Posted on 01/20/2020 5:55:19 PM PST by nickcarraway
Sepsis kills more than twice as many people worldwide as once believed, and children in poor regions account for an excessive number of such deaths, researchers say.
Sepsis is an out-of-control immune response to infection that harms organs. People who survive sepsis can have lifelong disabilities.
In 2017, there were 48.9 million cases of sepsis and 11 million sepsis deaths worldwide -- that's one in five deaths that year.
"We are alarmed to find sepsis deaths are much higher than previously estimated, especially as the condition is both preventable and treatable," said senior author Dr. Mohsen Naghavi, a professor of health metrics sciences at the University of Washington School of Medicine in Seattle.
Low- and middle-income countries had 85 percent of the cases, with the most in sub-Saharan Africa, the South Pacific islands near Australia, and South, East and Southeast Asia, the study found.
Sepsis was more prevalent among females than males, and more than 40 percent of cases occurred in children under age 5, the researchers reported.
From 1990 to 2017, the number of cases fell from 60 million to about 49 million (down 19 percent), and sepsis deaths fell from nearly 16 million to 11 million (a 30 percent decrease).
Lower respiratory infection was the most common underlying cause of sepsis-related death in both 1990 and 2017, according to the report published Jan. 16 in The Lancet journal.
Naghavi called for renewed focus on sepsis prevention among newborns and on tackling antimicrobial resistance, a key driver of the condition.
Lead study author Dr. Kristina Rudd said the study highlights the need for basic public health strategies. She's an assistant professor of critical care medicine at the University of Pittsburgh.
"Vaccines, making sure everyone has access to a toilet and clean drinking water, adequate nutrition for children and maternal health care would address a lot of these cases," she said in a University of Pittsburgh news release.
Rudd pointed out that the issue hits close to home: Sepsis remains the leading killer of hospital patients in the United States.
"Everyone can reduce their odds of developing it by getting the flu shot, and the pneumonia vaccine when appropriate," she said. "Beyond that, we need to do a better job preventing hospital-acquired infections and chronic diseases, like diabetes, that make people more susceptible to infections."
If you ain’t bleeding or broke, you are infected. If you are infected, you are dying of sepsis. Most folks dying from pneumonia, die from Sepsis.
Turd world countries
Sepsis is very deceptive and under-recognized.
A deadly combination.
Sounds like wealth redistribution... vaccines, clean water.. women n children. After a few decades in healthcare i can rell ya.. anyone who thinks you are getting sepsis from not having clean drinking water is on the list to ignore.
Never let a crisis go to waste.
I believe a great many cases are contacted in hospitals. Which is one reason why earlier discharge with follow up care by a visiting nurse should be an option offered more often.
I almost lost my mom to this around Thanksgiving.
I DID lose my mom to exactly this 2 days before Thanksgiving 2008. My dad died of a heart attack 68 days later
So sorry. :(
It happens
Causes- or is the last step in a process?
H.A.T. Therapy for treatment of Sepsis. Differing views
https://clinicaltrials.gov/ct2/show/NCT03380507
“A recent small retrospective study , showed a significant decrease in mortality when patients with severe sepsis and septic shock are treated with a combination of Hydrocortisone, Vitamin C, and Thiamine.
HOWEVER, another article questions the effectiveness of the treatment.
“The results of the clinical trial by Fujii et al in this issue of JAMA,2 added to the cumulative evidence from 13 different studies performed in 10 different countries, indicate that high-dose vitamin C with or without thiamine and steroids does not provide significant survival benefits for patients with sepsis or septic shock.
Note: “high-dose vitamin C WITH OR WITHOUT thiamine and steroids”
This article looks a multiple studies. If they have this much variation from the protocol (Lets just give him vitamin C!) can you say they were really looking at the protocol?
Just putting this out there. People can review and make up there own minds.
More than guns? Has the NRA commented yet? You know like the assclowns at JAMA don’t hesitate to comment about firearm deaths.
Sepsis killed actress Patty Duke.
If doctors would approach this with an open mind, they will research Dr.Marik and sepsis. This guy is saving lives. If any of my family develops sepsis, I will insist on following Dr Mariks protocol or well be looking for another doctor.
If you want to catch something and get sick, stay in a hospital for a week. Go home with a nice case of drug resistant staph or meningitis.
Sepsis is an infection. most of the time you hear people talking about it because the infection is in the blood. if your infection is in an extremity, you will see a blue line traveling from the point of infection, slowly making its way up the hand/arm and eventually to the heart. You want to get treatment for it as soon as possible, getting to the heart can mean death.
“ Sepsis remains the leading killer of hospital patients in the United States.”
Yep, those Lines travel fast. Had 3 go from my thumb to my arm pit in a day. I got the infection in an open cut in my thumb while in the hospital. That sent me back for a week for multiple bacterial resistant iv antibiotics.
I just thought it was crazy how fast it happens.
You had something that hit very fast.
Mine took a week and only got to the end of my index finger.
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