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Study finds dopamine, biological clock link to snacking, overeating and obesity
phys.org ^ | 01/03/2020 | by University of Virginia

Posted on 01/04/2020 5:05:51 PM PST by BenLurkin

In a study published Thursday in the journal Current Biology, Güler and his colleagues demonstrate that the pleasure center of the brain that produces the chemical dopamine, and the brain's separate biological clock that regulates daily physiological rhythms, are linked, and that high-calorie foods—which bring pleasure—disrupt normal feeding schedules, resulting in overconsumption. Using mice as study models, the researchers mimicked the 24/7 availability of a high-fat diet, and showed that anytime snacking eventually results in obesity and related health problems.

Güler's team found that mice fed a diet comparable to a wild diet in calories and fats maintained normal eating and exercise schedules and proper weight. But mice fed high-calorie diets laden with fats and sugars began "snacking" at all hours and became obese.

Additionally, so-called "knockout" mice that had their dopamine signaling disrupted—meaning they didn't seek the rewarding pleasure of the high-fat diet—maintained a normal eating schedule and did not become obese, even when presented with the 24/7 availability of high-calorie feeds.

Güler said the human body, through thousands of years of evolution, is hard-wired to consume as much food as possible as long as it's available. He said this comes from a long earlier history when people hunted or gathered food and had brief periods of plenty, such as after a kill, and then potentially lengthy periods of famine. Humans also were potential prey to large animals and so actively sought food during the day, and sheltered and rested at night.

"We evolved under pressures we no longer have," Güler said. "It is natural for our bodies as organisms to want to consume as much as possible, to store fat, because the body doesn't know when the next meal is coming.

(Excerpt) Read more at phys.org ...


TOPICS: Food; Health/Medicine
KEYWORDS: biologicalclock; dopamine; overeating; snacking
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To: EEGator

>>> Just vomit after you eat too much.
>>> Do some cocaine, and take up smoking.

Shhhh! Don’t give away the secret.


21 posted on 01/04/2020 5:43:51 PM PST by Jeff Chandler (BLACK LIVES MAGA)
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To: Jeff Chandler

My bad.


22 posted on 01/04/2020 5:46:09 PM PST by EEGator
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To: cherry

I’ve worked my way up to 5 day fasts. Lost over a hundred pounds, relieved my body of many aches and pains related to joint stress and arthritis.

The best part of fasting is that it’s free and requires no expensive foods or supplements nor labor intensive meal prep or menu planning.


23 posted on 01/04/2020 5:47:03 PM PST by Valpal1
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To: House Atreides
I've been doing 4/20 for a 18 months. Every few weeks I toss in a 0/24.

I was in shape, I'm in better shape. I was strong, I'm stronger. I had clarity of thought, my mind is sharper. I was good looking, hubba hubba.

Don't neglect balance training. For real.

As far as strength and health generally... unless you are gonna do it faithfully forever it's a waste, don't bother.

24 posted on 01/04/2020 5:51:40 PM PST by coaster123 (XLV-MMXX)
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To: EEGator

I’ve solved the lack of sleep issue - I almost always get enough sleep.

Working on the stress thing - getting better.

:)

Don’t seem to be losing weight (yet) however...


25 posted on 01/04/2020 5:53:20 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ and our Free Constitutional Republic!)
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To: Jeff Chandler

Putting down success because you’re deficient. What kind of thinking is that other than from a leftist mindset?


26 posted on 01/04/2020 5:55:33 PM PST by coaster123 (XLV-MMXX)
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To: EEGator
Just vomit after you eat too much. Do some cocaine, and take up smoking.


27 posted on 01/04/2020 6:02:21 PM PST by DoodleBob (Gravity's waiting period is about 9.8 m/s^2)
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To: Jim W N

Are you exercising?


28 posted on 01/04/2020 6:06:42 PM PST by EEGator
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To: DoodleBob

See...lean.


29 posted on 01/04/2020 6:07:05 PM PST by EEGator
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To: EEGator
Yeap...then he played with a buncha pot and munchies guys....


30 posted on 01/04/2020 6:11:56 PM PST by DoodleBob (Gravity's waiting period is about 9.8 m/s^2)
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To: House Atreides

Could you explain what an 8/16 intermittent fasting regime actually is?


31 posted on 01/04/2020 6:12:17 PM PST by ladyjane
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To: DoodleBob

He should have stuck to cocaine...


32 posted on 01/04/2020 6:15:06 PM PST by EEGator
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To: EEGator

Exercising is a really punishing way to lose weight IMO, unless you like exercising which I don’t (and I’m an athlete too...). The key - just eat less.

I used to exercise to lose weight and afterwards, I’d feel like I had earned the right to eat more. Self-defeating.

I watched Ford v. Ferrari (good movie) where Christian Bale looked almost emaciated. Turns out he had to lose a bunch of weight for the part. When asked how he lost the weigh, he said that he just ate less.

At some point that’s will probably what I will do.


33 posted on 01/04/2020 6:16:39 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ and our Free Constitutional Republic!)
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To: BenLurkin
Güler and his colleagues demonstrate that the pleasure center of the brain that produces the chemical dopamine, and the brain's separate biological clock that regulates daily physiological rhythms, are linked, and that high-calorie foods—which bring pleasure—disrupt normal feeding schedules, resulting in overconsumption.

So activating the pleasure center of your brain makes you over eat?

Hmmm

34 posted on 01/04/2020 6:18:10 PM PST by Harmless Teddy Bear (A hero is a hero no matter what medal they give him. Likewise a schmuck is still a schmuck.)
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To: Jim W N

Look up Christian Bale in The Machinist.

I agree that diet is the most important component by far in weight loss.


35 posted on 01/04/2020 6:18:31 PM PST by EEGator
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To: Valpal1

I admire your discipline and achievement.


36 posted on 01/04/2020 6:18:50 PM PST by wally_bert (Your methods were a little incomplete, you too for that matter.)
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To: EEGator

...and stayed away from Chris Robinson.


37 posted on 01/04/2020 6:22:19 PM PST by DoodleBob (Gravity's waiting period is about 9.8 m/s^2)
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To: DoodleBob

That’s good advice for his 3 ex-wives as well.


38 posted on 01/04/2020 6:26:10 PM PST by EEGator
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To: coaster123
What kind of thinking is that other than from a leftist mindset?

You got me.

39 posted on 01/04/2020 6:32:09 PM PST by Jeff Chandler (BLACK LIVES MAGA)
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To: EEGator

That is crazy - going too far IMO.

Check this out - Bale in American Hustle.

Can't believe all this ballooning up and down is good for you.

40 posted on 01/04/2020 6:33:26 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ and our Free Constitutional Republic!)
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