Posted on 04/13/2020 3:21:05 PM PDT by Pining_4_TX
On Saturday the Food and Drug Administration approved the use of two antimalarial drugs, hydroxychloroquine and a related medication, chloroquine, for emergency use to treat COVID-19. The drugs were touted by President Trump as a game changer for COVID-19.
However, a study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. The study comes on the heels of two others - one in France and one in China - that reported some benefits in the combination of hydroxychloroquine and azithromycin for COVID-19 patients who didnt have severe symptoms of the virus.
I am a medicinal chemist who has specialized in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven. I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.
There are already other clinical studies that showed it is not effective against COVID-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving people false hope. The latter has led to widespread shortages of hydroxychloroquine for patients who need it to treat malaria, lupus and rheumatoid arthritis, the indications for which it was originally approved.
(Excerpt) Read more at acsh.org ...
This site is not a liberal lefty site, so they are not reporting this to attack the president.
Tell Boris Johnson to report back to ICU.
Does not erase the numerous positive results. We already know it only works in some cases.
Small study is right! Geesh 11 patients? And where’s the ZINC????
Hey, I’m not saying this. I’m only posting it for info. If it works, that’s great. I hope it does.
The new study, of which the abstract was released today, was performed at IHU Méditerranée Infection, Marseille, France. A cohort of 1061 COVID-19 patients, treated for at least 3 days with the Hydroxychloroquine-Azithromycin (HCQ-AZ) combination and a follow-up of at least 9 days was investigated.
Key findings are:
No cardiac toxicity was observed.
A good clinical outcome and virological cure was obtained in 973 patients within 10 days (91.7%).
A poor outcome was observed for 46 patients (4.3%); 10 were transferred to intensive care units, 5 patients died (0.47%) (74-95 years old) and 31 required 10 days of hospitalization or more.
The authors conclude that:
The HCQ-AZ combination, when started immediately after diagnosis, is a safe and efficient treatment for COVID-19, with a mortality rate of 0.5%, in elderly patients. It avoids worsening and clears virus persistence and contagiosity in most cases.
...new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body.
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HCQ is *not* intended as a virus killer. The purpose is to reduce the ability of the Corona virus to replicate in the patient.
a full sized clinical trial was just published in France...
over 1000 participant patients.
91.7 percent successful recovery rate in just 3 days
of these cheap and plentiful little pills
to my way of reckoning, that’s no failure
Never believe females with hyphenated names. ;-)
I pretty much expected this from the trials. Thousands of doctors, and multiple country’s are all wrong about what they have found with using HCQ. The Trial is rigged. Trials are rigged all the time.
No zinc?
yep
What is the point of all these “trials” coming out of the woodwork? Some work would be good to see who it might hurt.
Shouldn’t all of the rest of these folks be working on developing superior alternatives and then testing those?
She appears to have conflicts.
Medical writers should never have them or should disclose if any appearance of conflict. According to comments on article a little skepticism seems appropriate.
well, it is wrong.
She was already in a posted article a few weeks ago pooping on HCQ. Look at her hyphenated name. She probably has a RESIST bumper sticker on her Prius.
So those with concerns about HCQS should refuse to allow it to used in their treatment if the contract the illness.
it's funny, but this is a small, non-peer-reviewed study, without Zinc as recommened by the studies which showed positive effects.
I wonder how many boxes of Donuts Nancy Pelosi and Bill Gates promised her...
And when they say a “small” study, they mean 11 people. From the actual medial study...
“There were 7 men and 4 women with a mean age of 58.7 years (range: 20-77), 8 had significant comorbidities associated with poor outcomes (obesity: 2; solid cancer: 3; hematological cancer: 2; HIV-infection: 1).”
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