Posted on 04/06/2020 6:58:34 PM PDT by nickcarraway
A recent collaborative study conducted by a team from Monash University and the Doherty Institute in Australia has found that a commonly used anti-parasitic drug could halt the incubation process of the novel coronavirus and potentially cure Covid-19 positive patients of any ailments caused by the virus.
The study showed that the drug available globally called Ivermectin was able to kill SARS-CoV-2, the coronavirus that causes Covid-19, growing in cell culture within 48 hours.
It must be noted, however, that the study was conducted in vitro - in a controlled environment outside a living organism - and that more credible data would be obtained pending clinical trials on human subjects.
"We report here that Ivermectin, an FDA-approved anti-parasitic previously shown to have broad-spectrum antiviral activity in vitro, is an inhibitor of the causative virus," the report stated.
The drug was previously shown to have been effective against a wide variety of viruses, including HIV, dengue, influenza and the Zika virus, the study claimed.
Kylie Wagstaff, a scientist at the Monash Biomedicine Discovery Institute who led the study, said the optimistic results of the study had warranted the possibility of human trials, which would yield more credible information regarding the drug's efficacy within living cells.
"We found that even a single dose [of Ivermectin] could essentially remove all viral RNA [ribonucleic acid] by 48 hours and that even at 24 hours there was a really significant reduction in it," Wagstaff said in the report.
"We need to figure out now whether the dosage that can be used in humans will be effective - that's the next step,"
Ivermectin had presumably inhibited the viral process that "dampened down" the host cells' ability to kill it, Wagstaff said.
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However, the specific ways in which Ivermectin overrides such viral processes have yet to be discovered, she added.
Many countries, including Indonesia, are scrambling to find possible remedies for the deadly virus as scientists fast-tracked research on a vaccine.
President Joko "Jokowi" Widodo announced last month that the government had been preparing medicine, including 3 million doses of chloroquine, which he described as "having been proven to cure Covid-19 in other countries".
However, health experts have since raised concerns over the risks inherent in self-medication using choloroquine phosphate - an antimalarial drug - as they claimed the medicine had an array of dangerous side effects including diarrhoea, breathing difficulties, weakened muscles and mental disorders.
Oh, yeah, dog wormer! 9 out of 10 flubronies approve!
but but but you do - it's not a vaccine!!! You pro-vaxxer- we all must fall in line with the great know it all government doctor we must take a vaccine.
Who cares how it works, you say, but wait, you wrote this... Anti-vaxxers should take note about that historic polio legacy solution vaccine propaganda...we all need to line up and let big drug stab are ass to save our ass.
Then you want to know about my children, if they've been protected by your all powerful mighty vaccine saying this... No, but when your children die of whooping cough or are crippled from polio, don’t blame “today’s tools of tyranny”. Blame your own stupid self you say. If that isn't a statist, a veiled threat to my family if we don't go along with the sheep, then I don't know what is.
Now it's clear, your a damn hypocrite. Your profile spews 2A rights, but you can't figure out that the weapon of choice today is biological, not gun powder. You're stuck in the past - the wrong century.
Could this be another game changer?
Safe drug with a long history of human use for scabies and parasites.
Single dose could provide long term immunity.
https://www.nytimes.com/2019/06/26/health/scabies-treatment-ivermectin.html
Generic drug name Stromectol
“Deactivate” is commonly used.
Hydroxy helps zinc to enter the virus cell and kill it
Why hydroxy is used in combo with zinc ( zpack)
Maybe this is a good place to add this information...
No one here has mentioned it, but the herb wormwood is a powerful anti parasite treatment and is used in China for malaria.
“ Artemisinin is a natural product derived from the Chinese herb Artemisia annua (figure 1). During the Vietnam War, Ho Chi Minh asked Mao Zedong for help, because more North Vietnamese soldiers were dying from malaria than from armed conflicts. The Chinese government launched a program to find new antimalarial drugs. As a result, Tu Youyou, a Chinese scientist from the Chinese Academy of Traditional Chinese Medicine (Beijing, China), identified artemisinin as the active compound of A. annua in 1972 [1]. Its overwhelming antimalarial activity was demonstrated in numerous clinical studies by Chinese and Western scientists. Despite this success, the true potential of artemisinin was underestimated in the Western world for many years [2]. In the meantime, the World Health Organization officially recommends artemisinin and its derivatives, such as artesunate and artemether, for the treatment of malaria, particularly as a part of combination therapies with other antimalarial drugs.”
It is stocked in the veterinary world, used to deworm cattle and horses. In horses they claim it has been used so much many parasites are developing resistance to it. When it first came out it would wham parasites like magic. If it really is effective they better keep looking for another answer to work long term because it could cause the virus to become resistant after becoming the miracle cure.
I know animal drugs are not to be used on humans and no idea how long it would take for them to produce enough to be used on people for this virus.
Problem is, we dont know what dose it would take to create the concentration in human tissue needed to achieve the desired result. I read a paper where they used a 5 micromolar concentration in vitro. My crappy back of the envelope calculations led me to a resulting does of about 4000 micrograms per kilogram, but thats probably wrong.
Interesting stuff, humans can tolerate quite a lot of it, I read where doses of 2000 micrograms per kilogram have been used in humans.
Stupid article chloroquine phosphate is aquarium cleaner. Hydoxycloroquine sulphate is the medicine.
Ummmm....chloroquine phosphate is aquarium cleaner. Hydoxycloroquine sulphate is the medicine.
I lived in a third world country for a while and when I returned I was motivated to take Ivermectin. Though the horse paste is cheaper, I did not trust the blend. I took 1 cc per 100 lb. injectable. I did not inject, but took orally. Have taken it a few times since, with no bad side effects. Whole villages in Africa have been treated with Ivermectin. It is relatively safe and effective.
LOL
I am poor and tend to purchase meds from feed stores.
If these studies are reliable, the drugs must exert some activity/mechanism that also fights this disease.
Yes, these uses are off-label, which is the med profession's way of distancing themselves from endorsing such empirical practices. It seems to be a legal position, protecting them from any consequence from undocumented side effects, that sort of thing. Of course, when death is the alternative the profession is not going to stand in the way.
They are correct that - in time - we need clinical studies involving use of these drugs in unstudied circumstances. I hope time will clarify these unprecedented practices.
A few weeks back I was posting about the dog de-worming medicine, Fenbendazole being used for cancer treatment; I urged Rush Limbaugh to consider the off-label alternative. If traditional treatment does not help him, I hope he will think about the alternative.
Ivermectin is also used as a de-worming med.
It’s hard to get study funding for something that’s already out there and cheap.
I take fishcillin but my wife’s allergic to penicillin so she takes fishmycin
Undeniably a factor, but
***the drugs must exert some activity/mechanism that also fights this disease.***
as you pointed out, we seem to be fitting a square peg into a round hole. Further study might yield highly effective drugs exclusively against both parasites and viruses. As I understand, it is viruses where we are woefully short in effective treatments. At least I am curious as to how an anti-parasitic - a cellular form of biological life - can defeat a non-cellular molecular form of biology. Then too, penicillin came from bread mold.
Still, perhaps you are right.
Well, in human history, ‘Impossible’ has often just required Will and Faith. There aren’t many diseases that we haven’t found ways around, or at least ways through which we have lessened effects and prolonged life.
After all, it’s not as if we were trying to do what’s been proven impossible - and sometimes, approximations can be very helpful:
https://en.wikipedia.org/wiki/Squaring_the_circle
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