Posted on 09/08/2020 1:26:22 PM PDT by metmom
A closer look at the Bradykinin hypothesis
arlier this summer, the Summit supercomputer at Oak Ridge National Lab in Tennessee set about crunching data on more than 40,000 genes from 17,000 genetic samples in an effort to better understand Covid-19. Summit is the second-fastest computer in the world, but the process — which involved analyzing 2.5 billion genetic combinations — still took more than a week.
When Summit was done, researchers analyzed the results. It was, in the words of Dr. Daniel Jacobson, lead researcher and chief scientist for computational systems biology at Oak Ridge, a “eureka moment.” The computer had revealed a new theory about how Covid-19 impacts the body: the bradykinin hypothesis. The hypothesis provides a model that explains many aspects of Covid-19, including some of its most bizarre symptoms. It also suggests 10-plus potential treatments, many of which are already FDA approved. Jacobson’s group published their results in a paper in the journal eLife in early July.
(Excerpt) Read more at elemental.medium.com ...
Thanks for posting. Very interesting. But all of those people have behind them are facts and a supercomputer which is no match for politicians and Big Pharma money.
“Open the Pod Doors, HAL.”
A supercomputer cannot analyze anything.
People created a model based on observations and assumptions, and then wrote a program to test their model.
They then ran the program on a “supercomputer” (which will be a standard “desktop” computer maybe 20 years hence). The program produced a set of results based on the data provided.
The set of results were then interpreted.
Exactly so.
No computer can beat a chess master.
But a team of chess players who program a computer to play chess can beat a chess master.
The team beat the master...the computer is no smarter than a stone.
AI is a myth, simulated AI is real.
You can create a robot that can perform surgery but it will ALWAYS be the team of surgeons and programmers that are actually doing the surgery.
There is a huge difference between intelligence and a programmed simulation of intelligence and there always will be.
Silly Americans. While we dick around with a super computer, a Nigerian trained black female doctor in Houston has kicked our asses and figured it out months ago, and she’s the one who gets shunned.
It is interesting in the sense, as many others have pointed out, this is more of a vascular disease than one simply impacting the lungs.
What boggles my mind is how efficient this thing is. Folks can be asymptomatic. It attacks the blood vessels. It impacts the lungs but in a fashion outside the medical norm. It does a lot of damage in a number of ways.....all things we have seen before....except this has a host of them. I am not a scientist but it seems odd to me, this evolved to thread the needle in so many specific ways....unlike anything previously. Unless there is some intelligent design behind it.
I think you’re off a bit.
It’s certainly possible to do a classification model across a variety of known treatments correlated against analyzed characteristics of an illness. Likely unsupervised learning from the snippet. Math-intensive, thus throwing lots of compute power at it.
“Writing a program” to test hypotheses is what one might do with each of these potential treatments (although it’s really applying regression against control vs treatment, not writing any custom code).
Hmmmn.
But which of the bradykin did it?
Russha, Russha, Russha ...... anyone?
:^)
But those 10-plus treatments not FDA-approved for COVID-19, therefore, they're dangerous.
/sarc
Bwahahaha, Bob, I think you have hit upon the heart of America’s problem!
When start your reasoning with an error, guess what you results are likely to be: “No computer can beat a chess master.” Already been done, dude.
“AI is a myth, simulated AI is real.”
Semantics. AI attempts to replicate our brains.
“AI is a myth, simulated AI is real.”
Semantics. AI attempts to replicate our brains.
“You can create a robot that can perform surgery but it will ALWAYS be the team of surgeons and programmers that are actually doing the surgery.”
Hey now, on behalf of all computer programmers I am going to need to ask you to hush up before we all have to start buying malpractice insurance!
“A supercomputer cannot analyze anything.
People created a model based on observations and assumptions, and then wrote a program to test their model.
They then ran the program on a “supercomputer” (which will be a standard “desktop” computer maybe 20 years hence). The program produced a set of results based on the data provided.
The set of results were then interpreted.”
Bingo. My thoughts exactly. And the results were interpreted by humans.
Sure.
Where would we be without the FDA to *protect* us?
Can you say *Vioxx*?
Artificial Flowers aren’t Flowers
and
Artificial Intelligence isn’t Intelligence
they are but mere shadows of what they can only pretend to be.
7
great article.
thanx for posting the link
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