spirits” and that a team of experts was evaluating both the president and first lady in regard to next steps.

Trump is also taking zinc, Vitamin D, melatonin and other medications.

The first lady, who is 50, has a “mild cough and headache,” Conley reported, and the remainder of the first family, including the Trumps’ son Barron, who lives at the White House, tested negative.

In a statement late Friday, Regeneron confirmed Trump was provided the REGN-COV2 antibody cocktail as part of a “compassionate use request,” which is when the Food and Drug Administration allows for unapproved treatments to be made available to treat ill patients when no other treatment is available.

The company’s compassionate use program defines it as being intended for patients with serious or life-threatening conditions who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials.”

What is Regeneron polyclonal antibody cocktail?

Trump is receiving a two-antibody combo drug that’s currently in late-stage studies from Regeneron Pharmaceuticals Inc. The company previously developed a successful treatment for Ebola using a similar approach.

It’s given as a one-time treatment through an IV.

Trump’s physician, Dr. Sean Conley, said the drug was being given “as a precautionary measure,” and that Trump also was taking zinc, vitamin D, an antacid called famotidine, melatonin and aspirin. None of those have been proven to be effective against COVID-19.

Trump apparently is not receiving hydroxychloroquine, a drug he widely promoted that has been shown in many studies to be ineffective for preventing or treating COVID-19.

Released earlier this week, the first data from a trial using Regeneron’s COVID-19 antibody cocktail is encouraging. The top dose of the treatment relieved symptoms more quickly than the placebo for patients not sick enough to be hospitalized.

The initial phase included 275 patients in the phased study. The most significant improvements were seen in patients who had not already mounted a natural response, the company said.

Jeanne Marrazzo, the director of the division of infectious diseases at the University of Alabama at Birmingham, told CNN the results appear “very promising.”

The company said the treatment is intended as a therapeutic substitute for a natural response to the virus. According to a news release, Regeneron said it is hoping to confirm their initial findings in a second group of patients.

“What I think is fascinating is that it shows that antibodies really matter and the antibody to the spike protein was really helpful, particularly when people made the antibodies themselves,” said Marrazzo. “Whether it’s antibody therapy or vaccine that target these proteins, it sounds like we are on the right track. I think that’s really encouraging.”

Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The blood of survivors is being tested as a treatment for COVID-19 patients because it contains such antibodies, but the strength and types of antibodies varies depending on each donor, and doing this on a large scale is impractical.

The drugs that Regeneron and other companies are testing are concentrated versions of specific antibodies that worked best against the coronavirus in lab and animal tests, and can be made in large, standardized doses.

They are being tested to treat newly diagnosed COVID-19 patients in hope of preventing serious disease or death, and to try to prevent infection in people at high risk of that such as nursing home residents and health workers.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: antibodycocktail; covid19; regeneron; trump
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1 posted on 10/02/2020 6:20:03 PM PDT by SeekAndFind
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To: SeekAndFind

Dr. Sean Conley - Shaken, not stirred


2 posted on 10/02/2020 6:21:50 PM PDT by dontreadthis (A TIMELINE OF TREASON on Profile Page)
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To: dontreadthis

Its synthetic antibody that should neutralize the virus.


3 posted on 10/02/2020 6:26:57 PM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: SeekAndFind

The president surely requested the treatment most likely to get him back to full-time duties and to campaigning the fastest.


4 posted on 10/02/2020 6:30:52 PM PDT by citizen (Women are from Venus and Men are from Mars. A,ll the other genders you make up are from Uranus.)
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To: SeekAndFind

Repeating the lies about vitamin D and zinc being ineffective again, I see.

CC


5 posted on 10/02/2020 6:36:35 PM PDT by Celtic Conservative (My cats are more amusing than 200 channels worth of TV.)
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To: dontreadthis

haha


6 posted on 10/02/2020 6:46:40 PM PDT by nuconvert ( Warning: Accused of being a radical militarist. Approach with caution.)
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To: SeekAndFind

Hopefully, President Trump’s doctors are reading threads here for the best medical advice for the President. /sarcasm.


7 posted on 10/02/2020 7:02:04 PM PDT by Meatspace
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To: SeekAndFind
If he's showing symptoms this quickly, he's at extreme risk. There is no other treatment to effectively eradicate a respiratory viral infection of this type.

I hope his doctors are either very smart or very lucky.

Wuhan Coronavirus: Propylene Glycol as Possible Therapy for Eradication of RTI and Prevention of Complications [vanity]

8 posted on 10/02/2020 7:02:41 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: Meatspace

No kidding — everyone here is a freaking expert. Its like a bunch of four year olds. But what about zinc. We need zinc. Definitely zinc. and Ionophores. Never mind the fact that he is at a world class institute with physicians who do not want to be the ones that off a president if nothing else.

The armchair idiocy herein is breathtakingly impressive.


9 posted on 10/02/2020 7:04:54 PM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: Celtic Conservative

I noticed that, too!

Here’s Dr. John Campbell’s report on a study showing almost astonishing effeciveness for Vitamin D (in its calcifidiol form):

https://www.youtube.com/watch?v=V8Ks9fUh2k8


10 posted on 10/02/2020 7:21:34 PM PDT by buridan
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To: buridan

correction: calcifediol


11 posted on 10/02/2020 7:26:40 PM PDT by buridan
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To: SeekAndFind

Trump apparently is not receiving hydroxychloroquine, a drug he widely promoted that has been shown in many studies to be ineffective for preventing or treating COVID-19.

____________________________________________

That ‘experts’ told him.


12 posted on 10/02/2020 7:27:28 PM PDT by TribalPrincess2U
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To: Meatspace

Love it!


13 posted on 10/02/2020 7:28:35 PM PDT by TribalPrincess2U
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To: gas_dr
The armchair idiocy herein is breathtakingly impressive.

Thank you! There are those among us who feel that they know it all after mulling over months of “World-o-Meter” graphs and naturopathic “studies” recommending high dosage vitamin C etc... I had the misfortune to speak with my neighbor the other day who insisted that we were currently losing 700 people a day in our state alone from Coronavirus. The actual number is 2 or 3 and often 0 with coronavirus and not from coronavirus.

Personally, I was fearful that President Trump would be pushing his doctors toward some of the “fad” treatments popular on conservative websites. I am glad that he appears to be following the advice and treatment of the top doctors in our country.

The only thing worse that I have read here on the subject of health are those pushing various high protein fad diets. We have people in their 80s here who are cutting out entire food groups, thinking that they can subsist on bacon, sausage, hamburger, protein bars and various high dosage dietary supplements. I always wonder if what we really have are trolls from DU intentionally trying to kill people by recommending ridiculous diets.

If you get sick take the advice of a doctor... and not some poster here who thinks that they know it all.

14 posted on 10/02/2020 7:30:52 PM PDT by fireman15
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To: Meatspace

“Hopefully, President Trump’s doctors are reading threads here for the best medical advice for the President. /sarcasm.”

Listen, if you’re going to encourage the Google Doctors here on FR we’re going to have to ask that your refrain from posting for a while. :)


15 posted on 10/02/2020 7:46:28 PM PDT by CodeToad (Arm Up! They Have!)
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To: SeekAndFind

How about do nothing but treat the symptoms. This sickness usually goes away without screwing around with it.


16 posted on 10/02/2020 7:47:23 PM PDT by CodeToad (Arm Up! They Have!)
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To: Celtic Conservative

You have two Drs here that say zinc doesn’t work. One said it has been shown not to work.

Dont care.

Doesnt hurt
I will take it.

With Green Tea or Quercetin.


17 posted on 10/02/2020 8:05:24 PM PDT by RummyChick
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To: fireman15

Do you believe the Dr is indicating he is taking Pepcid for Covid? Or just that he is taking Pepcid for heartburn


18 posted on 10/02/2020 8:07:47 PM PDT by RummyChick
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To: TribalPrincess2U

“Trump apparently is not receiving hydroxychloroquine, a drug he widely promoted that has been shown in many studies to be ineffective for preventing or treating COVID-19.”

HCQ is not ineffective. Our 35 year old son took it and quit coughing in 24 hours and was well in 3 days.


19 posted on 10/02/2020 8:08:04 PM PDT by Antipolitico
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To: fireman15

Amen. some of the medical advice I see here is incredibly bad and it I call it out I get told I know nothing. No skin off my teeth I just hope some poor soul is not foolish enough to try some of the advice I see here


20 posted on 10/02/2020 8:13:21 PM PDT by Mom MD
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